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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C12orf48
Full Name:
UPF0419 protein C12orf48
Alias:
Type:
Mass (Da):
65081
Number AA:
579
UniProt ID:
Q9NWS1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
V
F
N
Q
K
S
V
S
D
M
I
K
E
Site 2
S10
V
F
N
Q
K
S
V
S
D
M
I
K
E
F
R
Site 3
T30
L
C
N
S
E
R
T
T
L
C
G
A
D
S
M
Site 4
S44
M
L
L
A
L
Q
L
S
M
A
E
N
N
K
Q
Site 5
T57
K
Q
H
S
G
E
F
T
V
S
L
S
D
V
L
Site 6
Y69
D
V
L
L
T
W
K
Y
L
L
H
E
K
L
N
Site 7
T85
P
V
E
N
M
D
V
T
D
H
Y
E
D
V
R
Site 8
Y88
N
M
D
V
T
D
H
Y
E
D
V
R
K
I
Y
Site 9
Y95
Y
E
D
V
R
K
I
Y
D
D
F
L
K
N
S
Site 10
Y124
L
T
S
N
C
E
N
Y
N
T
V
S
P
S
Q
Site 11
T126
S
N
C
E
N
Y
N
T
V
S
P
S
Q
L
L
Site 12
S128
C
E
N
Y
N
T
V
S
P
S
Q
L
L
D
F
Site 13
S137
S
Q
L
L
D
F
L
S
G
K
Q
Y
A
V
G
Site 14
Y141
D
F
L
S
G
K
Q
Y
A
V
G
D
E
T
D
Site 15
T147
Q
Y
A
V
G
D
E
T
D
L
S
I
P
T
S
Site 16
S150
V
G
D
E
T
D
L
S
I
P
T
S
P
T
S
Site 17
S154
T
D
L
S
I
P
T
S
P
T
S
K
Y
N
R
Site 18
S157
S
I
P
T
S
P
T
S
K
Y
N
R
D
N
E
Site 19
Y159
P
T
S
P
T
S
K
Y
N
R
D
N
E
K
V
Site 20
Y238
I
E
L
G
G
K
G
Y
A
P
P
P
S
D
P
Site 21
S243
K
G
Y
A
P
P
P
S
D
P
L
R
T
H
V
Site 22
T248
P
P
S
D
P
L
R
T
H
V
K
G
L
S
N
Site 23
S332
A
L
S
T
T
D
I
S
P
A
R
P
K
S
H
Site 24
S338
I
S
P
A
R
P
K
S
H
A
I
N
H
G
T
Site 25
Y347
A
I
N
H
G
T
A
Y
C
G
R
D
T
V
K
Site 26
Y377
K
N
K
A
E
L
L
Y
D
E
E
D
T
I
H
Site 27
T392
H
H
G
T
S
I
L
T
L
F
R
S
P
T
Q
Site 28
T398
L
T
L
F
R
S
P
T
Q
V
N
N
L
I
K
Site 29
T425
K
K
I
K
M
K
Q
T
L
I
R
S
Q
F
A
Site 30
Y435
R
S
Q
F
A
C
T
Y
K
D
D
Y
M
I
S
Site 31
Y439
A
C
T
Y
K
D
D
Y
M
I
S
K
D
N
W
Site 32
Y460
S
K
P
L
C
V
L
Y
M
E
N
D
L
S
E
Site 33
S466
L
Y
M
E
N
D
L
S
E
G
V
N
P
S
V
Site 34
S472
L
S
E
G
V
N
P
S
V
G
R
S
T
I
G
Site 35
S476
V
N
P
S
V
G
R
S
T
I
G
T
S
F
G
Site 36
T477
N
P
S
V
G
R
S
T
I
G
T
S
F
G
N
Site 37
S481
G
R
S
T
I
G
T
S
F
G
N
V
H
L
D
Site 38
S490
G
N
V
H
L
D
R
S
K
N
E
K
V
S
R
Site 39
S496
R
S
K
N
E
K
V
S
R
K
S
T
S
Q
T
Site 40
S499
N
E
K
V
S
R
K
S
T
S
Q
T
G
N
K
Site 41
T500
E
K
V
S
R
K
S
T
S
Q
T
G
N
K
S
Site 42
S501
K
V
S
R
K
S
T
S
Q
T
G
N
K
S
S
Site 43
T503
S
R
K
S
T
S
Q
T
G
N
K
S
S
K
R
Site 44
S507
T
S
Q
T
G
N
K
S
S
K
R
K
Q
V
D
Site 45
S508
S
Q
T
G
N
K
S
S
K
R
K
Q
V
D
L
Site 46
S540
N
A
K
I
P
K
K
S
N
D
S
Q
N
R
L
Site 47
S543
I
P
K
K
S
N
D
S
Q
N
R
L
Y
G
K
Site 48
Y548
N
D
S
Q
N
R
L
Y
G
K
L
A
K
V
A
Site 49
S557
K
L
A
K
V
A
K
S
N
K
C
T
A
K
D
Site 50
T561
V
A
K
S
N
K
C
T
A
K
D
K
L
I
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation