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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM120C
Full Name:
Constitutive coactivator of PPAR-gamma-like protein 2
Alias:
Protein FAM120C;Tumor antigen BJ-HCC-21
Type:
Mass (Da):
120576
Number AA:
1096
UniProt ID:
Q9NX05
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
D
L
L
K
L
A
R
T
V
S
R
Q
Q
Q
Q
Site 2
S31
L
K
L
A
R
T
V
S
R
Q
Q
Q
Q
Q
H
Site 3
S60
A
P
R
A
A
R
G
S
V
P
L
Q
P
P
L
Site 4
S76
P
A
A
L
G
A
Y
S
G
G
A
G
P
T
R
Site 5
Y130
G
S
A
L
P
R
L
Y
G
G
Y
Q
T
D
W
Site 6
Y133
L
P
R
L
Y
G
G
Y
Q
T
D
W
V
C
G
Site 7
T193
R
C
Q
A
E
R
Q
T
A
Q
L
I
V
G
H
Site 8
T206
G
H
V
G
N
K
G
T
P
P
P
R
A
W
F
Site 9
S237
F
R
V
K
V
F
Q
S
L
E
D
H
H
L
E
Site 10
S262
H
G
L
L
A
H
D
S
E
Y
A
L
Y
N
I
Site 11
Y264
L
L
A
H
D
S
E
Y
A
L
Y
N
I
P
S
Site 12
Y267
H
D
S
E
Y
A
L
Y
N
I
P
S
Y
Y
S
Site 13
S271
Y
A
L
Y
N
I
P
S
Y
Y
S
S
H
A
L
Site 14
Y272
A
L
Y
N
I
P
S
Y
Y
S
S
H
A
L
K
Site 15
Y273
L
Y
N
I
P
S
Y
Y
S
S
H
A
L
K
L
Site 16
S275
N
I
P
S
Y
Y
S
S
H
A
L
K
L
S
W
Site 17
S281
S
S
H
A
L
K
L
S
W
N
G
K
N
L
T
Site 18
S341
G
P
E
H
P
L
A
S
L
K
V
R
A
H
Q
Site 19
S366
K
A
V
S
E
Y
V
S
S
I
K
D
P
S
N
Site 20
S367
A
V
S
E
Y
V
S
S
I
K
D
P
S
N
L
Site 21
S372
V
S
S
I
K
D
P
S
N
L
D
V
V
G
K
Site 22
S385
G
K
D
V
F
K
Q
S
Q
S
R
T
E
D
K
Site 23
T389
F
K
Q
S
Q
S
R
T
E
D
K
I
E
R
F
Site 24
Y402
R
F
K
K
A
V
E
Y
Y
S
V
T
T
K
L
Site 25
S404
K
K
A
V
E
Y
Y
S
V
T
T
K
L
S
S
Site 26
S410
Y
S
V
T
T
K
L
S
S
L
P
V
G
P
S
Site 27
S417
S
S
L
P
V
G
P
S
F
L
G
F
R
N
N
Site 28
T438
L
P
R
N
Q
V
G
T
I
S
A
G
K
P
M
Site 29
S440
R
N
Q
V
G
T
I
S
A
G
K
P
M
F
S
Site 30
Y456
Q
V
P
Q
K
V
K
Y
P
P
P
F
P
V
G
Site 31
S466
P
F
P
V
G
P
N
S
S
L
L
F
S
S
H
Site 32
S471
P
N
S
S
L
L
F
S
S
H
A
L
G
E
S
Site 33
S472
N
S
S
L
L
F
S
S
H
A
L
G
E
S
H
Site 34
S478
S
S
H
A
L
G
E
S
H
A
F
S
E
D
P
Site 35
S482
L
G
E
S
H
A
F
S
E
D
P
M
L
Q
N
Site 36
S490
E
D
P
M
L
Q
N
S
P
F
A
N
W
A
V
Site 37
S498
P
F
A
N
W
A
V
S
Y
D
S
S
A
S
Q
Site 38
Y499
F
A
N
W
A
V
S
Y
D
S
S
A
S
Q
F
Site 39
S501
N
W
A
V
S
Y
D
S
S
A
S
Q
F
P
N
Site 40
S502
W
A
V
S
Y
D
S
S
A
S
Q
F
P
N
Y
Site 41
S504
V
S
Y
D
S
S
A
S
Q
F
P
N
Y
L
P
Site 42
Y509
S
A
S
Q
F
P
N
Y
L
P
S
K
A
S
P
Site 43
S512
Q
F
P
N
Y
L
P
S
K
A
S
P
P
L
G
Site 44
S515
N
Y
L
P
S
K
A
S
P
P
L
G
P
D
S
Site 45
S522
S
P
P
L
G
P
D
S
S
H
S
S
S
S
D
Site 46
S523
P
P
L
G
P
D
S
S
H
S
S
S
S
D
G
Site 47
S525
L
G
P
D
S
S
H
S
S
S
S
D
G
D
E
Site 48
S526
G
P
D
S
S
H
S
S
S
S
D
G
D
E
P
Site 49
S527
P
D
S
S
H
S
S
S
S
D
G
D
E
P
N
Site 50
S528
D
S
S
H
S
S
S
S
D
G
D
E
P
N
G
Site 51
S538
D
E
P
N
G
A
S
S
D
H
I
T
E
A
F
Site 52
T542
G
A
S
S
D
H
I
T
E
A
F
H
H
Q
P
Site 53
S560
N
P
N
R
D
R
G
S
W
A
Q
P
V
D
T
Site 54
T567
S
W
A
Q
P
V
D
T
G
V
S
E
A
S
L
Site 55
S570
Q
P
V
D
T
G
V
S
E
A
S
L
G
D
G
Site 56
S573
D
T
G
V
S
E
A
S
L
G
D
G
E
P
H
Site 57
S583
D
G
E
P
H
I
P
S
L
L
S
M
S
T
R
Site 58
S586
P
H
I
P
S
L
L
S
M
S
T
R
N
H
M
Site 59
S588
I
P
S
L
L
S
M
S
T
R
N
H
M
D
I
Site 60
T596
T
R
N
H
M
D
I
T
I
P
P
L
P
P
V
Site 61
Y621
R
H
R
R
G
L
M
Y
P
Y
I
Y
H
V
L
Site 62
Y623
R
R
G
L
M
Y
P
Y
I
Y
H
V
L
T
K
Site 63
Y625
G
L
M
Y
P
Y
I
Y
H
V
L
T
K
G
E
Site 64
S667
Y
V
Y
G
V
L
F
S
L
A
E
T
Q
R
K
Site 65
T671
V
L
F
S
L
A
E
T
Q
R
K
M
E
R
L
Site 66
Y699
I
L
K
E
W
S
A
Y
K
G
K
S
P
Q
T
Site 67
S703
W
S
A
Y
K
G
K
S
P
Q
T
P
E
L
V
Site 68
T706
Y
K
G
K
S
P
Q
T
P
E
L
V
S
A
L
Site 69
T714
P
E
L
V
S
A
L
T
F
R
E
W
T
C
P
Site 70
T719
A
L
T
F
R
E
W
T
C
P
N
L
K
K
L
Site 71
T750
L
A
C
M
K
S
D
T
P
S
M
L
N
P
A
Site 72
S752
C
M
K
S
D
T
P
S
M
L
N
P
A
N
V
Site 73
T789
L
H
R
H
E
L
D
T
F
L
A
Q
A
V
S
Site 74
S796
T
F
L
A
Q
A
V
S
T
Q
L
Y
E
P
D
Site 75
Y800
Q
A
V
S
T
Q
L
Y
E
P
D
R
L
Q
E
Site 76
S860
F
D
G
K
L
F
Q
S
K
L
I
K
A
G
R
Site 77
S871
K
A
G
R
E
R
V
S
L
V
E
L
C
D
G
Site 78
T884
D
G
Q
A
D
L
A
T
K
V
E
K
M
R
Q
Site 79
S892
K
V
E
K
M
R
Q
S
I
L
E
G
V
N
M
Site 80
S905
N
M
N
H
P
P
P
S
A
L
L
P
S
P
T
Site 81
Y922
P
P
M
V
P
S
L
Y
P
V
S
L
Y
S
R
Site 82
S933
L
Y
S
R
A
M
G
S
M
P
L
P
P
Q
G
Site 83
S971
V
V
G
Q
W
A
G
S
R
S
S
R
G
R
G
Site 84
S973
G
Q
W
A
G
S
R
S
S
R
G
R
G
S
F
Site 85
S974
Q
W
A
G
S
R
S
S
R
G
R
G
S
F
G
Site 86
S979
R
S
S
R
G
R
G
S
F
G
M
Q
V
V
S
Site 87
S986
S
F
G
M
Q
V
V
S
V
G
G
P
G
K
G
Site 88
T999
K
G
H
G
K
E
Q
T
G
R
G
S
K
G
H
Site 89
S1003
K
E
Q
T
G
R
G
S
K
G
H
K
K
G
N
Site 90
S1014
K
K
G
N
K
Q
G
S
S
D
G
V
S
K
S
Site 91
S1015
K
G
N
K
Q
G
S
S
D
G
V
S
K
S
L
Site 92
S1019
Q
G
S
S
D
G
V
S
K
S
L
E
L
H
Q
Site 93
S1021
S
S
D
G
V
S
K
S
L
E
L
H
Q
G
R
Site 94
S1029
L
E
L
H
Q
G
R
S
R
S
Q
V
N
G
N
Site 95
S1031
L
H
Q
G
R
S
R
S
Q
V
N
G
N
S
G
Site 96
S1046
A
L
I
K
E
E
K
S
D
H
R
L
P
A
P
Site 97
S1054
D
H
R
L
P
A
P
S
Q
C
A
L
S
R
D
Site 98
S1059
A
P
S
Q
C
A
L
S
R
D
S
N
E
C
N
Site 99
S1062
Q
C
A
L
S
R
D
S
N
E
C
N
N
G
N
Site 100
Y1071
E
C
N
N
G
N
R
Y
L
P
M
N
N
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation