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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLN6
Full Name:
Ceroid-lipofuscinosis neuronal protein 6
Alias:
Type:
Mass (Da):
35919
Number AA:
311
UniProt ID:
Q9NWW5
International Prot ID:
IPI00016597
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005788
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
GO:0008203
GO:0001573
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
R
R
Q
H
L
G
A
T
G
G
P
G
A
Q
L
Site 2
S23
P
G
A
Q
L
G
A
S
F
L
Q
A
R
H
G
Site 3
S31
F
L
Q
A
R
H
G
S
V
S
A
D
E
A
A
Site 4
S33
Q
A
R
H
G
S
V
S
A
D
E
A
A
R
T
Site 5
T40
S
A
D
E
A
A
R
T
A
P
F
H
L
D
L
Site 6
T52
L
D
L
W
F
Y
F
T
L
Q
N
W
V
L
D
Site 7
S80
W
F
P
L
N
K
P
S
V
G
D
Y
F
H
M
Site 8
Y84
N
K
P
S
V
G
D
Y
F
H
M
A
Y
N
V
Site 9
S104
L
L
K
L
I
E
R
S
P
R
T
L
P
R
S
Site 10
T107
L
I
E
R
S
P
R
T
L
P
R
S
I
T
Y
Site 11
T113
R
T
L
P
R
S
I
T
Y
V
S
I
I
I
F
Site 12
Y142
H
R
L
L
F
S
G
Y
Q
H
H
L
S
V
R
Site 13
S147
S
G
Y
Q
H
H
L
S
V
R
E
N
P
I
I
Site 14
T161
I
K
N
L
K
P
E
T
L
I
D
S
F
E
L
Site 15
S165
K
P
E
T
L
I
D
S
F
E
L
L
Y
Y
Y
Site 16
Y170
I
D
S
F
E
L
L
Y
Y
Y
D
E
Y
L
G
Site 17
Y171
D
S
F
E
L
L
Y
Y
Y
D
E
Y
L
G
H
Site 18
Y172
S
F
E
L
L
Y
Y
Y
D
E
Y
L
G
H
C
Site 19
Y223
P
S
G
L
Y
Y
W
Y
L
V
T
E
G
Q
I
Site 20
S257
R
K
R
L
F
L
D
S
N
G
L
F
L
F
S
Site 21
S264
S
N
G
L
F
L
F
S
S
F
A
L
T
L
L
Site 22
Y290
D
P
V
L
R
K
K
Y
P
G
V
I
Y
V
P
Site 23
Y295
K
K
Y
P
G
V
I
Y
V
P
E
P
W
A
F
Site 24
Y303
V
P
E
P
W
A
F
Y
T
L
H
V
S
S
R
Site 25
T304
P
E
P
W
A
F
Y
T
L
H
V
S
S
R
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation