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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PANK4
Full Name:
Pantothenate kinase 4
Alias:
EC 2.7.1.33; Pantothenic acid kinase; Pantothenic acid kinase 4
Type:
Cofactors and Vitamins - pantothenate and CoA biosynthesis, Kinase (non-protein)
Mass (Da):
85991
Number AA:
773
UniProt ID:
Q9NVE7
International Prot ID:
IPI00939845
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004594
PhosphoSite+
KinaseNET
Biological Process:
GO:0015937
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
E
C
G
A
S
G
S
G
S
S
G
D
Site 2
S9
A
E
C
G
A
S
G
S
G
S
S
G
D
S
L
Site 3
S11
C
G
A
S
G
S
G
S
S
G
D
S
L
D
K
Site 4
S15
G
S
G
S
S
G
D
S
L
D
K
S
I
T
L
Site 5
S19
S
G
D
S
L
D
K
S
I
T
L
P
P
D
E
Site 6
T21
D
S
L
D
K
S
I
T
L
P
P
D
E
I
F
Site 7
Y50
G
S
L
T
K
L
A
Y
Y
S
T
V
Q
H
K
Site 8
Y51
S
L
T
K
L
A
Y
Y
S
T
V
Q
H
K
V
Site 9
T53
T
K
L
A
Y
Y
S
T
V
Q
H
K
V
A
K
Site 10
S63
H
K
V
A
K
V
R
S
F
D
H
S
G
K
D
Site 11
S67
K
V
R
S
F
D
H
S
G
K
D
T
E
R
E
Site 12
T71
F
D
H
S
G
K
D
T
E
R
E
H
E
P
P
Site 13
Y79
E
R
E
H
E
P
P
Y
E
I
S
V
Q
E
E
Site 14
S82
H
E
P
P
Y
E
I
S
V
Q
E
E
I
T
A
Site 15
T123
E
T
K
V
I
Q
A
T
G
G
G
A
Y
K
F
Site 16
Y169
I
P
H
E
A
F
V
Y
Q
K
D
S
D
P
E
Site 17
S173
A
F
V
Y
Q
K
D
S
D
P
E
F
R
F
Q
Site 18
S215
R
F
E
W
V
G
G
S
S
I
G
G
G
T
F
Site 19
T230
W
G
L
G
A
L
L
T
K
T
K
K
F
D
E
Site 20
S243
D
E
L
L
H
L
A
S
R
G
Q
H
S
N
V
Site 21
Y258
D
M
L
V
R
D
V
Y
G
G
A
H
Q
T
L
Site 22
S279
I
A
S
S
F
G
K
S
A
T
A
D
Q
E
F
Site 23
S294
S
K
E
D
M
A
K
S
L
L
H
M
I
S
N
Site 24
S315
C
L
H
A
R
L
H
S
L
D
R
V
Y
F
G
Site 25
T332
F
I
R
G
H
P
V
T
M
R
T
I
T
Y
S
Site 26
T335
G
H
P
V
T
M
R
T
I
T
Y
S
I
N
F
Site 27
Y383
Q
Y
S
W
G
E
N
Y
A
G
S
S
G
L
M
Site 28
S386
W
G
E
N
Y
A
G
S
S
G
L
M
S
A
S
Site 29
S387
G
E
N
Y
A
G
S
S
G
L
M
S
A
S
P
Site 30
S391
A
G
S
S
G
L
M
S
A
S
P
E
L
G
P
Site 31
S393
S
S
G
L
M
S
A
S
P
E
L
G
P
A
Q
Site 32
S404
G
P
A
Q
R
A
R
S
G
T
F
D
L
L
E
Site 33
T406
A
Q
R
A
R
S
G
T
F
D
L
L
E
M
D
Site 34
S430
P
L
L
L
D
P
P
S
Y
V
P
D
T
V
D
Site 35
T435
P
P
S
Y
V
P
D
T
V
D
L
T
D
D
A
Site 36
T439
V
P
D
T
V
D
L
T
D
D
A
L
A
R
K
Site 37
Y447
D
D
A
L
A
R
K
Y
W
L
T
C
F
E
E
Site 38
T450
L
A
R
K
Y
W
L
T
C
F
E
E
A
L
D
Site 39
S466
V
V
K
R
A
V
A
S
Q
P
D
S
V
D
A
Site 40
S470
A
V
A
S
Q
P
D
S
V
D
A
A
E
R
A
Site 41
Y484
A
E
K
F
R
Q
K
Y
W
N
K
L
Q
T
L
Site 42
T490
K
Y
W
N
K
L
Q
T
L
R
Q
Q
P
F
A
Site 43
S505
Y
G
T
L
T
V
R
S
L
L
D
T
R
E
H
Site 44
T509
T
V
R
S
L
L
D
T
R
E
H
C
L
N
E
Site 45
Y523
E
F
N
F
P
D
P
Y
S
K
V
K
Q
R
E
Site 46
S524
F
N
F
P
D
P
Y
S
K
V
K
Q
R
E
N
Site 47
Y583
A
V
L
E
S
D
P
Y
F
G
F
E
E
A
K
Site 48
S602
E
R
P
W
L
V
D
S
Y
S
E
W
L
Q
R
Site 49
Y603
R
P
W
L
V
D
S
Y
S
E
W
L
Q
R
L
Site 50
S604
P
W
L
V
D
S
Y
S
E
W
L
Q
R
L
K
Site 51
S697
L
V
Q
T
G
S
S
S
P
C
L
D
L
S
R
Site 52
S703
S
S
P
C
L
D
L
S
R
L
D
K
G
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation