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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UCKL1
Full Name:
Uridine-cytidine kinase-like 1
Alias:
EC 2.7.1.-; EC 2.7.1.48; F538; FLJ20517; Uridine/cytidine kinase-like 1; Uridine-cytidine kinase 1-like 1; URKL1
Type:
EC 2.7.1.-; EC 2.7.1.48; Xenobiotic Metabolism - drug metabolism - other enzymes; Nucleotide Metabolism - pyrimidine; Transferase
Mass (Da):
61141
Number AA:
548
UniProt ID:
Q9NWZ5
International Prot ID:
IPI00384294
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016773
GO:0004849
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
R
A
D
A
D
P
S
P
T
S
P
P
T
A
Site 2
T15
A
D
A
D
P
S
P
T
S
P
P
T
A
R
D
Site 3
S16
D
A
D
P
S
P
T
S
P
P
T
A
R
D
T
Site 4
T19
P
S
P
T
S
P
P
T
A
R
D
T
P
G
R
Site 5
T23
S
P
P
T
A
R
D
T
P
G
R
Q
A
E
K
Site 6
S31
P
G
R
Q
A
E
K
S
E
T
A
C
E
D
R
Site 7
T33
R
Q
A
E
K
S
E
T
A
C
E
D
R
S
N
Site 8
S39
E
T
A
C
E
D
R
S
N
A
E
S
L
D
R
Site 9
S43
E
D
R
S
N
A
E
S
L
D
R
L
L
P
P
Site 10
T53
R
L
L
P
P
V
G
T
G
R
S
P
R
K
R
Site 11
S56
P
P
V
G
T
G
R
S
P
R
K
R
T
T
S
Site 12
T61
G
R
S
P
R
K
R
T
T
S
Q
C
K
S
E
Site 13
T62
R
S
P
R
K
R
T
T
S
Q
C
K
S
E
P
Site 14
S63
S
P
R
K
R
T
T
S
Q
C
K
S
E
P
P
Site 15
S67
R
T
T
S
Q
C
K
S
E
P
P
L
L
R
T
Site 16
S75
E
P
P
L
L
R
T
S
K
R
T
I
Y
T
A
Site 17
Y80
R
T
S
K
R
T
I
Y
T
A
G
R
P
P
W
Site 18
T81
T
S
K
R
T
I
Y
T
A
G
R
P
P
W
Y
Site 19
Y88
T
A
G
R
P
P
W
Y
N
E
H
G
T
Q
S
Site 20
T93
P
W
Y
N
E
H
G
T
Q
S
K
E
A
F
A
Site 21
S95
Y
N
E
H
G
T
Q
S
K
E
A
F
A
I
G
Site 22
S107
A
I
G
L
G
G
G
S
A
S
G
K
T
T
V
Site 23
S109
G
L
G
G
G
S
A
S
G
K
T
T
V
A
R
Site 24
Y136
L
L
S
M
D
S
F
Y
K
V
L
T
E
Q
Q
Site 25
S177
K
K
L
K
Q
G
K
S
V
K
V
P
I
Y
D
Site 26
Y183
K
S
V
K
V
P
I
Y
D
F
T
T
H
S
R
Site 27
T187
V
P
I
Y
D
F
T
T
H
S
R
K
K
D
W
Site 28
T196
S
R
K
K
D
W
K
T
L
Y
G
A
N
V
I
Site 29
Y198
K
K
D
W
K
T
L
Y
G
A
N
V
I
I
F
Site 30
T215
I
M
A
F
A
D
K
T
L
L
E
L
L
D
M
Site 31
S230
K
I
F
V
D
T
D
S
D
I
R
L
V
R
R
Site 32
S243
R
R
L
R
R
D
I
S
E
R
G
R
D
I
E
Site 33
Y267
V
K
P
S
F
D
Q
Y
I
Q
P
T
M
R
L
Site 34
S298
L
I
V
Q
H
V
H
S
Q
L
E
E
R
E
L
Site 35
S306
Q
L
E
E
R
E
L
S
V
R
A
A
L
A
S
Site 36
T323
Q
C
H
P
L
P
R
T
L
S
V
L
K
S
T
Site 37
S325
H
P
L
P
R
T
L
S
V
L
K
S
T
P
Q
Site 38
S329
R
T
L
S
V
L
K
S
T
P
Q
V
R
G
M
Site 39
T330
T
L
S
V
L
K
S
T
P
Q
V
R
G
M
H
Site 40
T345
T
I
I
R
D
K
E
T
S
R
D
E
F
I
F
Site 41
S346
I
I
R
D
K
E
T
S
R
D
E
F
I
F
Y
Site 42
Y353
S
R
D
E
F
I
F
Y
S
K
R
L
M
R
L
Site 43
S354
R
D
E
F
I
F
Y
S
K
R
L
M
R
L
L
Site 44
T378
F
Q
D
C
V
V
Q
T
P
Q
G
Q
D
Y
A
Site 45
Y384
Q
T
P
Q
G
Q
D
Y
A
G
K
C
Y
A
G
Site 46
S398
G
K
Q
I
T
G
V
S
I
L
R
A
G
E
T
Site 47
T405
S
I
L
R
A
G
E
T
M
E
P
A
L
R
A
Site 48
T421
C
K
D
V
R
I
G
T
I
L
I
Q
T
N
Q
Site 49
T430
L
I
Q
T
N
Q
L
T
G
E
P
E
L
H
Y
Site 50
Y437
T
G
E
P
E
L
H
Y
L
R
L
P
K
D
I
Site 51
Y529
I
G
N
F
G
D
R
Y
F
G
T
D
A
V
P
Site 52
T532
F
G
D
R
Y
F
G
T
D
A
V
P
D
G
S
Site 53
S539
T
D
A
V
P
D
G
S
D
E
E
E
V
A
Y
Site 54
T547
D
E
E
E
V
A
Y
T
G
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation