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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLTM
Full Name:
SAFB-like transcription modulator
Alias:
FLJ10005; FLJ13213; Met; Modulator of estrogen induced transcription; SAFB-like transcription modulator: Modulator of estrogen-induced transcription: cDNA FLJ30633 fis, clone CTONG2002418, highly similar to Homo sapiens modulator of estrogen induced transcription, transcript variant 1, mRNA: cDNA FLJ78261; SAFB-like, transcription modulator
Type:
Transcription, coactivator/corepressor
Mass (Da):
117148
Number AA:
1034
UniProt ID:
Q9NWH9
International Prot ID:
IPI00019996
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
A
A
A
T
G
A
V
A
A
S
A
Site 2
S11
A
T
G
A
V
A
A
S
A
A
S
G
Q
A
E
Site 3
S14
A
V
A
A
S
A
A
S
G
Q
A
E
G
K
K
Site 4
S32
L
R
V
I
D
L
K
S
E
L
K
R
R
N
L
Site 5
T42
K
R
R
N
L
D
I
T
G
V
K
T
V
L
I
Site 6
T69
D
P
D
N
I
E
L
T
V
S
T
D
T
P
N
Site 7
S71
D
N
I
E
L
T
V
S
T
D
T
P
N
K
K
Site 8
T72
N
I
E
L
T
V
S
T
D
T
P
N
K
K
P
Site 9
T74
E
L
T
V
S
T
D
T
P
N
K
K
P
T
K
Site 10
T80
D
T
P
N
K
K
P
T
K
G
K
G
K
K
H
Site 11
S93
K
H
E
A
D
E
L
S
G
D
A
S
V
E
D
Site 12
S97
D
E
L
S
G
D
A
S
V
E
D
D
A
F
I
Site 13
S126
G
N
D
E
L
K
D
S
E
E
F
G
E
N
E
Site 14
S139
N
E
E
E
N
V
H
S
K
E
L
L
S
A
E
Site 15
S144
V
H
S
K
E
L
L
S
A
E
E
N
K
R
A
Site 16
S170
I
E
K
E
D
I
E
S
Q
E
I
E
A
Q
E
Site 17
T182
A
Q
E
G
E
D
D
T
F
L
T
A
Q
D
G
Site 18
T205
I
A
G
S
G
D
G
T
Q
E
V
S
K
P
L
Site 19
S214
E
V
S
K
P
L
P
S
E
G
S
L
A
E
A
Site 20
S217
K
P
L
P
S
E
G
S
L
A
E
A
D
H
T
Site 21
T224
S
L
A
E
A
D
H
T
A
H
E
E
M
E
A
Site 22
T234
E
E
M
E
A
H
T
T
V
K
E
A
E
D
D
Site 23
S244
E
A
E
D
D
N
I
S
V
T
I
Q
A
E
D
Site 24
T254
I
Q
A
E
D
A
I
T
L
D
F
D
G
D
D
Site 25
S274
K
N
V
K
I
T
D
S
E
A
S
K
P
K
D
Site 26
S289
G
Q
D
A
I
A
Q
S
P
E
K
E
S
K
D
Site 27
S294
A
Q
S
P
E
K
E
S
K
D
Y
E
M
N
A
Site 28
Y297
P
E
K
E
S
K
D
Y
E
M
N
A
N
H
K
Site 29
S324
V
E
K
E
A
R
E
S
S
K
K
A
E
S
G
Site 30
S325
E
K
E
A
R
E
S
S
K
K
A
E
S
G
D
Site 31
T337
S
G
D
K
E
K
D
T
L
K
K
G
P
S
S
Site 32
S343
D
T
L
K
K
G
P
S
S
T
G
A
S
G
Q
Site 33
S344
T
L
K
K
G
P
S
S
T
G
A
S
G
Q
A
Site 34
T345
L
K
K
G
P
S
S
T
G
A
S
G
Q
A
K
Site 35
S348
G
P
S
S
T
G
A
S
G
Q
A
K
S
S
S
Site 36
S353
G
A
S
G
Q
A
K
S
S
S
K
E
S
K
D
Site 37
S354
A
S
G
Q
A
K
S
S
S
K
E
S
K
D
S
Site 38
S355
S
G
Q
A
K
S
S
S
K
E
S
K
D
S
K
Site 39
S358
A
K
S
S
S
K
E
S
K
D
S
K
T
S
S
Site 40
S361
S
S
K
E
S
K
D
S
K
T
S
S
K
D
D
Site 41
T363
K
E
S
K
D
S
K
T
S
S
K
D
D
K
G
Site 42
S365
S
K
D
S
K
T
S
S
K
D
D
K
G
S
T
Site 43
S371
S
S
K
D
D
K
G
S
T
S
S
T
S
G
S
Site 44
T372
S
K
D
D
K
G
S
T
S
S
T
S
G
S
S
Site 45
S373
K
D
D
K
G
S
T
S
S
T
S
G
S
S
G
Site 46
S374
D
D
K
G
S
T
S
S
T
S
G
S
S
G
S
Site 47
T375
D
K
G
S
T
S
S
T
S
G
S
S
G
S
S
Site 48
S376
K
G
S
T
S
S
T
S
G
S
S
G
S
S
T
Site 49
S378
S
T
S
S
T
S
G
S
S
G
S
S
T
K
N
Site 50
S382
T
S
G
S
S
G
S
S
T
K
N
I
W
V
S
Site 51
T383
S
G
S
S
G
S
S
T
K
N
I
W
V
S
G
Site 52
S389
S
T
K
N
I
W
V
S
G
L
S
S
N
T
K
Site 53
Y407
L
K
N
L
F
G
K
Y
G
K
V
L
S
A
K
Site 54
S412
G
K
Y
G
K
V
L
S
A
K
V
V
T
N
A
Site 55
T417
V
L
S
A
K
V
V
T
N
A
R
S
P
G
A
Site 56
S421
K
V
V
T
N
A
R
S
P
G
A
K
C
Y
G
Site 57
Y427
R
S
P
G
A
K
C
Y
G
I
V
T
M
S
S
Site 58
S433
C
Y
G
I
V
T
M
S
S
S
T
E
V
S
R
Site 59
S434
Y
G
I
V
T
M
S
S
S
T
E
V
S
R
C
Site 60
T436
I
V
T
M
S
S
S
T
E
V
S
R
C
I
A
Site 61
S439
M
S
S
S
T
E
V
S
R
C
I
A
H
L
H
Site 62
S456
E
L
H
G
Q
L
I
S
V
E
K
V
K
G
D
Site 63
S477
K
K
E
N
D
E
K
S
S
S
R
S
S
G
D
Site 64
S478
K
E
N
D
E
K
S
S
S
R
S
S
G
D
K
Site 65
S479
E
N
D
E
K
S
S
S
R
S
S
G
D
K
K
Site 66
S481
D
E
K
S
S
S
R
S
S
G
D
K
K
N
T
Site 67
S482
E
K
S
S
S
R
S
S
G
D
K
K
N
T
S
Site 68
T488
S
S
G
D
K
K
N
T
S
D
R
S
S
K
T
Site 69
S489
S
G
D
K
K
N
T
S
D
R
S
S
K
T
Q
Site 70
S493
K
N
T
S
D
R
S
S
K
T
Q
A
S
V
K
Site 71
S498
R
S
S
K
T
Q
A
S
V
K
K
E
E
K
R
Site 72
S506
V
K
K
E
E
K
R
S
S
E
K
S
E
K
K
Site 73
S507
K
K
E
E
K
R
S
S
E
K
S
E
K
K
E
Site 74
S510
E
K
R
S
S
E
K
S
E
K
K
E
S
K
D
Site 75
S515
E
K
S
E
K
K
E
S
K
D
T
K
K
I
E
Site 76
T518
D
N
G
A
S
G
Q
T
S
E
S
I
K
K
S
Site 77
S533
E
K
N
D
N
G
A
S
G
Q
T
S
E
S
I
Site 78
T536
D
N
G
A
S
G
Q
T
S
E
S
I
K
K
S
Site 79
S537
N
G
A
S
G
Q
T
S
E
S
I
K
K
S
E
Site 80
S539
A
S
G
Q
T
S
E
S
I
K
K
S
E
E
K
Site 81
S543
T
S
E
S
I
K
K
S
E
E
K
K
R
I
S
Site 82
S550
S
E
E
K
K
R
I
S
S
K
S
P
G
H
M
Site 83
S551
E
E
K
K
R
I
S
S
K
S
P
G
H
M
V
Site 84
S553
K
K
R
I
S
S
K
S
P
G
H
M
V
I
L
Site 85
T563
H
M
V
I
L
D
Q
T
K
G
D
H
C
R
P
Site 86
S571
K
G
D
H
C
R
P
S
R
R
G
R
Y
E
K
Site 87
Y576
R
P
S
R
R
G
R
Y
E
K
I
H
G
R
S
Site 88
S583
Y
E
K
I
H
G
R
S
K
E
K
E
R
A
S
Site 89
S590
S
K
E
K
E
R
A
S
L
D
K
K
R
D
K
Site 90
Y599
D
K
K
R
D
K
D
Y
R
R
K
E
I
L
P
Site 91
S725
Y
E
Q
E
K
R
N
S
L
K
R
P
R
D
V
Site 92
Y740
D
H
R
R
D
D
P
Y
W
S
E
N
K
K
L
Site 93
S742
R
R
D
D
P
Y
W
S
E
N
K
K
L
S
L
Site 94
S748
W
S
E
N
K
K
L
S
L
D
T
D
A
R
F
Site 95
T751
N
K
K
L
S
L
D
T
D
A
R
F
G
H
G
Site 96
S759
D
A
R
F
G
H
G
S
D
Y
S
R
Q
Q
N
Site 97
Y761
R
F
G
H
G
S
D
Y
S
R
Q
Q
N
R
F
Site 98
S782
E
R
G
R
F
P
E
S
S
A
V
Q
S
S
S
Site 99
S783
R
G
R
F
P
E
S
S
A
V
Q
S
S
S
F
Site 100
S787
P
E
S
S
A
V
Q
S
S
S
F
E
R
R
D
Site 101
S789
S
S
A
V
Q
S
S
S
F
E
R
R
D
R
F
Site 102
S800
R
D
R
F
V
G
Q
S
E
G
K
K
A
R
P
Site 103
T808
E
G
K
K
A
R
P
T
A
R
R
E
D
P
S
Site 104
S815
T
A
R
R
E
D
P
S
F
E
R
Y
P
K
N
Site 105
Y819
E
D
P
S
F
E
R
Y
P
K
N
F
S
D
S
Site 106
S824
E
R
Y
P
K
N
F
S
D
S
R
R
N
E
P
Site 107
S826
Y
P
K
N
F
S
D
S
R
R
N
E
P
P
P
Site 108
S841
P
R
N
E
L
R
E
S
D
R
R
E
V
R
G
Site 109
T855
G
E
R
D
E
R
R
T
V
I
I
H
D
R
P
Site 110
T865
I
H
D
R
P
D
I
T
H
P
R
H
P
R
E
Site 111
S878
R
E
A
G
P
N
P
S
R
P
T
S
W
K
S
Site 112
T881
G
P
N
P
S
R
P
T
S
W
K
S
E
G
S
Site 113
S882
P
N
P
S
R
P
T
S
W
K
S
E
G
S
M
Site 114
S885
S
R
P
T
S
W
K
S
E
G
S
M
S
T
D
Site 115
S890
W
K
S
E
G
S
M
S
T
D
K
R
E
T
R
Site 116
T896
M
S
T
D
K
R
E
T
R
V
E
R
P
E
R
Site 117
S904
R
V
E
R
P
E
R
S
G
R
E
V
S
G
H
Site 118
S909
E
R
S
G
R
E
V
S
G
H
S
V
R
G
A
Site 119
S912
G
R
E
V
S
G
H
S
V
R
G
A
P
P
G
Site 120
S922
G
A
P
P
G
N
R
S
S
A
S
G
Y
G
S
Site 121
S923
A
P
P
G
N
R
S
S
A
S
G
Y
G
S
R
Site 122
S925
P
G
N
R
S
S
A
S
G
Y
G
S
R
E
G
Site 123
Y927
N
R
S
S
A
S
G
Y
G
S
R
E
G
D
R
Site 124
S929
S
S
A
S
G
Y
G
S
R
E
G
D
R
G
V
Site 125
T938
E
G
D
R
G
V
I
T
D
R
G
G
G
S
Q
Site 126
S944
I
T
D
R
G
G
G
S
Q
H
Y
P
E
E
R
Site 127
Y947
R
G
G
G
S
Q
H
Y
P
E
E
R
H
V
V
Site 128
T961
V
E
R
H
G
R
D
T
S
G
P
R
K
E
W
Site 129
S962
E
R
H
G
R
D
T
S
G
P
R
K
E
W
H
Site 130
S973
K
E
W
H
G
P
P
S
Q
G
P
S
Y
H
D
Site 131
S977
G
P
P
S
Q
G
P
S
Y
H
D
T
R
R
M
Site 132
Y978
P
P
S
Q
G
P
S
Y
H
D
T
R
R
M
G
Site 133
T981
Q
G
P
S
Y
H
D
T
R
R
M
G
D
G
R
Site 134
T995
R
A
G
A
G
M
I
T
Q
H
S
S
N
A
S
Site 135
S998
A
G
M
I
T
Q
H
S
S
N
A
S
P
I
N
Site 136
S999
G
M
I
T
Q
H
S
S
N
A
S
P
I
N
R
Site 137
S1002
T
Q
H
S
S
N
A
S
P
I
N
R
I
V
Q
Site 138
S1011
I
N
R
I
V
Q
I
S
G
N
S
M
P
R
G
Site 139
S1014
I
V
Q
I
S
G
N
S
M
P
R
G
S
G
S
Site 140
S1019
G
N
S
M
P
R
G
S
G
S
G
F
K
P
F
Site 141
S1021
S
M
P
R
G
S
G
S
G
F
K
P
F
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation