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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR70
Full Name:
WD repeat-containing protein 70
Alias:
FLJ10233; LOC55100; WD repeat 70; WD repeat domain 70
Type:
Unknown function
Mass (Da):
73201
Number AA:
654
UniProt ID:
Q9NW82
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
P
S
E
V
T
G
S
D
A
S
G
P
D
P
Site 2
T36
G
F
G
K
K
A
R
T
F
D
L
E
A
M
F
Site 3
T49
M
F
E
Q
T
R
R
T
A
V
E
R
S
R
K
Site 4
T57
A
V
E
R
S
R
K
T
L
E
A
R
E
K
E
Site 5
T83
Q
N
E
D
I
E
P
T
S
S
R
S
N
V
V
Site 6
S84
N
E
D
I
E
P
T
S
S
R
S
N
V
V
R
Site 7
S85
E
D
I
E
P
T
S
S
R
S
N
V
V
R
D
Site 8
S94
S
N
V
V
R
D
C
S
K
S
S
S
R
D
T
Site 9
S96
V
V
R
D
C
S
K
S
S
S
R
D
T
S
S
Site 10
S97
V
R
D
C
S
K
S
S
S
R
D
T
S
S
S
Site 11
S98
R
D
C
S
K
S
S
S
R
D
T
S
S
S
E
Site 12
T101
S
K
S
S
S
R
D
T
S
S
S
E
S
E
Q
Site 13
S102
K
S
S
S
R
D
T
S
S
S
E
S
E
Q
S
Site 14
S103
S
S
S
R
D
T
S
S
S
E
S
E
Q
S
S
Site 15
S104
S
S
R
D
T
S
S
S
E
S
E
Q
S
S
D
Site 16
S106
R
D
T
S
S
S
E
S
E
Q
S
S
D
S
S
Site 17
S109
S
S
S
E
S
E
Q
S
S
D
S
S
D
D
E
Site 18
S110
S
S
E
S
E
Q
S
S
D
S
S
D
D
E
L
Site 19
S112
E
S
E
Q
S
S
D
S
S
D
D
E
L
I
G
Site 20
S113
S
E
Q
S
S
D
S
S
D
D
E
L
I
G
P
Site 21
S173
P
V
H
K
I
P
D
S
H
E
I
T
L
K
H
Site 22
T177
I
P
D
S
H
E
I
T
L
K
H
G
T
K
T
Site 23
T184
T
L
K
H
G
T
K
T
V
S
A
L
G
L
D
Site 24
S186
K
H
G
T
K
T
V
S
A
L
G
L
D
P
S
Site 25
T199
P
S
G
A
R
L
V
T
G
G
Y
D
Y
D
V
Site 26
Y202
A
R
L
V
T
G
G
Y
D
Y
D
V
K
F
W
Site 27
Y204
L
V
T
G
G
Y
D
Y
D
V
K
F
W
D
F
Site 28
S217
D
F
A
G
M
D
A
S
F
K
A
F
R
S
L
Site 29
S223
A
S
F
K
A
F
R
S
L
Q
P
C
E
C
H
Site 30
S238
Q
I
K
S
L
Q
Y
S
N
T
G
D
M
I
L
Site 31
Y272
E
C
I
K
G
D
Q
Y
I
V
D
M
A
N
T
Site 32
S303
K
G
E
F
M
T
C
S
N
D
A
T
V
R
T
Site 33
S321
E
N
P
K
K
Q
K
S
V
F
K
P
R
T
M
Site 34
T327
K
S
V
F
K
P
R
T
M
Q
G
K
K
V
I
Site 35
T337
G
K
K
V
I
P
T
T
C
T
Y
S
R
D
G
Site 36
Y340
V
I
P
T
T
C
T
Y
S
R
D
G
N
L
I
Site 37
Y371
T
V
H
P
K
F
H
Y
K
Q
A
H
D
S
G
Site 38
S377
H
Y
K
Q
A
H
D
S
G
T
D
T
S
C
V
Site 39
T379
K
Q
A
H
D
S
G
T
D
T
S
C
V
T
F
Site 40
T381
A
H
D
S
G
T
D
T
S
C
V
T
F
S
Y
Site 41
S382
H
D
S
G
T
D
T
S
C
V
T
F
S
Y
D
Site 42
T385
G
T
D
T
S
C
V
T
F
S
Y
D
G
N
V
Site 43
S401
A
S
R
G
G
D
D
S
L
K
L
W
D
I
R
Site 44
S416
Q
F
N
K
P
L
F
S
A
S
G
L
P
T
M
Site 45
S418
N
K
P
L
F
S
A
S
G
L
P
T
M
F
P
Site 46
T460
L
V
F
F
E
R
R
T
F
Q
R
V
Y
E
I
Site 47
Y465
R
R
T
F
Q
R
V
Y
E
I
D
I
T
D
A
Site 48
Y498
G
N
G
L
A
K
V
Y
Y
D
P
N
K
S
Q
Site 49
Y499
N
G
L
A
K
V
Y
Y
D
P
N
K
S
Q
R
Site 50
S504
V
Y
Y
D
P
N
K
S
Q
R
G
A
K
L
C
Site 51
T515
A
K
L
C
V
V
K
T
Q
R
K
A
K
Q
A
Site 52
S546
F
R
E
P
R
Q
R
S
T
R
K
Q
L
E
K
Site 53
T547
R
E
P
R
Q
R
S
T
R
K
Q
L
E
K
D
Site 54
S561
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Site 55
T579
G
R
G
G
R
V
G
T
H
G
G
T
L
S
S
Site 56
T583
R
V
G
T
H
G
G
T
L
S
S
Y
I
V
K
Site 57
S585
G
T
H
G
G
T
L
S
S
Y
I
V
K
N
I
Site 58
T597
K
N
I
A
L
D
K
T
D
D
S
N
P
R
E
Site 59
S600
A
L
D
K
T
D
D
S
N
P
R
E
A
I
L
Site 60
S616
H
A
K
A
A
E
D
S
P
Y
W
V
S
P
A
Site 61
Y618
K
A
A
E
D
S
P
Y
W
V
S
P
A
Y
S
Site 62
S621
E
D
S
P
Y
W
V
S
P
A
Y
S
K
T
Q
Site 63
Y624
P
Y
W
V
S
P
A
Y
S
K
T
Q
P
K
T
Site 64
S625
Y
W
V
S
P
A
Y
S
K
T
Q
P
K
T
M
Site 65
T627
V
S
P
A
Y
S
K
T
Q
P
K
T
M
F
A
Site 66
T631
Y
S
K
T
Q
P
K
T
M
F
A
Q
V
E
S
Site 67
S638
T
M
F
A
Q
V
E
S
D
D
E
E
A
K
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation