KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ASNSD1
Full Name:
Asparagine synthetase domain-containing protein 1
Alias:
HCV NS3-transactivated protein 1
Type:
Mass (Da):
72161
Number AA:
643
UniProt ID:
Q9NWL6
International Prot ID:
IPI00005084
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004066
GO:0016874
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006519
GO:0006520
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
D
L
K
E
D
L
L
Y
N
L
K
Q
R
G
P
Site 2
S34
L
K
Q
R
G
P
N
S
S
K
Q
L
L
K
S
Site 3
S35
K
Q
R
G
P
N
S
S
K
Q
L
L
K
S
D
Site 4
S41
S
S
K
Q
L
L
K
S
D
V
N
Y
Q
C
L
Site 5
T61
L
H
L
R
G
V
L
T
T
Q
P
V
E
D
E
Site 6
T62
H
L
R
G
V
L
T
T
Q
P
V
E
D
E
R
Site 7
T92
V
E
A
E
E
N
D
T
Q
I
L
F
N
Y
L
Site 8
Y98
D
T
Q
I
L
F
N
Y
L
S
S
C
K
N
E
Site 9
S100
Q
I
L
F
N
Y
L
S
S
C
K
N
E
S
E
Site 10
S101
I
L
F
N
Y
L
S
S
C
K
N
E
S
E
I
Site 11
S106
L
S
S
C
K
N
E
S
E
I
L
S
L
F
S
Site 12
S110
K
N
E
S
E
I
L
S
L
F
S
E
V
Q
G
Site 13
Y123
Q
G
P
W
S
F
I
Y
Y
Q
A
S
S
H
Y
Site 14
Y124
G
P
W
S
F
I
Y
Y
Q
A
S
S
H
Y
L
Site 15
Y130
Y
Y
Q
A
S
S
H
Y
L
W
F
G
R
D
F
Site 16
S142
R
D
F
F
G
R
R
S
L
L
W
H
F
S
N
Site 17
S158
G
K
S
F
C
L
S
S
V
G
T
Q
T
S
G
Site 18
S164
S
S
V
G
T
Q
T
S
G
L
A
N
Q
W
Q
Site 19
S176
Q
W
Q
E
V
P
A
S
G
L
F
R
I
D
L
Site 20
Y197
R
C
I
I
L
Q
L
Y
P
W
K
Y
I
S
R
Site 21
Y201
L
Q
L
Y
P
W
K
Y
I
S
R
E
N
I
I
Site 22
S214
I
I
E
E
N
V
N
S
L
S
Q
I
S
A
D
Site 23
S216
E
E
N
V
N
S
L
S
Q
I
S
A
D
L
P
Site 24
S258
A
A
L
E
T
H
C
S
N
I
S
N
V
P
P
Site 25
T308
L
P
R
D
E
N
L
T
A
N
E
V
L
K
T
Site 26
T315
T
A
N
E
V
L
K
T
C
D
R
K
A
N
V
Site 27
T366
E
E
K
T
M
P
T
T
F
N
R
E
G
N
K
Site 28
S386
E
I
P
S
E
E
F
S
K
D
V
A
A
A
A
Site 29
S402
D
S
P
N
K
H
V
S
V
P
D
R
I
T
G
Site 30
T408
V
S
V
P
D
R
I
T
G
R
A
G
L
K
E
Site 31
S420
L
K
E
L
Q
A
V
S
P
S
R
I
W
N
F
Site 32
S433
N
F
V
E
I
N
V
S
M
E
E
L
Q
K
L
Site 33
T443
E
L
Q
K
L
R
R
T
R
I
C
H
L
I
R
Site 34
S482
V
A
Q
E
G
V
K
S
Y
Q
S
N
A
K
V
Site 35
Y503
A
D
E
Q
L
A
G
Y
S
R
H
R
V
R
F
Site 36
S512
R
H
R
V
R
F
Q
S
H
G
L
E
G
L
N
Site 37
S530
M
M
E
L
G
R
I
S
S
R
N
L
G
R
D
Site 38
S531
M
E
L
G
R
I
S
S
R
N
L
G
R
D
D
Site 39
T573
I
W
E
K
A
N
L
T
L
P
R
G
I
G
E
Site 40
T594
A
A
V
E
L
G
L
T
A
S
A
L
L
P
K
Site 41
S596
V
E
L
G
L
T
A
S
A
L
L
P
K
R
A
Site 42
S608
K
R
A
M
Q
F
G
S
R
I
A
K
M
E
K
Site 43
T641
N
L
S
I
E
K
E
T
K
L
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation