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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PNPO
Full Name:
Pyridoxine-5'-phosphate oxidase
Alias:
PDXPO; pyridoxamine-phosphate oxidase
Type:
Oxidoreductase; Cofactor and Vitamin Metabolism - vitamin B6; EC 1.4.3.5
Mass (Da):
29988
Number AA:
261
UniProt ID:
Q9NVS9
International Prot ID:
IPI00018272
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0010181
GO:0004733
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0008615
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
W
L
R
G
V
T
A
T
F
G
R
P
A
E
W
Site 2
Y21
R
P
A
E
W
P
G
Y
L
S
H
L
C
G
R
Site 3
S23
A
E
W
P
G
Y
L
S
H
L
C
G
R
S
A
Site 4
S40
D
L
G
P
M
R
K
S
Y
R
G
D
R
E
A
Site 5
Y41
L
G
P
M
R
K
S
Y
R
G
D
R
E
A
F
Site 6
T54
A
F
E
E
T
H
L
T
S
L
D
P
V
K
Q
Site 7
S93
C
T
R
D
G
K
P
S
A
R
M
L
L
L
K
Site 8
T111
K
D
G
F
R
F
F
T
N
F
E
S
R
K
G
Site 9
S115
R
F
F
T
N
F
E
S
R
K
G
K
E
L
D
Site 10
S123
R
K
G
K
E
L
D
S
N
P
F
A
S
L
V
Site 11
S128
L
D
S
N
P
F
A
S
L
V
F
Y
W
E
P
Site 12
Y132
P
F
A
S
L
V
F
Y
W
E
P
L
N
R
Q
Site 13
Y157
P
E
E
E
A
E
C
Y
F
H
S
R
P
K
S
Site 14
S160
E
A
E
C
Y
F
H
S
R
P
K
S
S
Q
I
Site 15
S164
Y
F
H
S
R
P
K
S
S
Q
I
G
A
V
V
Site 16
S165
F
H
S
R
P
K
S
S
Q
I
G
A
V
V
S
Site 17
S176
A
V
V
S
H
Q
S
S
V
I
P
D
R
E
Y
Site 18
Y183
S
V
I
P
D
R
E
Y
L
R
K
K
N
E
E
Site 19
Y195
N
E
E
L
E
Q
L
Y
Q
D
Q
E
V
P
K
Site 20
S205
Q
E
V
P
K
P
K
S
W
G
G
Y
V
L
Y
Site 21
Y209
K
P
K
S
W
G
G
Y
V
L
Y
P
Q
V
M
Site 22
Y212
S
W
G
G
Y
V
L
Y
P
Q
V
M
E
F
W
Site 23
T238
V
F
R
R
G
L
P
T
G
D
S
P
L
G
P
Site 24
S241
R
G
L
P
T
G
D
S
P
L
G
P
M
T
H
Site 25
T247
D
S
P
L
G
P
M
T
H
R
G
E
E
D
W
Site 26
Y256
R
G
E
E
D
W
L
Y
E
R
L
A
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation