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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MCM9
Full Name:
DNA replication licensing factor MCM9
Alias:
C6orf61; DJ329L24.3; FLJ20170; MCMDC1; MGC35304; Minichromosome maintenance complex component 9; Mini-chromosome maintenance deficient 9; Mini-chromosome maintenance deficient domain-containing 1
Type:
Mass (Da):
127338
Number AA:
1143
UniProt ID:
Q9NXL9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003677
GO:0017111
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
V
G
Q
V
F
E
S
Y
V
S
E
Y
H
K
N
Site 2
Y20
F
E
S
Y
V
S
E
Y
H
K
N
D
I
L
L
Site 3
Y38
E
R
D
E
D
A
H
Y
P
V
V
V
N
A
M
Site 4
Y57
T
N
M
E
I
G
E
Y
F
N
M
F
P
S
E
Site 5
T67
M
F
P
S
E
V
L
T
I
F
D
S
A
L
R
Site 6
S85
L
T
I
L
Q
S
L
S
Q
P
E
A
V
S
M
Site 7
S101
Q
N
L
H
A
R
I
S
G
L
P
V
C
P
E
Site 8
T117
V
R
E
H
I
P
K
T
K
D
V
G
H
F
L
Site 9
S134
T
G
T
V
I
R
T
S
L
V
K
V
L
E
F
Site 10
Y145
V
L
E
F
E
R
D
Y
M
C
N
K
C
K
H
Site 11
Y164
K
A
D
F
E
Q
Y
Y
T
F
C
R
P
S
S
Site 12
T165
A
D
F
E
Q
Y
Y
T
F
C
R
P
S
S
C
Site 13
S170
Y
Y
T
F
C
R
P
S
S
C
P
S
L
E
S
Site 14
S171
Y
T
F
C
R
P
S
S
C
P
S
L
E
S
C
Site 15
S174
C
R
P
S
S
C
P
S
L
E
S
C
D
S
S
Site 16
S177
S
S
C
P
S
L
E
S
C
D
S
S
K
F
T
Site 17
S180
P
S
L
E
S
C
D
S
S
K
F
T
C
L
S
Site 18
S181
S
L
E
S
C
D
S
S
K
F
T
C
L
S
G
Site 19
T184
S
C
D
S
S
K
F
T
C
L
S
G
L
S
S
Site 20
S187
S
S
K
F
T
C
L
S
G
L
S
S
S
P
T
Site 21
S190
F
T
C
L
S
G
L
S
S
S
P
T
R
C
R
Site 22
S191
T
C
L
S
G
L
S
S
S
P
T
R
C
R
D
Site 23
S192
C
L
S
G
L
S
S
S
P
T
R
C
R
D
Y
Site 24
T194
S
G
L
S
S
S
P
T
R
C
R
D
Y
Q
E
Site 25
Y199
S
P
T
R
C
R
D
Y
Q
E
I
K
I
Q
E
Site 26
S212
Q
E
Q
V
Q
R
L
S
V
G
S
I
P
R
S
Site 27
S215
V
Q
R
L
S
V
G
S
I
P
R
S
M
K
V
Site 28
S231
L
E
D
D
L
V
D
S
C
K
S
G
D
D
L
Site 29
S234
D
L
V
D
S
C
K
S
G
D
D
L
T
I
Y
Site 30
Y241
S
G
D
D
L
T
I
Y
G
I
V
M
Q
R
W
Site 31
Y294
E
F
E
D
F
W
E
Y
Y
K
S
D
P
F
A
Site 32
Y295
F
E
D
F
W
E
Y
Y
K
S
D
P
F
A
G
Site 33
S346
G
T
R
V
R
G
E
S
H
L
L
L
V
G
D
Site 34
T356
L
L
V
G
D
P
G
T
G
K
S
Q
F
L
K
Site 35
S359
G
D
P
G
T
G
K
S
Q
F
L
K
Y
A
A
Site 36
Y364
G
K
S
Q
F
L
K
Y
A
A
K
I
T
P
R
Site 37
T376
T
P
R
S
V
L
T
T
G
I
G
S
T
S
A
Site 38
T425
S
L
K
E
H
D
R
T
S
I
H
E
A
M
E
Site 39
S426
L
K
E
H
D
R
T
S
I
H
E
A
M
E
Q
Site 40
T452
C
K
L
N
T
R
T
T
I
L
A
A
T
N
P
Site 41
T492
L
I
L
V
L
L
D
T
K
N
E
D
W
D
R
Site 42
S502
E
D
W
D
R
I
I
S
S
F
I
L
E
N
K
Site 43
S503
D
W
D
R
I
I
S
S
F
I
L
E
N
K
G
Site 44
Y511
F
I
L
E
N
K
G
Y
P
S
K
S
E
K
L
Site 45
S513
L
E
N
K
G
Y
P
S
K
S
E
K
L
W
S
Site 46
S515
N
K
G
Y
P
S
K
S
E
K
L
W
S
M
E
Site 47
S520
S
K
S
E
K
L
W
S
M
E
K
M
K
T
Y
Site 48
Y527
S
M
E
K
M
K
T
Y
F
C
L
I
R
N
L
Site 49
T537
L
I
R
N
L
Q
P
T
L
S
D
V
G
N
Q
Site 50
S539
R
N
L
Q
P
T
L
S
D
V
G
N
Q
V
L
Site 51
Y550
N
Q
V
L
L
R
Y
Y
Q
M
Q
R
Q
S
D
Site 52
T564
D
C
R
N
A
A
R
T
T
I
R
L
L
E
S
Site 53
T565
C
R
N
A
A
R
T
T
I
R
L
L
E
S
L
Site 54
T618
G
G
V
N
A
L
H
T
S
F
P
E
N
P
G
Site 55
S619
G
V
N
A
L
H
T
S
F
P
E
N
P
G
E
Site 56
Y628
P
E
N
P
G
E
Q
Y
Q
R
Q
C
E
L
I
Site 57
S659
L
E
R
L
Q
N
Q
S
V
H
Q
S
Q
P
R
Site 58
S663
Q
N
Q
S
V
H
Q
S
Q
P
R
V
L
E
V
Site 59
T672
P
R
V
L
E
V
E
T
T
P
G
S
L
R
N
Site 60
T673
R
V
L
E
V
E
T
T
P
G
S
L
R
N
G
Site 61
S676
E
V
E
T
T
P
G
S
L
R
N
G
P
G
E
Site 62
S685
R
N
G
P
G
E
E
S
N
F
R
T
S
S
Q
Site 63
T689
G
E
E
S
N
F
R
T
S
S
Q
Q
E
I
N
Site 64
S690
E
E
S
N
F
R
T
S
S
Q
Q
E
I
N
Y
Site 65
S691
E
S
N
F
R
T
S
S
Q
Q
E
I
N
Y
S
Site 66
Y697
S
S
Q
Q
E
I
N
Y
S
T
H
I
F
S
P
Site 67
S698
S
Q
Q
E
I
N
Y
S
T
H
I
F
S
P
G
Site 68
T699
Q
Q
E
I
N
Y
S
T
H
I
F
S
P
G
G
Site 69
S703
N
Y
S
T
H
I
F
S
P
G
G
S
P
E
G
Site 70
S707
H
I
F
S
P
G
G
S
P
E
G
S
P
V
L
Site 71
S711
P
G
G
S
P
E
G
S
P
V
L
D
P
P
P
Site 72
S725
P
H
L
E
P
N
R
S
T
S
R
K
H
S
A
Site 73
T726
H
L
E
P
N
R
S
T
S
R
K
H
S
A
Q
Site 74
S727
L
E
P
N
R
S
T
S
R
K
H
S
A
Q
H
Site 75
S731
R
S
T
S
R
K
H
S
A
Q
H
K
N
N
R
Site 76
S753
D
F
M
A
T
H
Q
S
E
P
K
N
T
V
V
Site 77
T758
H
Q
S
E
P
K
N
T
V
V
V
S
P
H
P
Site 78
S762
P
K
N
T
V
V
V
S
P
H
P
K
T
S
G
Site 79
S768
V
S
P
H
P
K
T
S
G
E
N
M
A
S
K
Site 80
S774
T
S
G
E
N
M
A
S
K
I
S
N
S
T
S
Site 81
S777
E
N
M
A
S
K
I
S
N
S
T
S
Q
G
K
Site 82
S779
M
A
S
K
I
S
N
S
T
S
Q
G
K
E
K
Site 83
S781
S
K
I
S
N
S
T
S
Q
G
K
E
K
S
E
Site 84
S787
T
S
Q
G
K
E
K
S
E
P
G
Q
R
S
K
Site 85
T806
L
L
P
S
P
G
E
T
G
V
P
W
R
A
D
Site 86
S827
K
K
R
L
A
L
D
S
E
A
A
V
S
A
D
Site 87
S832
L
D
S
E
A
A
V
S
A
D
K
P
D
S
V
Site 88
S838
V
S
A
D
K
P
D
S
V
L
T
H
H
V
P
Site 89
S863
A
Q
K
L
C
R
N
S
T
R
V
P
A
Q
C
Site 90
T864
Q
K
L
C
R
N
S
T
R
V
P
A
Q
C
T
Site 91
T871
T
R
V
P
A
Q
C
T
V
P
S
H
P
Q
S
Site 92
S874
P
A
Q
C
T
V
P
S
H
P
Q
S
T
P
V
Site 93
S878
T
V
P
S
H
P
Q
S
T
P
V
H
S
P
D
Site 94
T879
V
P
S
H
P
Q
S
T
P
V
H
S
P
D
R
Site 95
S883
P
Q
S
T
P
V
H
S
P
D
R
R
L
D
S
Site 96
S890
S
P
D
R
R
L
D
S
P
K
R
K
R
P
K
Site 97
S898
P
K
R
K
R
P
K
S
L
A
Q
V
E
E
P
Site 98
S915
E
N
V
K
P
P
G
S
P
V
A
K
L
A
K
Site 99
T924
V
A
K
L
A
K
F
T
F
K
Q
K
S
K
L
Site 100
S929
K
F
T
F
K
Q
K
S
K
L
I
H
S
F
E
Site 101
S934
Q
K
S
K
L
I
H
S
F
E
D
H
S
H
V
Site 102
S939
I
H
S
F
E
D
H
S
H
V
S
P
G
A
T
Site 103
S942
F
E
D
H
S
H
V
S
P
G
A
T
K
I
A
Site 104
T946
S
H
V
S
P
G
A
T
K
I
A
V
H
S
P
Site 105
S952
A
T
K
I
A
V
H
S
P
K
I
S
Q
R
R
Site 106
S956
A
V
H
S
P
K
I
S
Q
R
R
T
R
R
D
Site 107
T960
P
K
I
S
Q
R
R
T
R
R
D
A
A
L
P
Site 108
T975
V
K
R
P
G
K
L
T
S
T
P
G
N
Q
I
Site 109
S976
K
R
P
G
K
L
T
S
T
P
G
N
Q
I
S
Site 110
T977
R
P
G
K
L
T
S
T
P
G
N
Q
I
S
S
Site 111
S983
S
T
P
G
N
Q
I
S
S
Q
P
Q
G
E
T
Site 112
S984
T
P
G
N
Q
I
S
S
Q
P
Q
G
E
T
K
Site 113
S994
Q
G
E
T
K
E
V
S
Q
Q
P
P
E
K
H
Site 114
S1042
G
D
K
K
E
E
V
S
G
S
N
K
S
G
K
Site 115
S1044
K
K
E
E
V
S
G
S
N
K
S
G
K
V
H
Site 116
S1047
E
V
S
G
S
N
K
S
G
K
V
H
A
C
T
Site 117
T1064
R
L
A
N
F
C
F
T
P
P
S
E
S
K
S
Site 118
S1067
N
F
C
F
T
P
P
S
E
S
K
S
K
S
P
Site 119
S1069
C
F
T
P
P
S
E
S
K
S
K
S
P
P
P
Site 120
S1071
T
P
P
S
E
S
K
S
K
S
P
P
P
E
R
Site 121
S1073
P
S
E
S
K
S
K
S
P
P
P
E
R
K
N
Site 122
S1087
N
R
G
E
R
G
P
S
S
P
P
T
T
T
A
Site 123
S1088
R
G
E
R
G
P
S
S
P
P
T
T
T
A
P
Site 124
T1091
R
G
P
S
S
P
P
T
T
T
A
P
M
R
V
Site 125
T1092
G
P
S
S
P
P
T
T
T
A
P
M
R
V
S
Site 126
S1099
T
T
A
P
M
R
V
S
K
R
K
S
F
Q
L
Site 127
S1103
M
R
V
S
K
R
K
S
F
Q
L
R
G
S
T
Site 128
S1109
K
S
F
Q
L
R
G
S
T
E
K
L
I
V
S
Site 129
T1110
S
F
Q
L
R
G
S
T
E
K
L
I
V
S
K
Site 130
T1122
V
S
K
E
S
L
F
T
L
P
E
L
G
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation