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Updated November 2019
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Protein Info
Short Name:
FAM105A
Full Name:
Protein FAM105A
Alias:
Type:
Mass (Da):
42196
Number AA:
356
UniProt ID:
Q9NUU6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
A
A
T
R
S
P
T
R
A
R
Site 2
S6
_
_
M
A
A
T
R
S
P
T
R
A
R
E
R
Site 3
T8
M
A
A
T
R
S
P
T
R
A
R
E
R
E
R
Site 4
S16
R
A
R
E
R
E
R
S
G
A
P
A
A
G
S
Site 5
S23
S
G
A
P
A
A
G
S
D
Q
V
H
S
W
M
Site 6
T39
A
T
S
Q
A
L
D
T
V
W
R
M
A
K
G
Site 7
Y68
Y
F
R
R
L
H
L
Y
S
G
H
K
L
K
W
Site 8
Y79
K
L
K
W
W
I
G
Y
L
Q
R
K
F
K
R
Site 9
S89
R
K
F
K
R
N
L
S
V
E
A
E
V
D
L
Site 10
S98
E
A
E
V
D
L
L
S
Y
C
A
R
E
W
K
Site 11
Y99
A
E
V
D
L
L
S
Y
C
A
R
E
W
K
G
Site 12
T108
A
R
E
W
K
G
E
T
P
R
N
K
L
M
R
Site 13
Y118
N
K
L
M
R
K
A
Y
E
E
L
F
W
R
H
Site 14
Y138
R
Q
V
R
R
D
N
Y
D
A
L
R
S
V
L
Site 15
S154
Q
I
F
S
Q
G
I
S
F
P
S
W
M
K
E
Site 16
S193
G
P
E
K
Y
T
G
S
N
V
F
G
K
L
R
Site 17
Y202
V
F
G
K
L
R
K
Y
V
E
L
L
K
T
Q
Site 18
T208
K
Y
V
E
L
L
K
T
Q
W
T
E
F
N
G
Site 19
Y219
E
F
N
G
I
R
D
Y
H
K
R
G
S
M
C
Site 20
S224
R
D
Y
H
K
R
G
S
M
C
N
T
L
F
S
Site 21
T228
K
R
G
S
M
C
N
T
L
F
S
D
A
I
L
Site 22
Y237
F
S
D
A
I
L
E
Y
K
L
Y
E
A
L
K
Site 23
Y249
A
L
K
F
I
M
L
Y
Q
V
T
E
V
Y
E
Site 24
Y255
L
Y
Q
V
T
E
V
Y
E
Q
M
K
T
K
K
Site 25
T260
E
V
Y
E
Q
M
K
T
K
K
V
I
P
S
L
Site 26
S273
S
L
F
R
L
L
F
S
R
E
T
S
S
D
P
Site 27
T276
R
L
L
F
S
R
E
T
S
S
D
P
L
S
F
Site 28
S277
L
L
F
S
R
E
T
S
S
D
P
L
S
F
M
Site 29
S278
L
F
S
R
E
T
S
S
D
P
L
S
F
M
M
Site 30
S282
E
T
S
S
D
P
L
S
F
M
M
N
H
L
N
Site 31
T294
H
L
N
S
V
G
D
T
C
G
L
E
Q
I
D
Site 32
Y330
S
R
D
F
E
V
C
Y
P
E
E
P
L
R
D
Site 33
Y351
L
T
E
N
D
R
H
Y
H
I
P
V
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation