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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDIT4
Full Name:
DNA damage-inducible transcript 4 protein
Alias:
HIF-1 responsive protein RTP801;Protein regulated in development and DNA damage response 1
Type:
Mass (Da):
25371
Number AA:
232
UniProt ID:
Q9NX09
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
P
S
L
W
D
R
F
S
S
S
S
T
S
S
S
Site 2
S10
S
L
W
D
R
F
S
S
S
S
T
S
S
S
P
Site 3
S11
L
W
D
R
F
S
S
S
S
T
S
S
S
P
S
Site 4
S12
W
D
R
F
S
S
S
S
T
S
S
S
P
S
S
Site 5
T13
D
R
F
S
S
S
S
T
S
S
S
P
S
S
L
Site 6
S14
R
F
S
S
S
S
T
S
S
S
P
S
S
L
P
Site 7
S15
F
S
S
S
S
T
S
S
S
P
S
S
L
P
R
Site 8
S16
S
S
S
S
T
S
S
S
P
S
S
L
P
R
T
Site 9
S18
S
S
T
S
S
S
P
S
S
L
P
R
T
P
T
Site 10
S19
S
T
S
S
S
P
S
S
L
P
R
T
P
T
P
Site 11
T23
S
P
S
S
L
P
R
T
P
T
P
D
R
P
P
Site 12
T25
S
S
L
P
R
T
P
T
P
D
R
P
P
R
S
Site 13
S32
T
P
D
R
P
P
R
S
A
W
G
S
A
T
R
Site 14
S36
P
P
R
S
A
W
G
S
A
T
R
E
E
G
F
Site 15
S46
R
E
E
G
F
D
R
S
T
S
L
E
S
S
D
Site 16
T47
E
E
G
F
D
R
S
T
S
L
E
S
S
D
C
Site 17
S48
E
G
F
D
R
S
T
S
L
E
S
S
D
C
E
Site 18
S52
R
S
T
S
L
E
S
S
D
C
E
S
L
D
S
Site 19
S56
L
E
S
S
D
C
E
S
L
D
S
S
N
S
G
Site 20
S59
S
D
C
E
S
L
D
S
S
N
S
G
F
G
P
Site 21
S60
D
C
E
S
L
D
S
S
N
S
G
F
G
P
E
Site 22
S62
E
S
L
D
S
S
N
S
G
F
G
P
E
E
D
Site 23
Y72
G
P
E
E
D
T
A
Y
L
D
G
V
S
L
P
Site 24
S85
L
P
D
F
E
L
L
S
D
P
E
D
E
H
L
Site 25
S111
L
A
Q
A
R
L
G
S
R
R
P
A
R
L
L
Site 26
Y136
K
E
L
L
R
L
A
Y
S
E
P
C
G
L
R
Site 27
S137
E
L
L
R
L
A
Y
S
E
P
C
G
L
R
G
Site 28
S156
V
C
V
E
Q
G
K
S
C
H
S
V
G
Q
L
Site 29
S183
T
L
V
L
R
L
D
S
R
L
W
P
K
I
Q
Site 30
S194
P
K
I
Q
G
L
F
S
S
A
N
S
P
F
L
Site 31
S195
K
I
Q
G
L
F
S
S
A
N
S
P
F
L
P
Site 32
Y222
R
V
I
K
K
K
L
Y
S
S
E
Q
L
L
I
Site 33
S223
V
I
K
K
K
L
Y
S
S
E
Q
L
L
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation