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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF586
Full Name:
Zinc finger protein 586
Alias:
Type:
Mass (Da):
46413
Number AA:
402
UniProt ID:
Q9NXT0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
L
R
A
P
A
Q
S
S
V
T
F
E
D
V
Site 2
S14
L
R
A
P
A
Q
S
S
V
T
F
E
D
V
A
Site 3
Y40
N
E
A
Q
R
C
L
Y
R
D
V
M
L
E
T
Site 4
S67
G
E
D
E
A
A
P
S
K
Q
S
T
C
I
H
Site 5
T71
A
A
P
S
K
Q
S
T
C
I
H
I
Y
K
D
Site 6
Y76
Q
S
T
C
I
H
I
Y
K
D
Q
G
G
H
S
Site 7
S83
Y
K
D
Q
G
G
H
S
G
E
R
P
Y
E
C
Site 8
Y88
G
H
S
G
E
R
P
Y
E
C
G
E
Y
R
K
Site 9
Y93
R
P
Y
E
C
G
E
Y
R
K
L
F
K
N
K
Site 10
S101
R
K
L
F
K
N
K
S
C
L
T
E
P
R
R
Site 11
T104
F
K
N
K
S
C
L
T
E
P
R
R
D
H
K
Site 12
Y122
V
R
T
G
E
R
P
Y
E
C
S
K
Y
G
K
Site 13
Y127
R
P
Y
E
C
S
K
Y
G
K
L
F
H
Q
K
Site 14
T145
H
I
H
E
R
F
H
T
G
Q
K
T
Y
E
C
Site 15
T149
R
F
H
T
G
Q
K
T
Y
E
C
S
E
C
G
Site 16
Y150
F
H
T
G
Q
K
T
Y
E
C
S
E
C
G
K
Site 17
S158
E
C
S
E
C
G
K
S
F
H
Q
S
S
S
L
Site 18
S162
C
G
K
S
F
H
Q
S
S
S
L
L
Q
R
Q
Site 19
S164
K
S
F
H
Q
S
S
S
L
L
Q
R
Q
T
L
Site 20
T170
S
S
L
L
Q
R
Q
T
L
H
T
R
E
R
P
Site 21
T173
L
Q
R
Q
T
L
H
T
R
E
R
P
Y
E
C
Site 22
Y178
L
H
T
R
E
R
P
Y
E
C
I
E
C
G
K
Site 23
S191
G
K
A
F
A
E
K
S
S
L
I
N
H
R
K
Site 24
Y206
V
H
S
G
A
K
R
Y
E
C
N
E
C
G
K
Site 25
S214
E
C
N
E
C
G
K
S
F
A
Y
T
S
S
L
Site 26
Y217
E
C
G
K
S
F
A
Y
T
S
S
L
I
K
H
Site 27
T218
C
G
K
S
F
A
Y
T
S
S
L
I
K
H
R
Site 28
S219
G
K
S
F
A
Y
T
S
S
L
I
K
H
R
R
Site 29
S220
K
S
F
A
Y
T
S
S
L
I
K
H
R
R
I
Site 30
T229
I
K
H
R
R
I
H
T
G
E
R
P
Y
E
C
Site 31
Y234
I
H
T
G
E
R
P
Y
E
C
S
E
C
G
R
Site 32
S237
G
E
R
P
Y
E
C
S
E
C
G
R
S
F
A
Site 33
S242
E
C
S
E
C
G
R
S
F
A
E
N
S
S
L
Site 34
S248
R
S
F
A
E
N
S
S
L
I
K
H
L
R
V
Site 35
T257
I
K
H
L
R
V
H
T
G
E
R
P
Y
E
C
Site 36
Y262
V
H
T
G
E
R
P
Y
E
C
V
E
C
G
K
Site 37
S270
E
C
V
E
C
G
K
S
F
R
R
S
S
S
L
Site 38
S274
C
G
K
S
F
R
R
S
S
S
L
L
Q
H
Q
Site 39
S275
G
K
S
F
R
R
S
S
S
L
L
Q
H
Q
R
Site 40
S276
K
S
F
R
R
S
S
S
L
L
Q
H
Q
R
V
Site 41
T285
L
Q
H
Q
R
V
H
T
R
E
R
P
Y
E
C
Site 42
Y290
V
H
T
R
E
R
P
Y
E
C
S
E
C
G
K
Site 43
S293
R
E
R
P
Y
E
C
S
E
C
G
K
S
F
S
Site 44
S298
E
C
S
E
C
G
K
S
F
S
L
R
S
N
L
Site 45
S300
S
E
C
G
K
S
F
S
L
R
S
N
L
I
H
Site 46
T313
I
H
H
Q
R
V
H
T
G
E
R
H
E
C
G
Site 47
S325
E
C
G
Q
C
G
K
S
F
S
R
K
S
S
L
Site 48
S327
G
Q
C
G
K
S
F
S
R
K
S
S
L
I
I
Site 49
S330
G
K
S
F
S
R
K
S
S
L
I
I
H
L
R
Site 50
S331
K
S
F
S
R
K
S
S
L
I
I
H
L
R
V
Site 51
T340
I
I
H
L
R
V
H
T
G
E
R
P
Y
E
C
Site 52
Y345
V
H
T
G
E
R
P
Y
E
C
S
D
C
G
K
Site 53
S348
G
E
R
P
Y
E
C
S
D
C
G
K
S
F
A
Site 54
S353
E
C
S
D
C
G
K
S
F
A
E
N
S
S
L
Site 55
S359
K
S
F
A
E
N
S
S
L
I
K
H
L
R
V
Site 56
Y373
V
H
T
G
E
R
P
Y
E
C
I
D
C
G
K
Site 57
S381
E
C
I
D
C
G
K
S
F
R
H
S
S
S
F
Site 58
S385
C
G
K
S
F
R
H
S
S
S
F
R
R
H
Q
Site 59
S386
G
K
S
F
R
H
S
S
S
F
R
R
H
Q
R
Site 60
S387
K
S
F
R
H
S
S
S
F
R
R
H
Q
R
V
Site 61
T396
R
R
H
Q
R
V
H
T
G
M
R
P
Y
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation