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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NECAP2
Full Name:
Adaptin ear-binding coat-associated protein 2
Alias:
Adaptin ear-binding coat-associated 2; FLJ10420; NECAP endocytosis associated 2; NECAP endocytosis-associated protein 2; NECP2
Type:
Vesicle protein
Mass (Da):
28339
Number AA:
263
UniProt ID:
Q9NVZ3
International Prot ID:
IPI00018188
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030125
GO:0005905
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006897
GO:0015031
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
E
E
S
G
Y
E
S
V
L
C
V
K
Site 2
S8
M
E
E
S
G
Y
E
S
V
L
C
V
K
P
D
Site 3
Y19
V
K
P
D
V
H
V
Y
R
I
P
P
R
A
T
Site 4
T26
Y
R
I
P
P
R
A
T
N
R
G
Y
R
A
A
Site 5
Y30
P
R
A
T
N
R
G
Y
R
A
A
E
W
Q
L
Site 6
S41
E
W
Q
L
D
Q
P
S
W
S
G
R
L
R
I
Site 7
S43
Q
L
D
Q
P
S
W
S
G
R
L
R
I
T
A
Site 8
T49
W
S
G
R
L
R
I
T
A
K
G
Q
M
A
Y
Site 9
S64
I
K
L
E
D
R
T
S
G
E
L
F
A
Q
A
Site 10
T79
P
V
D
Q
F
P
G
T
A
V
E
S
V
T
D
Site 11
S83
F
P
G
T
A
V
E
S
V
T
D
S
S
R
Y
Site 12
S87
A
V
E
S
V
T
D
S
S
R
Y
F
V
I
R
Site 13
Y90
S
V
T
D
S
S
R
Y
F
V
I
R
I
E
D
Site 14
S181
N
P
R
V
R
P
A
S
T
G
G
L
S
L
L
Site 15
T182
P
R
V
R
P
A
S
T
G
G
L
S
L
L
P
Site 16
S186
P
A
S
T
G
G
L
S
L
L
P
P
P
P
G
Site 17
T196
P
P
P
P
G
G
K
T
S
T
L
I
P
P
P
Site 18
S197
P
P
P
G
G
K
T
S
T
L
I
P
P
P
G
Site 19
T198
P
P
G
G
K
T
S
T
L
I
P
P
P
G
E
Site 20
S222
Q
P
A
V
A
P
S
S
G
G
A
P
V
P
W
Site 21
T244
A
D
I
W
G
D
F
T
K
S
T
G
S
T
S
Site 22
S246
I
W
G
D
F
T
K
S
T
G
S
T
S
S
Q
Site 23
T247
W
G
D
F
T
K
S
T
G
S
T
S
S
Q
T
Site 24
S249
D
F
T
K
S
T
G
S
T
S
S
Q
T
Q
P
Site 25
S252
K
S
T
G
S
T
S
S
Q
T
Q
P
G
T
G
Site 26
T254
T
G
S
T
S
S
Q
T
Q
P
G
T
G
W
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation