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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF358
Full Name:
Zinc finger protein 358
Alias:
ZFEND; ZN358
Type:
Transcription factor
Mass (Da):
59287
Number AA:
568
UniProt ID:
Q9NW07
International Prot ID:
IPI00646336
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
R
R
S
V
L
V
R
N
P
G
Site 2
Y19
H
K
G
L
R
P
V
Y
E
E
L
D
S
D
S
Site 3
S24
P
V
Y
E
E
L
D
S
D
S
E
D
L
D
P
Site 4
S26
Y
E
E
L
D
S
D
S
E
D
L
D
P
N
P
Site 5
S40
P
E
D
L
D
P
V
S
E
D
P
E
P
D
P
Site 6
T52
P
D
P
E
D
L
N
T
V
P
E
D
V
D
P
Site 7
S60
V
P
E
D
V
D
P
S
Y
E
D
L
E
P
V
Site 8
Y61
P
E
D
V
D
P
S
Y
E
D
L
E
P
V
S
Site 9
S68
Y
E
D
L
E
P
V
S
E
D
L
D
P
D
A
Site 10
S80
P
D
A
E
A
P
G
S
E
P
Q
D
P
D
P
Site 11
S89
P
Q
D
P
D
P
M
S
S
S
F
D
L
D
P
Site 12
S90
Q
D
P
D
P
M
S
S
S
F
D
L
D
P
D
Site 13
S91
D
P
D
P
M
S
S
S
F
D
L
D
P
D
V
Site 14
S110
P
L
I
L
D
P
N
S
D
T
L
S
P
G
D
Site 15
T112
I
L
D
P
N
S
D
T
L
S
P
G
D
P
K
Site 16
S114
D
P
N
S
D
T
L
S
P
G
D
P
K
V
D
Site 17
S124
D
P
K
V
D
P
I
S
S
G
L
T
A
T
P
Site 18
S152
A
S
P
P
R
P
F
S
C
P
D
C
G
R
A
Site 19
S163
C
G
R
A
F
R
R
S
S
G
L
S
Q
H
R
Site 20
S164
G
R
A
F
R
R
S
S
G
L
S
Q
H
R
R
Site 21
S167
F
R
R
S
S
G
L
S
Q
H
R
R
T
H
S
Site 22
T172
G
L
S
Q
H
R
R
T
H
S
G
E
K
P
Y
Site 23
S174
S
Q
H
R
R
T
H
S
G
E
K
P
Y
R
C
Site 24
Y179
T
H
S
G
E
K
P
Y
R
C
P
D
C
G
K
Site 25
S187
R
C
P
D
C
G
K
S
F
S
H
G
A
T
L
Site 26
S189
P
D
C
G
K
S
F
S
H
G
A
T
L
A
Q
Site 27
T193
K
S
F
S
H
G
A
T
L
A
Q
H
R
G
I
Site 28
Y207
I
H
T
G
A
R
P
Y
Q
C
A
A
C
G
K
Site 29
S220
G
K
A
F
G
W
R
S
T
L
L
K
H
R
S
Site 30
T221
K
A
F
G
W
R
S
T
L
L
K
H
R
S
S
Site 31
S227
S
T
L
L
K
H
R
S
S
H
S
G
E
K
P
Site 32
S228
T
L
L
K
H
R
S
S
H
S
G
E
K
P
H
Site 33
S230
L
K
H
R
S
S
H
S
G
E
K
P
H
H
C
Site 34
S248
G
K
A
F
G
H
G
S
L
L
A
Q
H
L
R
Site 35
T284
A
L
L
K
H
L
R
T
H
T
G
E
R
P
Y
Site 36
T286
L
K
H
L
R
T
H
T
G
E
R
P
Y
P
C
Site 37
Y291
T
H
T
G
E
R
P
Y
P
C
P
Q
C
G
K
Site 38
S304
G
K
A
F
G
Q
S
S
A
L
L
Q
H
Q
R
Site 39
T314
L
Q
H
Q
R
T
H
T
A
E
R
P
Y
R
C
Site 40
Y319
T
H
T
A
E
R
P
Y
R
C
P
H
C
G
K
Site 41
S332
G
K
A
F
G
Q
S
S
N
L
Q
H
H
L
R
Site 42
T342
Q
H
H
L
R
I
H
T
G
E
R
P
Y
A
C
Site 43
Y347
I
H
T
G
E
R
P
Y
A
C
P
H
C
S
K
Site 44
S360
S
K
A
F
G
Q
S
S
A
L
L
Q
H
L
H
Site 45
S370
L
Q
H
L
H
V
H
S
G
E
R
P
Y
R
C
Site 46
Y375
V
H
S
G
E
R
P
Y
R
C
Q
L
C
G
K
Site 47
S388
G
K
A
F
G
Q
A
S
S
L
T
K
H
K
R
Site 48
S389
K
A
F
G
Q
A
S
S
L
T
K
H
K
R
V
Site 49
S428
G
P
G
L
S
P
A
S
M
M
R
P
G
Q
V
Site 50
S453
L
G
S
G
L
G
L
S
P
G
T
S
S
G
R
Site 51
S457
L
G
L
S
P
G
T
S
S
G
R
N
P
D
P
Site 52
S458
G
L
S
P
G
T
S
S
G
R
N
P
D
P
G
Site 53
S466
G
R
N
P
D
P
G
S
G
P
G
T
L
P
D
Site 54
T470
D
P
G
S
G
P
G
T
L
P
D
P
S
S
K
Site 55
S475
P
G
T
L
P
D
P
S
S
K
P
L
P
G
S
Site 56
S476
G
T
L
P
D
P
S
S
K
P
L
P
G
S
R
Site 57
S482
S
S
K
P
L
P
G
S
R
S
T
P
S
P
T
Site 58
S484
K
P
L
P
G
S
R
S
T
P
S
P
T
P
V
Site 59
T485
P
L
P
G
S
R
S
T
P
S
P
T
P
V
E
Site 60
S487
P
G
S
R
S
T
P
S
P
T
P
V
E
S
S
Site 61
T489
S
R
S
T
P
S
P
T
P
V
E
S
S
D
P
Site 62
S493
P
S
P
T
P
V
E
S
S
D
P
K
A
G
H
Site 63
S494
S
P
T
P
V
E
S
S
D
P
K
A
G
H
D
Site 64
S509
A
G
P
D
L
V
P
S
P
D
L
D
P
V
P
Site 65
S517
P
D
L
D
P
V
P
S
P
D
P
D
P
V
P
Site 66
S525
P
D
P
D
P
V
P
S
P
D
P
N
P
V
S
Site 67
S532
S
P
D
P
N
P
V
S
C
P
D
P
C
S
P
Site 68
S538
V
S
C
P
D
P
C
S
P
T
R
G
T
V
S
Site 69
T543
P
C
S
P
T
R
G
T
V
S
P
A
L
P
T
Site 70
S545
S
P
T
R
G
T
V
S
P
A
L
P
T
G
E
Site 71
S553
P
A
L
P
T
G
E
S
P
E
W
V
Q
E
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation