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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCB8
Full Name:
ATP-binding cassette sub-family B member 8, mitochondrial
Alias:
Mitochondrial ATP-binding cassette 1
Type:
Mass (Da):
Number AA:
UniProt ID:
Q9NUT2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043190
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042626
PhosphoSite+
KinaseNET
Biological Process:
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
L
P
P
L
R
F
Q
T
F
S
A
V
R
N
T
Site 2
S29
P
L
R
F
Q
T
F
S
A
V
R
N
T
W
R
Site 3
T34
T
F
S
A
V
R
N
T
W
R
N
G
K
T
G
Site 4
S51
H
K
A
E
G
E
Y
S
D
G
Y
R
S
S
S
Site 5
Y54
E
G
E
Y
S
D
G
Y
R
S
S
S
L
L
R
Site 6
S56
E
Y
S
D
G
Y
R
S
S
S
L
L
R
A
V
Site 7
S57
Y
S
D
G
Y
R
S
S
S
L
L
R
A
V
A
Site 8
S58
S
D
G
Y
R
S
S
S
L
L
R
A
V
A
H
Site 9
S68
R
A
V
A
H
L
R
S
Q
L
W
A
H
L
P
Site 10
S84
A
P
L
A
P
R
W
S
P
S
A
W
C
W
V
Site 11
S86
L
A
P
R
W
S
P
S
A
W
C
W
V
G
G
Site 12
S102
L
L
G
P
M
V
L
S
K
H
P
H
L
C
L
Site 13
S122
A
E
E
A
P
P
A
S
S
T
P
H
V
V
G
Site 14
S123
E
E
A
P
P
A
S
S
T
P
H
V
V
G
S
Site 15
T124
E
A
P
P
A
S
S
T
P
H
V
V
G
S
R
Site 16
Y179
L
V
E
V
V
A
K
Y
T
R
D
H
V
G
S
Site 17
S186
Y
T
R
D
H
V
G
S
F
M
T
E
S
Q
N
Site 18
S191
V
G
S
F
M
T
E
S
Q
N
L
S
T
H
L
Site 19
S233
D
M
R
R
A
L
F
S
S
L
L
R
Q
D
I
Site 20
S234
M
R
R
A
L
F
S
S
L
L
R
Q
D
I
T
Site 21
T241
S
L
L
R
Q
D
I
T
F
F
D
A
N
K
T
Site 22
T256
G
Q
L
V
S
R
L
T
T
D
V
Q
E
F
K
Site 23
T257
Q
L
V
S
R
L
T
T
D
V
Q
E
F
K
S
Site 24
S264
T
D
V
Q
E
F
K
S
S
F
K
L
V
I
S
Site 25
S265
D
V
Q
E
F
K
S
S
F
K
L
V
I
S
Q
Site 26
S276
V
I
S
Q
G
L
R
S
C
T
Q
V
A
G
C
Site 27
S288
A
G
C
L
V
S
L
S
M
L
S
T
R
L
T
Site 28
S291
L
V
S
L
S
M
L
S
T
R
L
T
L
L
L
Site 29
T295
S
M
L
S
T
R
L
T
L
L
L
M
V
A
T
Site 30
T310
P
A
L
M
G
V
G
T
L
M
G
S
G
L
R
Site 31
S314
G
V
G
T
L
M
G
S
G
L
R
K
L
S
R
Site 32
S320
G
S
G
L
R
K
L
S
R
Q
C
Q
E
Q
I
Site 33
Y357
E
Q
R
E
E
E
R
Y
G
A
E
L
E
A
C
Site 34
S382
I
A
L
F
Q
G
L
S
N
I
A
F
N
C
M
Site 35
T420
S
F
L
V
A
S
Q
T
V
Q
R
S
M
A
N
Site 36
S429
Q
R
S
M
A
N
L
S
V
L
F
G
Q
V
V
Site 37
S471
P
K
E
Q
L
R
G
S
V
T
F
Q
N
V
C
Site 38
T473
E
Q
L
R
G
S
V
T
F
Q
N
V
C
F
S
Site 39
T514
G
Q
S
G
G
G
K
T
T
V
A
S
L
L
E
Site 40
T515
Q
S
G
G
G
K
T
T
V
A
S
L
L
E
R
Site 41
S518
G
G
K
T
T
V
A
S
L
L
E
R
F
Y
D
Site 42
Y524
A
S
L
L
E
R
F
Y
D
P
T
A
G
V
V
Site 43
T540
L
D
G
R
D
L
R
T
L
D
P
S
W
L
R
Site 44
S544
D
L
R
T
L
D
P
S
W
L
R
G
Q
V
V
Site 45
S577
R
F
G
K
L
E
A
S
D
E
E
V
Y
T
A
Site 46
T583
A
S
D
E
E
V
Y
T
A
A
R
E
A
N
A
Site 47
T595
A
N
A
H
E
F
I
T
S
F
P
E
G
Y
N
Site 48
S596
N
A
H
E
F
I
T
S
F
P
E
G
Y
N
T
Site 49
Y601
I
T
S
F
P
E
G
Y
N
T
V
V
G
E
R
Site 50
T603
S
F
P
E
G
Y
N
T
V
V
G
E
R
G
T
Site 51
T610
T
V
V
G
E
R
G
T
T
L
S
G
G
Q
K
Site 52
T611
V
V
G
E
R
G
T
T
L
S
G
G
Q
K
Q
Site 53
S613
G
E
R
G
T
T
L
S
G
G
Q
K
Q
R
L
Site 54
S646
T
S
A
L
D
A
E
S
E
R
V
V
Q
E
A
Site 55
S658
Q
E
A
L
D
R
A
S
A
G
R
T
V
L
V
Site 56
T662
D
R
A
S
A
G
R
T
V
L
V
I
A
H
R
Site 57
T717
Q
A
L
D
A
P
R
T
A
A
P
P
P
K
K
Site 58
S730
K
K
P
E
G
P
R
S
H
Q
H
K
S
_
_
Site 59
S735
P
R
S
H
Q
H
K
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation