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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF434
Full Name:
Zinc finger protein 434
Alias:
Human cervical cancer suppressor gene 5 protein
Type:
Mass (Da):
54929
Number AA:
485
UniProt ID:
Q9NX65
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
G
P
A
Q
R
A
L
Y
R
G
A
T
Q
R
K
Site 2
T29
R
A
L
Y
R
G
A
T
Q
R
K
D
S
H
V
Site 3
S34
G
A
T
Q
R
K
D
S
H
V
S
L
A
T
G
Site 4
S37
Q
R
K
D
S
H
V
S
L
A
T
G
V
P
W
Site 5
Y46
A
T
G
V
P
W
G
Y
E
E
T
K
T
L
L
Site 6
T51
W
G
Y
E
E
T
K
T
L
L
A
I
L
S
S
Site 7
T90
W
E
Q
G
F
L
R
T
P
E
Q
C
R
T
K
Site 8
T96
R
T
P
E
Q
C
R
T
K
F
K
S
L
Q
L
Site 9
S100
Q
C
R
T
K
F
K
S
L
Q
L
S
Y
R
K
Site 10
S104
K
F
K
S
L
Q
L
S
Y
R
K
V
R
R
G
Site 11
S127
Y
E
E
M
N
A
L
S
G
S
W
A
S
A
P
Site 12
S129
E
M
N
A
L
S
G
S
W
A
S
A
P
P
M
Site 13
S132
A
L
S
G
S
W
A
S
A
P
P
M
A
S
D
Site 14
S138
A
S
A
P
P
M
A
S
D
A
V
P
G
Q
E
Site 15
T168
P
T
E
V
E
D
G
T
V
D
G
A
D
R
D
Site 16
S217
E
N
L
K
W
D
D
S
E
E
V
E
I
N
K
Site 17
S230
N
K
A
L
Q
R
K
S
R
G
V
Y
W
H
S
Site 18
Y234
Q
R
K
S
R
G
V
Y
W
H
S
E
L
Q
K
Site 19
S245
E
L
Q
K
G
L
E
S
E
P
T
S
R
R
Q
Site 20
T248
K
G
L
E
S
E
P
T
S
R
R
Q
C
R
N
Site 21
S249
G
L
E
S
E
P
T
S
R
R
Q
C
R
N
S
Site 22
S256
S
R
R
Q
C
R
N
S
P
G
E
S
E
E
K
Site 23
S260
C
R
N
S
P
G
E
S
E
E
K
T
P
S
Q
Site 24
T264
P
G
E
S
E
E
K
T
P
S
Q
E
K
M
S
Site 25
S266
E
S
E
E
K
T
P
S
Q
E
K
M
S
H
Q
Site 26
S274
Q
E
K
M
S
H
Q
S
F
C
A
R
D
K
A
Site 27
S292
I
L
C
G
K
N
C
S
Q
S
V
H
S
P
H
Site 28
S294
C
G
K
N
C
S
Q
S
V
H
S
P
H
K
P
Site 29
S297
N
C
S
Q
S
V
H
S
P
H
K
P
A
L
K
Site 30
S309
A
L
K
L
E
K
V
S
Q
C
P
E
C
G
K
Site 31
T317
Q
C
P
E
C
G
K
T
F
S
R
S
S
Y
L
Site 32
S319
P
E
C
G
K
T
F
S
R
S
S
Y
L
V
R
Site 33
S321
C
G
K
T
F
S
R
S
S
Y
L
V
R
H
Q
Site 34
S322
G
K
T
F
S
R
S
S
Y
L
V
R
H
Q
R
Site 35
Y323
K
T
F
S
R
S
S
Y
L
V
R
H
Q
R
I
Site 36
T332
V
R
H
Q
R
I
H
T
G
E
K
P
H
K
C
Site 37
S340
G
E
K
P
H
K
C
S
E
C
G
K
G
F
S
Site 38
S347
S
E
C
G
K
G
F
S
E
R
S
N
L
T
A
Site 39
T360
T
A
H
L
R
T
H
T
G
E
R
P
Y
Q
C
Site 40
Y365
T
H
T
G
E
R
P
Y
Q
C
G
Q
C
G
K
Site 41
S373
Q
C
G
Q
C
G
K
S
F
N
Q
S
S
S
L
Site 42
S377
C
G
K
S
F
N
Q
S
S
S
L
I
V
H
Q
Site 43
S379
K
S
F
N
Q
S
S
S
L
I
V
H
Q
R
T
Site 44
T386
S
L
I
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 45
T388
I
V
H
Q
R
T
H
T
G
E
K
P
Y
Q
C
Site 46
Y393
T
H
T
G
E
K
P
Y
Q
C
I
V
C
G
K
Site 47
S405
C
G
K
R
F
N
N
S
S
Q
F
S
A
H
R
Site 48
S406
G
K
R
F
N
N
S
S
Q
F
S
A
H
R
R
Site 49
S409
F
N
N
S
S
Q
F
S
A
H
R
R
I
H
T
Site 50
T416
S
A
H
R
R
I
H
T
G
E
S
P
Y
K
C
Site 51
S419
R
R
I
H
T
G
E
S
P
Y
K
C
A
V
C
Site 52
S434
G
K
I
F
N
N
S
S
H
F
S
A
H
R
K
Site 53
S437
F
N
N
S
S
H
F
S
A
H
R
K
T
H
T
Site 54
T442
H
F
S
A
H
R
K
T
H
T
G
E
K
P
Y
Site 55
T459
S
H
C
E
R
G
F
T
K
N
S
A
L
T
R
Site 56
S462
E
R
G
F
T
K
N
S
A
L
T
R
H
Q
T
Site 57
T469
S
A
L
T
R
H
Q
T
V
H
M
K
A
V
L
Site 58
S478
H
M
K
A
V
L
S
S
Q
E
G
R
D
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation