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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SOHLH2
Full Name:
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
Alias:
SOLH2; Spermatogenesis and oogenesis specific basic helix-loop-helix 2; TEB1
Type:
Mass (Da):
46941
Number AA:
425
UniProt ID:
Q9NX45
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0030528
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0048477
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
T
V
G
Y
L
A
D
T
V
Q
K
L
F
A
N
Site 2
T49
N
I
A
E
V
T
I
T
I
S
D
T
K
E
A
Site 3
T95
R
F
G
K
K
K
N
T
H
S
L
F
V
F
I
Site 4
S97
G
K
K
K
N
T
H
S
L
F
V
F
I
I
P
Site 5
T121
H
G
M
D
I
A
L
T
E
P
L
T
M
E
K
Site 6
Y135
K
M
S
N
V
V
K
Y
W
T
T
C
P
S
N
Site 7
S162
L
G
L
P
L
Q
R
S
Y
S
E
H
L
G
Y
Site 8
Y163
G
L
P
L
Q
R
S
Y
S
E
H
L
G
Y
F
Site 9
S164
L
P
L
Q
R
S
Y
S
E
H
L
G
Y
F
P
Site 10
Y169
S
Y
S
E
H
L
G
Y
F
P
T
D
L
F
A
Site 11
S178
P
T
D
L
F
A
C
S
E
S
L
R
N
G
N
Site 12
S180
D
L
F
A
C
S
E
S
L
R
N
G
N
G
L
Site 13
S192
N
G
L
E
L
N
A
S
L
S
E
F
E
K
N
Site 14
S194
L
E
L
N
A
S
L
S
E
F
E
K
N
K
K
Site 15
S203
F
E
K
N
K
K
I
S
L
L
H
S
S
K
E
Site 16
S207
K
K
I
S
L
L
H
S
S
K
E
K
L
R
R
Site 17
Y219
L
R
R
E
R
I
K
Y
C
C
E
Q
L
R
T
Site 18
T226
Y
C
C
E
Q
L
R
T
L
L
P
Y
V
K
G
Site 19
Y230
Q
L
R
T
L
L
P
Y
V
K
G
R
K
N
D
Site 20
S240
G
R
K
N
D
A
A
S
V
L
E
A
T
V
D
Site 21
Y248
V
L
E
A
T
V
D
Y
V
K
Y
I
R
E
K
Site 22
Y251
A
T
V
D
Y
V
K
Y
I
R
E
K
I
S
P
Site 23
S257
K
Y
I
R
E
K
I
S
P
A
V
M
A
Q
I
Site 24
T280
R
F
C
K
K
Q
Q
T
P
I
E
L
S
L
P
Site 25
T289
I
E
L
S
L
P
G
T
V
M
A
Q
R
E
N
Site 26
S297
V
M
A
Q
R
E
N
S
V
M
S
T
Y
S
P
Site 27
T301
R
E
N
S
V
M
S
T
Y
S
P
E
R
G
L
Site 28
Y302
E
N
S
V
M
S
T
Y
S
P
E
R
G
L
Q
Site 29
S303
N
S
V
M
S
T
Y
S
P
E
R
G
L
Q
F
Site 30
T321
T
C
W
N
G
C
S
T
P
D
A
E
S
S
L
Site 31
S327
S
T
P
D
A
E
S
S
L
D
E
A
V
R
V
Site 32
S336
D
E
A
V
R
V
P
S
S
S
A
S
E
N
A
Site 33
S337
E
A
V
R
V
P
S
S
S
A
S
E
N
A
I
Site 34
S338
A
V
R
V
P
S
S
S
A
S
E
N
A
I
G
Site 35
S340
R
V
P
S
S
S
A
S
E
N
A
I
G
D
P
Site 36
Y348
E
N
A
I
G
D
P
Y
K
T
H
I
S
S
A
Site 37
T350
A
I
G
D
P
Y
K
T
H
I
S
S
A
A
L
Site 38
S353
D
P
Y
K
T
H
I
S
S
A
A
L
S
L
N
Site 39
S354
P
Y
K
T
H
I
S
S
A
A
L
S
L
N
S
Site 40
S361
S
A
A
L
S
L
N
S
L
H
T
V
R
Y
Y
Site 41
T364
L
S
L
N
S
L
H
T
V
R
Y
Y
S
K
V
Site 42
Y367
N
S
L
H
T
V
R
Y
Y
S
K
V
T
P
S
Site 43
Y368
S
L
H
T
V
R
Y
Y
S
K
V
T
P
S
Y
Site 44
S369
L
H
T
V
R
Y
Y
S
K
V
T
P
S
Y
D
Site 45
T372
V
R
Y
Y
S
K
V
T
P
S
Y
D
A
T
A
Site 46
S374
Y
Y
S
K
V
T
P
S
Y
D
A
T
A
V
T
Site 47
Y375
Y
S
K
V
T
P
S
Y
D
A
T
A
V
T
N
Site 48
T378
V
T
P
S
Y
D
A
T
A
V
T
N
Q
N
I
Site 49
S391
N
I
S
I
H
L
P
S
A
M
P
P
V
S
K
Site 50
S397
P
S
A
M
P
P
V
S
K
L
L
P
R
H
C
Site 51
T405
K
L
L
P
R
H
C
T
S
G
L
G
Q
T
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation