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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTPAP
Full Name:
Poly(A) RNA polymerase, mitochondrial
Alias:
PAP-associated domain-containing protein 1;Polynucleotide adenylyltransferase;Terminal uridylyltransferase 1;mtPAP
Type:
Mass (Da):
66172
Number AA:
582
UniProt ID:
Q9NVV4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
N
L
C
A
R
R
R
T
R
V
Q
R
P
I
V
Site 2
T35
R
L
L
S
C
P
G
T
V
A
K
D
L
R
R
Site 3
S47
L
R
R
D
E
Q
P
S
G
S
V
E
T
G
F
Site 4
S49
R
D
E
Q
P
S
G
S
V
E
T
G
F
E
D
Site 5
S64
K
I
P
K
R
R
F
S
E
M
Q
N
E
R
R
Site 6
Y94
S
E
N
K
F
L
K
Y
L
S
Q
F
G
P
I
Site 7
S96
N
K
F
L
K
Y
L
S
Q
F
G
P
I
N
N
Site 8
Y107
P
I
N
N
H
F
F
Y
E
S
F
G
L
Y
A
Site 9
S126
C
Q
K
E
S
I
G
S
L
Q
N
G
T
H
T
Site 10
T131
I
G
S
L
Q
N
G
T
H
T
P
S
T
A
M
Site 11
T133
S
L
Q
N
G
T
H
T
P
S
T
A
M
E
T
Site 12
S135
Q
N
G
T
H
T
P
S
T
A
M
E
T
A
I
Site 13
T140
T
P
S
T
A
M
E
T
A
I
P
F
R
S
R
Site 14
S158
L
K
L
K
N
Q
T
S
E
R
S
R
V
R
S
Site 15
S161
K
N
Q
T
S
E
R
S
R
V
R
S
S
N
Q
Site 16
S165
S
E
R
S
R
V
R
S
S
N
Q
L
P
R
S
Site 17
S166
E
R
S
R
V
R
S
S
N
Q
L
P
R
S
N
Site 18
S172
S
S
N
Q
L
P
R
S
N
K
Q
L
F
E
L
Site 19
Y182
Q
L
F
E
L
L
C
Y
A
E
S
I
D
D
Q
Site 20
S185
E
L
L
C
Y
A
E
S
I
D
D
Q
L
N
T
Site 21
T192
S
I
D
D
Q
L
N
T
L
L
K
E
F
Q
L
Site 22
T200
L
L
K
E
F
Q
L
T
E
E
N
T
K
L
R
Site 23
Y208
E
E
N
T
K
L
R
Y
L
T
C
S
L
I
E
Site 24
T210
N
T
K
L
R
Y
L
T
C
S
L
I
E
D
M
Site 25
T236
P
F
G
S
S
V
N
T
F
G
K
L
G
C
D
Site 26
T253
M
F
L
D
L
D
E
T
R
N
L
S
A
H
K
Site 27
S257
L
D
E
T
R
N
L
S
A
H
K
I
S
G
N
Site 28
S276
F
Q
V
K
N
V
P
S
E
R
I
A
T
Q
K
Site 29
S316
R
C
P
L
V
R
F
S
H
Q
A
S
G
F
Q
Site 30
S320
V
R
F
S
H
Q
A
S
G
F
Q
C
D
L
T
Site 31
T327
S
G
F
Q
C
D
L
T
T
N
N
R
I
A
L
Site 32
T328
G
F
Q
C
D
L
T
T
N
N
R
I
A
L
T
Site 33
S365
R
C
W
A
R
A
H
S
L
T
S
S
I
P
G
Site 34
T367
W
A
R
A
H
S
L
T
S
S
I
P
G
A
W
Site 35
S369
R
A
H
S
L
T
S
S
I
P
G
A
W
I
T
Site 36
T398
R
S
P
P
I
L
P
T
L
D
S
L
K
T
L
Site 37
T404
P
T
L
D
S
L
K
T
L
A
D
A
E
D
K
Site 38
T420
V
I
E
G
N
N
C
T
F
V
R
D
L
S
R
Site 39
S426
C
T
F
V
R
D
L
S
R
I
K
P
S
Q
N
Site 40
S431
D
L
S
R
I
K
P
S
Q
N
T
E
T
L
E
Site 41
S471
R
E
Q
N
K
P
D
S
S
P
L
Y
I
Q
N
Site 42
S472
E
Q
N
K
P
D
S
S
P
L
Y
I
Q
N
P
Site 43
Y475
K
P
D
S
S
P
L
Y
I
Q
N
P
F
E
T
Site 44
S483
I
Q
N
P
F
E
T
S
L
N
I
S
K
N
V
Site 45
S487
F
E
T
S
L
N
I
S
K
N
V
S
Q
S
Q
Site 46
S491
L
N
I
S
K
N
V
S
Q
S
Q
L
Q
K
F
Site 47
S493
I
S
K
N
V
S
Q
S
Q
L
Q
K
F
V
D
Site 48
S505
F
V
D
L
A
R
E
S
A
W
I
L
Q
Q
E
Site 49
T514
W
I
L
Q
Q
E
D
T
D
R
P
S
I
S
S
Site 50
S518
Q
E
D
T
D
R
P
S
I
S
S
N
R
P
W
Site 51
S521
T
D
R
P
S
I
S
S
N
R
P
W
G
L
V
Site 52
S540
P
S
A
P
N
R
K
S
F
T
K
K
K
S
N
Site 53
T542
A
P
N
R
K
S
F
T
K
K
K
S
N
K
F
Site 54
S546
K
S
F
T
K
K
K
S
N
K
F
A
I
E
T
Site 55
T553
S
N
K
F
A
I
E
T
V
K
N
L
L
E
S
Site 56
T566
E
S
L
K
G
N
R
T
E
N
F
T
K
T
S
Site 57
T570
G
N
R
T
E
N
F
T
K
T
S
G
K
R
T
Site 58
T572
R
T
E
N
F
T
K
T
S
G
K
R
T
I
S
Site 59
T577
T
K
T
S
G
K
R
T
I
S
T
Q
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation