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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MERIT40
Full Name:
BRCA1-A complex subunit MERIT40
Alias:
Chromosome 19 open reading frame 62; CS062; FLJ20571; HSPC142; NBA1
Type:
DNA repair
Mass (Da):
36560
Number AA:
329
UniProt ID:
Q9NWV8
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070531
GO:0070552
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031572
GO:0016568
GO:0006302
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
V
A
E
P
S
S
P
T
E
E
E
E
Site 2
S8
M
E
V
A
E
P
S
S
P
T
E
E
E
E
E
Site 3
T10
V
A
E
P
S
S
P
T
E
E
E
E
E
E
E
Site 4
S20
E
E
E
E
E
E
H
S
A
E
P
R
P
R
T
Site 5
T27
S
A
E
P
R
P
R
T
R
S
N
P
E
G
A
Site 6
S29
E
P
R
P
R
T
R
S
N
P
E
G
A
E
D
Site 7
S44
R
A
V
G
A
Q
A
S
V
G
S
R
S
E
G
Site 8
S47
G
A
Q
A
S
V
G
S
R
S
E
G
E
G
E
Site 9
S49
Q
A
S
V
G
S
R
S
E
G
E
G
E
A
A
Site 10
S57
E
G
E
G
E
A
A
S
A
D
D
G
S
L
N
Site 11
S62
A
A
S
A
D
D
G
S
L
N
T
S
G
A
G
Site 12
T65
A
D
D
G
S
L
N
T
S
G
A
G
P
K
S
Site 13
S66
D
D
G
S
L
N
T
S
G
A
G
P
K
S
W
Site 14
S72
T
S
G
A
G
P
K
S
W
Q
V
P
P
P
A
Site 15
T86
A
P
E
V
Q
I
R
T
P
R
V
N
C
P
E
Site 16
S106
L
D
L
S
E
E
M
S
L
P
K
L
E
S
F
Site 17
S112
M
S
L
P
K
L
E
S
F
N
G
S
K
T
N
Site 18
S116
K
L
E
S
F
N
G
S
K
T
N
A
L
N
V
Site 19
T118
E
S
F
N
G
S
K
T
N
A
L
N
V
S
Q
Site 20
S124
K
T
N
A
L
N
V
S
Q
K
M
I
E
M
F
Site 21
S141
T
K
H
K
I
D
K
S
H
E
F
A
L
V
V
Site 22
S157
N
D
D
T
A
W
L
S
G
L
T
S
D
P
R
Site 23
S161
A
W
L
S
G
L
T
S
D
P
R
E
L
C
S
Site 24
S168
S
D
P
R
E
L
C
S
C
L
Y
D
L
E
T
Site 25
Y171
R
E
L
C
S
C
L
Y
D
L
E
T
A
S
C
Site 26
T175
S
C
L
Y
D
L
E
T
A
S
C
S
T
F
N
Site 27
S177
L
Y
D
L
E
T
A
S
C
S
T
F
N
L
E
Site 28
S188
F
N
L
E
G
L
F
S
L
I
Q
Q
K
T
E
Site 29
T194
F
S
L
I
Q
Q
K
T
E
L
P
V
T
E
N
Site 30
T199
Q
K
T
E
L
P
V
T
E
N
V
Q
T
I
P
Site 31
T229
C
Q
P
Q
F
S
L
T
E
P
M
K
K
M
F
Site 32
Y247
Y
F
F
F
D
V
V
Y
I
H
N
G
T
E
E
Site 33
S270
D
M
F
A
F
M
G
S
L
D
T
K
G
T
S
Site 34
T273
A
F
M
G
S
L
D
T
K
G
T
S
Y
K
Y
Site 35
Y280
T
K
G
T
S
Y
K
Y
E
V
A
L
A
G
P
Site 36
S309
P
L
Q
R
P
C
Q
S
H
A
S
Y
S
L
L
Site 37
Y313
P
C
Q
S
H
A
S
Y
S
L
L
E
E
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation