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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LYAR
Full Name:
Cell growth-regulating nucleolar protein
Alias:
likely ortholog of mouse Ly1 antibody reactive clone; Ly1 antibody reactive; ZLYAR
Type:
Unknown function
Mass (Da):
43615
Number AA:
379
UniProt ID:
Q9NX58
International Prot ID:
IPI00015838
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y45
K
D
F
W
G
D
D
Y
K
N
H
V
K
C
I
Site 2
Y58
C
I
S
E
D
Q
K
Y
G
G
K
G
Y
E
G
Site 3
S91
L
I
K
R
P
N
V
S
P
K
V
R
E
L
L
Site 4
S102
R
E
L
L
E
Q
I
S
A
F
D
N
V
P
R
Site 5
S128
S
L
K
V
H
N
E
S
I
L
D
Q
V
W
N
Site 6
S138
D
Q
V
W
N
I
F
S
E
A
S
N
S
E
P
Site 7
S143
I
F
S
E
A
S
N
S
E
P
V
N
K
E
Q
Site 8
S166
A
N
P
H
A
E
I
S
T
K
V
P
A
S
K
Site 9
S172
I
S
T
K
V
P
A
S
K
V
K
D
A
V
E
Site 10
S215
L
E
N
H
Q
E
N
S
R
N
Q
K
P
K
K
Site 11
S244
E
V
P
E
A
N
G
S
A
G
K
R
S
K
K
Site 12
S249
N
G
S
A
G
K
R
S
K
K
K
K
Q
R
K
Site 13
S258
K
K
K
Q
R
K
D
S
A
S
E
E
E
A
H
Site 14
S260
K
Q
R
K
D
S
A
S
E
E
E
A
H
V
G
Site 15
S276
G
K
R
K
R
R
H
S
E
V
E
T
D
S
K
Site 16
T280
R
R
H
S
E
V
E
T
D
S
K
K
K
K
M
Site 17
S282
H
S
E
V
E
T
D
S
K
K
K
K
M
K
L
Site 18
T314
G
K
F
N
W
K
G
T
I
K
A
I
L
K
Q
Site 19
Y340
R
K
K
V
L
A
Q
Y
Y
T
V
T
D
E
H
Site 20
Y341
K
K
V
L
A
Q
Y
Y
T
V
T
D
E
H
H
Site 21
T342
K
V
L
A
Q
Y
Y
T
V
T
D
E
H
H
R
Site 22
S350
V
T
D
E
H
H
R
S
E
E
E
L
L
V
I
Site 23
T367
K
K
I
S
K
N
P
T
F
K
L
L
K
D
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation