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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRMT7
Full Name:
Protein arginine N-methyltransferase 7
Alias:
Histone-arginine N-methyltransferase PRMT7;[Myelin basic protein]-arginine N-methyltransferase PRMT7
Type:
Mass (Da):
78459
Number AA:
692
UniProt ID:
Q9NVM4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
C
S
R
A
N
P
T
T
G
S
V
E
W
L
E
Site 2
S14
R
A
N
P
T
T
G
S
V
E
W
L
E
E
D
Site 3
Y24
W
L
E
E
D
E
H
Y
D
Y
H
Q
E
I
A
Site 4
Y26
E
E
D
E
H
Y
D
Y
H
Q
E
I
A
R
S
Site 5
S34
H
Q
E
I
A
R
S
S
Y
A
D
M
L
H
D
Site 6
Y35
Q
E
I
A
R
S
S
Y
A
D
M
L
H
D
K
Site 7
Y48
D
K
D
R
N
V
K
Y
Y
Q
G
I
R
A
A
Site 8
Y49
K
D
R
N
V
K
Y
Y
Q
G
I
R
A
A
V
Site 9
S57
Q
G
I
R
A
A
V
S
R
V
K
D
R
G
Q
Site 10
T127
N
K
H
S
T
E
V
T
V
G
P
E
G
D
M
Site 11
S158
I
G
E
G
A
L
P
S
Y
E
H
A
H
R
H
Site 12
Y159
G
E
G
A
L
P
S
Y
E
H
A
H
R
H
L
Site 13
T179
E
A
V
P
H
R
A
T
V
Y
A
Q
L
V
E
Site 14
S224
E
S
C
P
G
A
P
S
V
C
D
I
Q
L
N
Site 15
S253
P
M
F
S
I
D
F
S
K
Q
V
S
S
S
A
Site 16
S257
I
D
F
S
K
Q
V
S
S
S
A
A
C
H
S
Site 17
S258
D
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
Site 18
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
R
Site 19
S264
S
S
S
A
A
C
H
S
R
R
F
E
P
L
T
Site 20
T271
S
R
R
F
E
P
L
T
S
G
R
A
Q
V
V
Site 21
S272
R
R
F
E
P
L
T
S
G
R
A
Q
V
V
L
Site 22
Y342
L
V
A
H
H
D
D
Y
C
V
W
Y
S
L
Q
Site 23
T351
V
W
Y
S
L
Q
R
T
S
P
E
K
N
E
R
Site 24
S352
W
Y
S
L
Q
R
T
S
P
E
K
N
E
R
V
Site 25
T388
E
I
N
D
Q
D
R
T
D
R
Y
V
Q
A
L
Site 26
Y391
D
Q
D
R
T
D
R
Y
V
Q
A
L
R
T
V
Site 27
S431
E
Q
V
F
T
V
E
S
S
A
A
S
H
K
L
Site 28
S435
T
V
E
S
S
A
A
S
H
K
L
L
R
K
I
Site 29
T463
E
K
R
P
E
L
L
T
N
E
D
L
Q
G
R
Site 30
S473
D
L
Q
G
R
K
V
S
L
L
L
G
E
P
F
Site 31
S484
G
E
P
F
F
T
T
S
L
L
P
W
H
N
L
Site 32
S532
R
D
L
W
R
I
R
S
P
C
G
D
C
E
G
Site 33
S558
R
A
L
D
F
R
E
S
R
E
A
E
P
H
P
Site 34
Y569
E
P
H
P
L
W
E
Y
P
C
R
S
L
S
E
Site 35
S575
E
Y
P
C
R
S
L
S
E
P
W
Q
I
L
T
Site 36
T582
S
E
P
W
Q
I
L
T
F
D
F
Q
Q
P
V
Site 37
T599
Q
P
L
C
A
E
G
T
V
E
L
R
R
P
G
Site 38
S608
E
L
R
R
P
G
Q
S
H
A
A
V
L
W
M
Site 39
T620
L
W
M
E
Y
H
L
T
P
E
C
T
L
S
T
Site 40
T624
Y
H
L
T
P
E
C
T
L
S
T
G
L
L
E
Site 41
Y650
P
H
C
K
Q
A
V
Y
F
F
S
P
A
P
D
Site 42
S653
K
Q
A
V
Y
F
F
S
P
A
P
D
P
R
A
Site 43
S669
L
G
G
P
R
T
V
S
Y
A
V
E
F
H
P
Site 44
Y670
G
G
P
R
T
V
S
Y
A
V
E
F
H
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation