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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBCCD1
Full Name:
TBCC domain-containing protein 1
Alias:
Type:
Mass (Da):
63530
Number AA:
557
UniProt ID:
Q9NVR7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
A
L
Q
V
P
P
P
S
K
F
S
L
H
Y
L
Site 2
S29
V
P
P
P
S
K
F
S
L
H
Y
L
R
K
I
Site 3
Y32
P
S
K
F
S
L
H
Y
L
R
K
I
S
T
Y
Site 4
S37
L
H
Y
L
R
K
I
S
T
Y
V
Q
I
R
A
Site 5
Y39
Y
L
R
K
I
S
T
Y
V
Q
I
R
A
T
E
Site 6
T45
T
Y
V
Q
I
R
A
T
E
G
A
Y
P
R
L
Site 7
Y49
I
R
A
T
E
G
A
Y
P
R
L
Y
W
S
T
Site 8
Y53
E
G
A
Y
P
R
L
Y
W
S
T
W
R
H
I
Site 9
S81
L
Y
F
E
I
F
D
S
L
S
M
K
T
P
E
Site 10
S83
F
E
I
F
D
S
L
S
M
K
T
P
E
E
R
Site 11
T86
F
D
S
L
S
M
K
T
P
E
E
R
L
E
W
Site 12
S94
P
E
E
R
L
E
W
S
E
V
L
S
N
C
M
Site 13
S98
L
E
W
S
E
V
L
S
N
C
M
S
E
E
E
Site 14
S102
E
V
L
S
N
C
M
S
E
E
E
V
E
K
Q
Site 15
S114
E
K
Q
R
N
Q
L
S
V
D
T
L
Q
F
L
Site 16
S137
N
K
V
S
L
R
T
S
L
I
G
E
E
W
P
Site 17
S145
L
I
G
E
E
W
P
S
P
R
N
K
S
Q
S
Site 18
S150
W
P
S
P
R
N
K
S
Q
S
P
D
L
T
E
Site 19
S152
S
P
R
N
K
S
Q
S
P
D
L
T
E
K
S
Site 20
T156
K
S
Q
S
P
D
L
T
E
K
S
N
C
H
N
Site 21
Y176
Y
S
H
Q
A
F
V
Y
D
H
L
S
D
L
L
Site 22
T193
L
L
D
P
K
Q
L
T
A
S
F
H
S
T
H
Site 23
S195
D
P
K
Q
L
T
A
S
F
H
S
T
H
S
S
Site 24
S198
Q
L
T
A
S
F
H
S
T
H
S
S
L
V
S
Site 25
T199
L
T
A
S
F
H
S
T
H
S
S
L
V
S
R
Site 26
S201
A
S
F
H
S
T
H
S
S
L
V
S
R
E
A
Site 27
S202
S
F
H
S
T
H
S
S
L
V
S
R
E
A
V
Site 28
S213
R
E
A
V
V
A
L
S
F
L
I
E
G
T
I
Site 29
T219
L
S
F
L
I
E
G
T
I
S
R
A
R
K
I
Site 30
S221
F
L
I
E
G
T
I
S
R
A
R
K
I
Y
P
Site 31
Y227
I
S
R
A
R
K
I
Y
P
L
H
E
L
A
L
Site 32
S242
W
Q
P
L
H
A
D
S
G
F
S
K
I
S
K
Site 33
S248
D
S
G
F
S
K
I
S
K
T
F
S
F
Y
K
Site 34
T250
G
F
S
K
I
S
K
T
F
S
F
Y
K
L
E
Site 35
S252
S
K
I
S
K
T
F
S
F
Y
K
L
E
T
W
Site 36
T265
T
W
L
R
S
C
L
T
G
N
P
F
G
T
S
Site 37
S272
T
G
N
P
F
G
T
S
A
C
L
K
S
G
K
Site 38
S277
G
T
S
A
C
L
K
S
G
K
K
L
A
W
A
Site 39
T319
M
S
Q
V
Y
K
Q
T
L
A
K
S
S
D
T
Site 40
S323
Y
K
Q
T
L
A
K
S
S
D
T
L
A
G
A
Site 41
T326
T
L
A
K
S
S
D
T
L
A
G
A
H
V
K
Site 42
S340
K
I
H
R
C
N
E
S
F
I
Y
L
L
S
P
Site 43
Y343
R
C
N
E
S
F
I
Y
L
L
S
P
L
R
S
Site 44
S350
Y
L
L
S
P
L
R
S
V
T
I
E
K
C
R
Site 45
T352
L
S
P
L
R
S
V
T
I
E
K
C
R
N
S
Site 46
S409
P
T
R
P
L
I
L
S
G
N
Q
T
V
T
F
Site 47
T415
L
S
G
N
Q
T
V
T
F
A
P
F
H
T
H
Site 48
S453
M
V
V
C
R
E
N
S
D
T
R
V
F
Q
L
Site 49
T455
V
C
R
E
N
S
D
T
R
V
F
Q
L
L
P
Site 50
T479
P
F
E
M
E
G
D
T
T
E
I
P
G
G
L
Site 51
T480
F
E
M
E
G
D
T
T
E
I
P
G
G
L
P
Site 52
S488
E
I
P
G
G
L
P
S
V
Y
Q
K
A
L
G
Site 53
Y490
P
G
G
L
P
S
V
Y
Q
K
A
L
G
Q
R
Site 54
T514
T
V
K
E
A
H
L
T
K
D
Q
R
K
Q
F
Site 55
S544
G
H
R
Q
Q
L
D
S
L
V
P
P
A
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation