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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INTS7
Full Name:
Integrator complex subunit 7
Alias:
C1orf73; Chromosome 1 open reading frame 73; DKFZP434B168; INT7
Type:
Unknown function
Mass (Da):
106834
Number AA:
962
UniProt ID:
Q9NVH2
International Prot ID:
IPI00743871
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0032039
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
S
N
S
T
K
S
F
L
A
D
A
G
Y
Site 2
Y15
S
F
L
A
D
A
G
Y
G
E
Q
E
L
D
A
Site 3
S35
E
L
D
K
G
L
R
S
G
K
L
G
E
Q
C
Site 4
S109
E
F
V
K
R
I
F
S
V
I
H
S
N
D
P
Site 5
S113
R
I
F
S
V
I
H
S
N
D
P
V
A
R
A
Site 6
S131
R
M
L
G
S
L
A
S
I
I
P
E
R
K
N
Site 7
S142
E
R
K
N
A
H
H
S
I
R
Q
S
L
D
S
Site 8
S146
A
H
H
S
I
R
Q
S
L
D
S
H
D
N
V
Site 9
S149
S
I
R
Q
S
L
D
S
H
D
N
V
E
V
E
Site 10
S181
V
G
I
C
N
K
I
S
E
M
I
Q
G
L
A
Site 11
S212
H
H
D
A
I
L
A
S
S
A
R
Q
L
L
Q
Site 12
S213
H
D
A
I
L
A
S
S
A
R
Q
L
L
Q
Q
Site 13
T223
Q
L
L
Q
Q
L
V
T
S
Y
P
S
T
K
M
Site 14
Y225
L
Q
Q
L
V
T
S
Y
P
S
T
K
M
V
I
Site 15
Y259
Q
I
Q
L
L
L
Q
Y
L
K
N
D
P
R
K
Site 16
T283
L
K
L
L
A
N
K
T
P
H
T
W
S
R
E
Site 17
T286
L
A
N
K
T
P
H
T
W
S
R
E
N
I
Q
Site 18
Y304
E
C
A
L
Q
T
P
Y
D
S
L
K
L
G
M
Site 19
S313
S
L
K
L
G
M
L
S
V
L
S
T
L
S
G
Site 20
S336
S
I
V
P
G
N
V
S
S
S
P
R
S
S
D
Site 21
S337
I
V
P
G
N
V
S
S
S
P
R
S
S
D
L
Site 22
S338
V
P
G
N
V
S
S
S
P
R
S
S
D
L
V
Site 23
S341
N
V
S
S
S
P
R
S
S
D
L
V
K
L
A
Site 24
S342
V
S
S
S
P
R
S
S
D
L
V
K
L
A
Q
Site 25
Y353
K
L
A
Q
E
C
C
Y
H
N
N
R
G
I
A
Site 26
T371
V
R
V
L
T
N
I
T
V
S
C
Q
E
K
D
Site 27
S398
E
S
L
L
V
L
C
S
Q
D
D
S
P
G
A
Site 28
S402
V
L
C
S
Q
D
D
S
P
G
A
Q
A
T
L
Site 29
S427
A
K
G
R
P
H
L
S
Q
S
V
V
E
T
L
Site 30
S429
G
R
P
H
L
S
Q
S
V
V
E
T
L
L
T
Site 31
T436
S
V
V
E
T
L
L
T
Q
L
H
S
A
Q
D
Site 32
S440
T
L
L
T
Q
L
H
S
A
Q
D
A
A
R
I
Site 33
T483
K
V
I
G
R
S
A
T
D
K
Q
Q
E
L
L
Site 34
S519
V
I
K
Q
Q
L
E
S
V
S
N
G
W
T
V
Site 35
T525
E
S
V
S
N
G
W
T
V
Y
R
I
A
R
Q
Site 36
Y527
V
S
N
G
W
T
V
Y
R
I
A
R
Q
A
S
Site 37
S534
Y
R
I
A
R
Q
A
S
R
M
G
N
H
D
M
Site 38
Y546
H
D
M
A
K
E
L
Y
Q
S
L
L
T
Q
V
Site 39
T551
E
L
Y
Q
S
L
L
T
Q
V
A
S
E
H
F
Site 40
Y559
Q
V
A
S
E
H
F
Y
F
W
L
N
S
L
K
Site 41
T576
S
H
A
E
Q
C
L
T
G
L
Q
E
E
N
Y
Site 42
Y583
T
G
L
Q
E
E
N
Y
S
S
A
L
S
C
I
Site 43
S584
G
L
Q
E
E
N
Y
S
S
A
L
S
C
I
A
Site 44
S588
E
N
Y
S
S
A
L
S
C
I
A
E
S
L
K
Site 45
T605
H
K
G
I
A
S
L
T
A
A
S
T
P
L
N
Site 46
S615
S
T
P
L
N
P
L
S
F
Q
C
E
F
V
K
Site 47
S640
Q
L
I
C
T
C
N
S
L
K
T
S
P
P
P
Site 48
S644
T
C
N
S
L
K
T
S
P
P
P
A
I
A
T
Site 49
S674
I
S
N
Q
M
K
Q
S
M
E
E
F
R
S
L
Site 50
S680
Q
S
M
E
E
F
R
S
L
A
S
R
Y
G
D
Site 51
Y689
A
S
R
Y
G
D
L
Y
Q
A
S
F
D
A
D
Site 52
S692
Y
G
D
L
Y
Q
A
S
F
D
A
D
S
A
T
Site 53
S697
Q
A
S
F
D
A
D
S
A
T
L
R
N
V
E
Site 54
T699
S
F
D
A
D
S
A
T
L
R
N
V
E
L
Q
Site 55
S726
A
L
I
L
D
P
E
S
A
S
F
Q
E
Y
G
Site 56
S728
I
L
D
P
E
S
A
S
F
Q
E
Y
G
S
T
Site 57
Y732
E
S
A
S
F
Q
E
Y
G
S
T
G
T
A
H
Site 58
T735
S
F
Q
E
Y
G
S
T
G
T
A
H
A
D
S
Site 59
S742
T
G
T
A
H
A
D
S
E
Y
E
R
R
M
M
Site 60
Y744
T
A
H
A
D
S
E
Y
E
R
R
M
M
S
V
Site 61
Y752
E
R
R
M
M
S
V
Y
N
H
V
L
E
E
V
Site 62
S761
H
V
L
E
E
V
E
S
L
N
R
K
Y
T
P
Site 63
Y766
V
E
S
L
N
R
K
Y
T
P
V
S
Y
M
H
Site 64
T767
E
S
L
N
R
K
Y
T
P
V
S
Y
M
H
T
Site 65
Y794
V
P
L
S
F
Q
R
Y
F
F
Q
K
L
Q
S
Site 66
S803
F
Q
K
L
Q
S
T
S
I
K
L
A
L
S
P
Site 67
S809
T
S
I
K
L
A
L
S
P
S
P
R
N
P
A
Site 68
S811
I
K
L
A
L
S
P
S
P
R
N
P
A
E
P
Site 69
S839
E
G
V
V
Q
H
G
S
K
P
G
L
F
R
K
Site 70
S855
Q
S
V
C
L
N
V
S
S
T
L
Q
S
K
S
Site 71
S856
S
V
C
L
N
V
S
S
T
L
Q
S
K
S
G
Site 72
T857
V
C
L
N
V
S
S
T
L
Q
S
K
S
G
Q
Site 73
S860
N
V
S
S
T
L
Q
S
K
S
G
Q
D
Y
K
Site 74
S862
S
S
T
L
Q
S
K
S
G
Q
D
Y
K
I
P
Site 75
Y866
Q
S
K
S
G
Q
D
Y
K
I
P
I
D
N
M
Site 76
T874
K
I
P
I
D
N
M
T
N
E
M
E
Q
R
V
Site 77
Y887
R
V
E
P
H
N
D
Y
F
S
T
Q
F
L
L
Site 78
T905
I
L
G
T
H
N
I
T
V
E
S
S
V
K
D
Site 79
T920
A
N
G
I
V
W
K
T
G
P
R
T
T
I
F
Site 80
T925
W
K
T
G
P
R
T
T
I
F
V
K
S
L
E
Site 81
S930
R
T
T
I
F
V
K
S
L
E
D
P
Y
S
Q
Site 82
Y935
V
K
S
L
E
D
P
Y
S
Q
Q
I
R
L
Q
Site 83
S936
K
S
L
E
D
P
Y
S
Q
Q
I
R
L
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation