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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ING3
Full Name:
Inhibitor of growth protein 3
Alias:
p47ING3 protein
Type:
Mass (Da):
46725
Number AA:
418
UniProt ID:
Q9NXR8
International Prot ID:
IPI00387159
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0001558
GO:0006139
GO:0006325
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
M
D
L
R
D
R
F
T
E
M
R
E
M
D
L
Site 2
S44
D
Q
L
E
Q
R
V
S
E
F
F
M
N
A
K
Site 3
Y69
M
A
S
I
K
K
D
Y
Y
K
A
L
E
D
A
Site 4
Y70
A
S
I
K
K
D
Y
Y
K
A
L
E
D
A
D
Site 5
Y87
V
Q
L
A
N
Q
I
Y
D
L
V
D
R
H
L
Site 6
S123
T
E
I
L
E
R
R
S
L
E
L
D
T
P
S
Site 7
T128
R
R
S
L
E
L
D
T
P
S
Q
P
V
N
N
Site 8
S130
S
L
E
L
D
T
P
S
Q
P
V
N
N
H
H
Site 9
S140
V
N
N
H
H
A
H
S
H
T
P
V
E
K
R
Site 10
T142
N
H
H
A
H
S
H
T
P
V
E
K
R
K
Y
Site 11
Y149
T
P
V
E
K
R
K
Y
N
P
T
S
H
H
T
Site 12
T152
E
K
R
K
Y
N
P
T
S
H
H
T
T
T
D
Site 13
T157
N
P
T
S
H
H
T
T
T
D
H
I
P
E
K
Site 14
S168
I
P
E
K
K
F
K
S
E
A
L
L
S
T
L
Site 15
S173
F
K
S
E
A
L
L
S
T
L
T
S
D
A
S
Site 16
T176
E
A
L
L
S
T
L
T
S
D
A
S
K
E
N
Site 17
S177
A
L
L
S
T
L
T
S
D
A
S
K
E
N
T
Site 18
S180
S
T
L
T
S
D
A
S
K
E
N
T
L
G
C
Site 19
T184
S
D
A
S
K
E
N
T
L
G
C
R
N
N
N
Site 20
S192
L
G
C
R
N
N
N
S
T
A
S
S
N
N
A
Site 21
T193
G
C
R
N
N
N
S
T
A
S
S
N
N
A
Y
Site 22
S196
N
N
N
S
T
A
S
S
N
N
A
Y
N
V
N
Site 23
Y200
T
A
S
S
N
N
A
Y
N
V
N
S
S
Q
P
Site 24
S204
N
N
A
Y
N
V
N
S
S
Q
P
L
G
S
Y
Site 25
S205
N
A
Y
N
V
N
S
S
Q
P
L
G
S
Y
N
Site 26
S210
N
S
S
Q
P
L
G
S
Y
N
I
G
S
L
S
Site 27
Y211
S
S
Q
P
L
G
S
Y
N
I
G
S
L
S
S
Site 28
S215
L
G
S
Y
N
I
G
S
L
S
S
G
T
G
A
Site 29
S217
S
Y
N
I
G
S
L
S
S
G
T
G
A
G
A
Site 30
T245
Q
M
K
E
G
R
R
T
S
S
L
K
A
S
Y
Site 31
S246
M
K
E
G
R
R
T
S
S
L
K
A
S
Y
E
Site 32
S247
K
E
G
R
R
T
S
S
L
K
A
S
Y
E
A
Site 33
S251
R
T
S
S
L
K
A
S
Y
E
A
F
K
N
N
Site 34
S267
F
Q
L
G
K
E
F
S
M
A
R
E
T
V
G
Site 35
T272
E
F
S
M
A
R
E
T
V
G
Y
S
S
S
S
Site 36
Y275
M
A
R
E
T
V
G
Y
S
S
S
S
A
L
M
Site 37
S276
A
R
E
T
V
G
Y
S
S
S
S
A
L
M
T
Site 38
T283
S
S
S
S
A
L
M
T
T
L
T
Q
N
A
S
Site 39
T284
S
S
S
A
L
M
T
T
L
T
Q
N
A
S
S
Site 40
T286
S
A
L
M
T
T
L
T
Q
N
A
S
S
S
A
Site 41
S290
T
T
L
T
Q
N
A
S
S
S
A
A
D
S
R
Site 42
S292
L
T
Q
N
A
S
S
S
A
A
D
S
R
S
G
Site 43
S296
A
S
S
S
A
A
D
S
R
S
G
R
K
S
K
Site 44
S298
S
S
A
A
D
S
R
S
G
R
K
S
K
N
N
Site 45
S302
D
S
R
S
G
R
K
S
K
N
N
N
K
S
S
Site 46
S308
K
S
K
N
N
N
K
S
S
S
Q
Q
S
S
S
Site 47
S309
S
K
N
N
N
K
S
S
S
Q
Q
S
S
S
S
Site 48
S310
K
N
N
N
K
S
S
S
Q
Q
S
S
S
S
S
Site 49
S313
N
K
S
S
S
Q
Q
S
S
S
S
S
S
S
S
Site 50
S314
K
S
S
S
Q
Q
S
S
S
S
S
S
S
S
S
Site 51
S315
S
S
S
Q
Q
S
S
S
S
S
S
S
S
S
L
Site 52
S316
S
S
Q
Q
S
S
S
S
S
S
S
S
S
L
S
Site 53
S317
S
Q
Q
S
S
S
S
S
S
S
S
S
L
S
S
Site 54
S318
Q
Q
S
S
S
S
S
S
S
S
S
L
S
S
C
Site 55
S319
Q
S
S
S
S
S
S
S
S
S
L
S
S
C
S
Site 56
S320
S
S
S
S
S
S
S
S
S
L
S
S
C
S
S
Site 57
S321
S
S
S
S
S
S
S
S
L
S
S
C
S
S
S
Site 58
S323
S
S
S
S
S
S
L
S
S
C
S
S
S
S
T
Site 59
S324
S
S
S
S
S
L
S
S
C
S
S
S
S
T
V
Site 60
S326
S
S
S
L
S
S
C
S
S
S
S
T
V
V
Q
Site 61
S327
S
S
L
S
S
C
S
S
S
S
T
V
V
Q
E
Site 62
S328
S
L
S
S
C
S
S
S
S
T
V
V
Q
E
I
Site 63
S329
L
S
S
C
S
S
S
S
T
V
V
Q
E
I
S
Site 64
T330
S
S
C
S
S
S
S
T
V
V
Q
E
I
S
Q
Site 65
S336
S
T
V
V
Q
E
I
S
Q
Q
T
T
V
V
P
Site 66
T340
Q
E
I
S
Q
Q
T
T
V
V
P
E
S
D
S
Site 67
S345
Q
T
T
V
V
P
E
S
D
S
N
S
Q
V
D
Site 68
S347
T
V
V
P
E
S
D
S
N
S
Q
V
D
W
T
Site 69
S349
V
P
E
S
D
S
N
S
Q
V
D
W
T
Y
D
Site 70
T354
S
N
S
Q
V
D
W
T
Y
D
P
N
E
P
R
Site 71
Y355
N
S
Q
V
D
W
T
Y
D
P
N
E
P
R
Y
Site 72
Y362
Y
D
P
N
E
P
R
Y
C
I
C
N
Q
V
S
Site 73
Y402
E
A
P
K
G
K
W
Y
C
P
Q
C
T
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation