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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARVA
Full Name:
Alpha-parvin
Alias:
Actopaxin; Alpha-parvin: Calponin-like integrin-linked kinase-binding protein: CH-ILKBP: Matrix-remodeling-associated protein 2: Actopaxin: Alpha-parvin: Calponin-like integrin-linked kinase-binding protein: CH-ILKBP: Matrix-remodeling-associated protein 2: Actopaxin; Calponin-like integrin-linked kinase binding protein; CH-ILKBP; FLJ10793; FLJ12254; Matrix-remodelling associated 2; MXRA2; Parvin, alpha
Type:
Adaptor/scaffold
Mass (Da):
42244
Number AA:
372
UniProt ID:
Q9NVD7
International Prot ID:
IPI00018963
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005925
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0009987
GO:0022610
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
A
T
S
P
Q
K
S
P
S
Site 2
S4
_
_
_
_
M
A
T
S
P
Q
K
S
P
S
V
Site 3
S8
M
A
T
S
P
Q
K
S
P
S
V
P
K
S
P
Site 4
S10
T
S
P
Q
K
S
P
S
V
P
K
S
P
T
P
Site 5
S14
K
S
P
S
V
P
K
S
P
T
P
K
S
P
P
Site 6
T16
P
S
V
P
K
S
P
T
P
K
S
P
P
S
R
Site 7
S19
P
K
S
P
T
P
K
S
P
P
S
R
K
K
D
Site 8
S22
P
T
P
K
S
P
P
S
R
K
K
D
D
S
F
Site 9
S28
P
S
R
K
K
D
D
S
F
L
G
K
L
G
G
Site 10
T36
F
L
G
K
L
G
G
T
L
A
R
R
K
K
A
Site 11
S47
R
K
K
A
K
E
V
S
E
L
Q
E
E
G
M
Site 12
S62
N
A
I
N
L
P
L
S
P
I
P
F
E
L
D
Site 13
S88
R
T
M
V
D
P
N
S
R
S
D
P
K
L
Q
Site 14
S90
M
V
D
P
N
S
R
S
D
P
K
L
Q
E
L
Site 15
Y124
K
D
L
A
E
D
L
Y
D
G
Q
V
L
Q
K
Site 16
S138
K
L
F
E
K
L
E
S
E
K
L
N
V
A
E
Site 17
S149
N
V
A
E
V
T
Q
S
E
I
A
Q
K
Q
K
Site 18
T167
V
L
E
K
I
N
E
T
L
K
L
P
P
R
S
Site 19
S174
T
L
K
L
P
P
R
S
I
K
W
N
V
D
S
Site 20
S181
S
I
K
W
N
V
D
S
V
H
A
K
S
L
V
Site 21
S242
T
G
N
T
E
A
L
S
G
R
H
E
R
D
A
Site 22
T252
H
E
R
D
A
F
D
T
L
F
D
H
A
P
D
Site 23
T316
P
L
H
S
F
F
L
T
P
D
S
F
E
Q
K
Site 24
S319
S
F
F
L
T
P
D
S
F
E
Q
K
V
L
N
Site 25
Y362
K
S
T
L
R
V
L
Y
N
L
F
T
K
Y
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation