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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NDFIP2
Full Name:
NEDD4 family-interacting protein 2
Alias:
KIAA1165; MAPK-activating protein PM04/PM05/PM06/PM07; N4wbp5a; Nedd4 family interacting protein 2; NEDD4 WW domain-binding protein 5A; NFIP2; NF-kappa-B-activating protein 413
Type:
Adaptor/scaffold
Mass (Da):
36390
Number AA:
336
UniProt ID:
Q9NV92
International Prot ID:
IPI00385038
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
GO:0005768
Uniprot
OncoNet
Molecular Function:
GO:0050699
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0010629
GO:0051224
GO:0032410
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
R
R
R
S
Q
R
V
C
A
S
G
Site 2
S12
R
S
Q
R
V
C
A
S
G
P
S
M
L
N
S
Site 3
S19
S
G
P
S
M
L
N
S
A
R
G
A
P
E
L
Site 4
T30
A
P
E
L
L
R
G
T
A
T
N
A
E
V
S
Site 5
S46
A
A
A
G
A
T
G
S
E
E
L
P
P
G
D
Site 6
T67
G
G
R
G
P
A
A
T
T
S
S
T
G
V
A
Site 7
S83
G
A
E
H
G
E
D
S
L
S
R
K
P
D
P
Site 8
S85
E
H
G
E
D
S
L
S
R
K
P
D
P
E
P
Site 9
T102
M
D
H
H
Q
P
G
T
G
R
Y
Q
V
L
L
Site 10
S115
L
L
N
E
E
D
N
S
E
S
S
A
I
E
Q
Site 11
T125
S
A
I
E
Q
P
P
T
S
N
P
A
P
Q
I
Site 12
S126
A
I
E
Q
P
P
T
S
N
P
A
P
Q
I
V
Site 13
T144
S
S
A
P
A
L
E
T
D
S
S
P
P
P
Y
Site 14
S146
A
P
A
L
E
T
D
S
S
P
P
P
Y
S
S
Site 15
S147
P
A
L
E
T
D
S
S
P
P
P
Y
S
S
I
Site 16
Y151
T
D
S
S
P
P
P
Y
S
S
I
T
V
E
V
Site 17
S152
D
S
S
P
P
P
Y
S
S
I
T
V
E
V
P
Site 18
S153
S
S
P
P
P
Y
S
S
I
T
V
E
V
P
T
Site 19
T155
P
P
P
Y
S
S
I
T
V
E
V
P
T
T
S
Site 20
T161
I
T
V
E
V
P
T
T
S
D
T
E
V
Y
G
Site 21
T164
E
V
P
T
T
S
D
T
E
V
Y
G
E
F
Y
Site 22
Y171
T
E
V
Y
G
E
F
Y
P
V
P
P
P
Y
S
Site 23
S178
Y
P
V
P
P
P
Y
S
V
A
T
S
L
P
T
Site 24
S182
P
P
Y
S
V
A
T
S
L
P
T
Y
D
E
A
Site 25
Y186
V
A
T
S
L
P
T
Y
D
E
A
E
K
A
K
Site 26
S205
A
A
A
A
A
E
T
S
Q
R
I
Q
E
E
E
Site 27
S220
C
P
P
R
D
D
F
S
D
A
D
Q
L
R
V
Site 28
Y314
F
F
R
G
F
V
N
Y
L
K
V
R
N
M
S
Site 29
S321
Y
L
K
V
R
N
M
S
E
S
M
A
A
A
H
Site 30
S323
K
V
R
N
M
S
E
S
M
A
A
A
H
R
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation