KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CDKN2AIP
Full Name:
CDKN2A-interacting protein
Alias:
CDKN2A interacting protein; Collaborates/cooperates with ARF (alternate reading frame); Collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF; DKFZp686M0665; FLJ20036
Type:
Unknown function
Mass (Da):
61054
Number AA:
579
UniProt ID:
Q9NXV6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0001652
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003725
GO:0002039
PhosphoSite+
KinaseNET
Biological Process:
GO:0030308
GO:0009967
GO:0031647
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
Q
E
V
S
E
Y
L
S
Q
N
P
R
V
Site 2
S10
Q
E
V
S
E
Y
L
S
Q
N
P
R
V
A
A
Site 3
S65
D
E
A
A
D
A
E
S
G
T
R
N
R
Q
L
Site 4
S77
R
Q
L
Q
Q
L
I
S
F
S
M
A
W
A
N
Site 5
Y92
H
V
F
L
G
C
R
Y
P
Q
K
V
M
D
K
Site 6
T110
M
A
E
G
I
K
V
T
D
A
P
T
Y
T
T
Site 7
Y115
K
V
T
D
A
P
T
Y
T
T
R
D
E
L
V
Site 8
T116
V
T
D
A
P
T
Y
T
T
R
D
E
L
V
A
Site 9
S131
K
V
K
K
R
G
I
S
S
S
N
E
G
V
E
Site 10
S133
K
K
R
G
I
S
S
S
N
E
G
V
E
E
P
Site 11
S151
R
V
I
E
G
K
N
S
S
A
V
E
Q
D
H
Site 12
S152
V
I
E
G
K
N
S
S
A
V
E
Q
D
H
A
Site 13
T165
H
A
K
T
S
A
K
T
E
R
A
S
A
Q
Q
Site 14
S169
S
A
K
T
E
R
A
S
A
Q
Q
E
N
S
S
Site 15
S175
A
S
A
Q
Q
E
N
S
S
T
C
I
G
S
A
Site 16
S176
S
A
Q
Q
E
N
S
S
T
C
I
G
S
A
I
Site 17
T177
A
Q
Q
E
N
S
S
T
C
I
G
S
A
I
K
Site 18
S181
N
S
S
T
C
I
G
S
A
I
K
S
E
S
G
Site 19
S185
C
I
G
S
A
I
K
S
E
S
G
N
S
A
R
Site 20
S187
G
S
A
I
K
S
E
S
G
N
S
A
R
S
S
Site 21
S190
I
K
S
E
S
G
N
S
A
R
S
S
G
I
S
Site 22
S193
E
S
G
N
S
A
R
S
S
G
I
S
S
Q
N
Site 23
S194
S
G
N
S
A
R
S
S
G
I
S
S
Q
N
S
Site 24
S197
S
A
R
S
S
G
I
S
S
Q
N
S
S
T
S
Site 25
S198
A
R
S
S
G
I
S
S
Q
N
S
S
T
S
D
Site 26
S201
S
G
I
S
S
Q
N
S
S
T
S
D
G
D
R
Site 27
S202
G
I
S
S
Q
N
S
S
T
S
D
G
D
R
S
Site 28
S204
S
S
Q
N
S
S
T
S
D
G
D
R
S
V
S
Site 29
S209
S
T
S
D
G
D
R
S
V
S
S
Q
S
S
S
Site 30
S211
S
D
G
D
R
S
V
S
S
Q
S
S
S
S
V
Site 31
S212
D
G
D
R
S
V
S
S
Q
S
S
S
S
V
S
Site 32
S214
D
R
S
V
S
S
Q
S
S
S
S
V
S
S
Q
Site 33
S215
R
S
V
S
S
Q
S
S
S
S
V
S
S
Q
V
Site 34
S216
S
V
S
S
Q
S
S
S
S
V
S
S
Q
V
T
Site 35
S217
V
S
S
Q
S
S
S
S
V
S
S
Q
V
T
T
Site 36
S219
S
Q
S
S
S
S
V
S
S
Q
V
T
T
A
G
Site 37
S220
Q
S
S
S
S
V
S
S
Q
V
T
T
A
G
S
Site 38
T223
S
S
V
S
S
Q
V
T
T
A
G
S
G
K
A
Site 39
T224
S
V
S
S
Q
V
T
T
A
G
S
G
K
A
S
Site 40
S227
S
A
Q
Q
E
N
S
S
T
C
I
G
S
A
I
Site 41
S231
T
A
G
S
G
K
A
S
E
A
E
A
P
D
K
Site 42
S241
E
A
P
D
K
H
G
S
S
F
V
S
L
L
K
Site 43
S242
A
P
D
K
H
G
S
S
F
V
S
L
L
K
S
Site 44
S245
K
H
G
S
S
F
V
S
L
L
K
S
S
V
N
Site 45
S250
F
V
S
L
L
K
S
S
V
N
S
H
M
T
Q
Site 46
S253
L
L
K
S
S
V
N
S
H
M
T
Q
S
T
D
Site 47
T256
S
S
V
N
S
H
M
T
Q
S
T
D
S
R
Q
Site 48
S261
H
M
T
Q
S
T
D
S
R
Q
Q
S
G
S
P
Site 49
S265
S
T
D
S
R
Q
Q
S
G
S
P
K
K
S
A
Site 50
S267
D
S
R
Q
Q
S
G
S
P
K
K
S
A
L
E
Site 51
S271
Q
S
G
S
P
K
K
S
A
L
E
G
S
S
A
Site 52
S276
K
K
S
A
L
E
G
S
S
A
S
A
S
Q
S
Site 53
S277
K
S
A
L
E
G
S
S
A
S
A
S
Q
S
S
Site 54
S279
A
L
E
G
S
S
A
S
A
S
Q
S
S
S
E
Site 55
S281
E
G
S
S
A
S
A
S
Q
S
S
S
E
I
E
Site 56
S283
S
S
A
S
A
S
Q
S
S
S
E
I
E
V
P
Site 57
S285
A
S
A
S
Q
S
S
S
E
I
E
V
P
L
L
Site 58
S295
E
V
P
L
L
G
S
S
G
S
S
E
V
E
L
Site 59
S306
E
V
E
L
P
L
L
S
S
K
P
S
S
E
T
Site 60
S307
V
E
L
P
L
L
S
S
K
P
S
S
E
T
A
Site 61
S310
P
L
L
S
S
K
P
S
S
E
T
A
S
S
G
Site 62
S311
L
L
S
S
K
P
S
S
E
T
A
S
S
G
L
Site 63
T313
S
S
K
P
S
S
E
T
A
S
S
G
L
T
S
Site 64
S315
K
P
S
S
E
T
A
S
S
G
L
T
S
K
T
Site 65
S316
P
S
S
E
T
A
S
S
G
L
T
S
K
T
S
Site 66
T319
E
T
A
S
S
G
L
T
S
K
T
S
S
E
A
Site 67
S320
T
A
S
S
G
L
T
S
K
T
S
S
E
A
S
Site 68
T322
S
S
G
L
T
S
K
T
S
S
E
A
S
V
S
Site 69
S323
S
G
L
T
S
K
T
S
S
E
A
S
V
S
S
Site 70
S324
G
L
T
S
K
T
S
S
E
A
S
V
S
S
S
Site 71
S327
S
K
T
S
S
E
A
S
V
S
S
S
V
A
K
Site 72
S329
T
S
S
E
A
S
V
S
S
S
V
A
K
N
S
Site 73
S330
S
S
E
A
S
V
S
S
S
V
A
K
N
S
S
Site 74
S331
S
E
A
S
V
S
S
S
V
A
K
N
S
S
S
Site 75
S336
S
S
S
V
A
K
N
S
S
S
S
G
T
S
L
Site 76
S337
S
S
V
A
K
N
S
S
S
S
G
T
S
L
L
Site 77
S338
S
V
A
K
N
S
S
S
S
G
T
S
L
L
T
Site 78
S339
V
A
K
N
S
S
S
S
G
T
S
L
L
T
P
Site 79
T341
K
N
S
S
S
S
G
T
S
L
L
T
P
K
S
Site 80
S342
N
S
S
S
S
G
T
S
L
L
T
P
K
S
S
Site 81
T345
S
S
G
T
S
L
L
T
P
K
S
S
S
S
T
Site 82
S348
T
S
L
L
T
P
K
S
S
S
S
T
N
T
S
Site 83
S349
S
L
L
T
P
K
S
S
S
S
T
N
T
S
L
Site 84
S350
L
L
T
P
K
S
S
S
S
T
N
T
S
L
L
Site 85
S351
L
T
P
K
S
S
S
S
T
N
T
S
L
L
T
Site 86
T352
T
P
K
S
S
S
S
T
N
T
S
L
L
T
S
Site 87
T354
K
S
S
S
S
T
N
T
S
L
L
T
S
K
S
Site 88
S355
S
S
S
S
T
N
T
S
L
L
T
S
K
S
T
Site 89
S359
T
N
T
S
L
L
T
S
K
S
T
S
Q
V
A
Site 90
S361
T
S
L
L
T
S
K
S
T
S
Q
V
A
A
S
Site 91
S368
S
T
S
Q
V
A
A
S
L
L
A
S
K
S
S
Site 92
S372
V
A
A
S
L
L
A
S
K
S
S
S
Q
T
S
Site 93
S374
A
S
L
L
A
S
K
S
S
S
Q
T
S
G
S
Site 94
S375
S
L
L
A
S
K
S
S
S
Q
T
S
G
S
L
Site 95
S376
L
L
A
S
K
S
S
S
Q
T
S
G
S
L
V
Site 96
T378
A
S
K
S
S
S
Q
T
S
G
S
L
V
S
K
Site 97
S379
S
K
S
S
S
Q
T
S
G
S
L
V
S
K
S
Site 98
S381
S
S
S
Q
T
S
G
S
L
V
S
K
S
T
S
Site 99
S384
Q
T
S
G
S
L
V
S
K
S
T
S
L
A
S
Site 100
T387
G
S
L
V
S
K
S
T
S
L
A
S
V
S
Q
Site 101
S391
S
K
S
T
S
L
A
S
V
S
Q
L
A
S
K
Site 102
S393
S
T
S
L
A
S
V
S
Q
L
A
S
K
S
S
Site 103
S397
A
S
V
S
Q
L
A
S
K
S
S
S
Q
T
S
Site 104
S399
V
S
Q
L
A
S
K
S
S
S
Q
T
S
T
S
Site 105
S400
S
Q
L
A
S
K
S
S
S
Q
T
S
T
S
Q
Site 106
S401
Q
L
A
S
K
S
S
S
Q
T
S
T
S
Q
L
Site 107
T403
A
S
K
S
S
S
Q
T
S
T
S
Q
L
P
S
Site 108
S404
S
K
S
S
S
Q
T
S
T
S
Q
L
P
S
K
Site 109
T405
K
S
S
S
Q
T
S
T
S
Q
L
P
S
K
S
Site 110
S406
S
S
S
Q
T
S
T
S
Q
L
P
S
K
S
T
Site 111
S410
T
S
T
S
Q
L
P
S
K
S
T
S
Q
S
S
Site 112
S412
T
S
Q
L
P
S
K
S
T
S
Q
S
S
E
S
Site 113
T413
S
Q
L
P
S
K
S
T
S
Q
S
S
E
S
S
Site 114
S414
Q
L
P
S
K
S
T
S
Q
S
S
E
S
S
V
Site 115
S416
P
S
K
S
T
S
Q
S
S
E
S
S
V
K
F
Site 116
S417
S
K
S
T
S
Q
S
S
E
S
S
V
K
F
S
Site 117
S419
S
T
S
Q
S
S
E
S
S
V
K
F
S
C
K
Site 118
S420
T
S
Q
S
S
E
S
S
V
K
F
S
C
K
L
Site 119
S424
S
E
S
S
V
K
F
S
C
K
L
T
N
E
D
Site 120
T428
V
K
F
S
C
K
L
T
N
E
D
V
K
Q
K
Site 121
Y443
Q
P
F
F
N
R
L
Y
K
T
V
A
W
K
L
Site 122
S495
A
D
L
P
Q
N
K
S
S
Q
E
S
I
V
C
Site 123
S496
D
L
P
Q
N
K
S
S
Q
E
S
I
V
C
E
Site 124
S499
Q
N
K
S
S
Q
E
S
I
V
C
E
L
R
C
Site 125
Y510
E
L
R
C
K
S
V
Y
L
G
T
G
C
G
K
Site 126
S518
L
G
T
G
C
G
K
S
K
E
N
A
K
A
V
Site 127
Y548
V
K
I
C
K
R
K
Y
R
G
S
E
I
E
D
Site 128
S551
C
K
R
K
Y
R
G
S
E
I
E
D
L
V
L
Site 129
S563
L
V
L
L
D
E
E
S
R
P
V
N
L
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation