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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNAJB12
Full Name:
DnaJ homolog subfamily B member 12
Alias:
DJ10; DJB12; DnaJ (Hsp40), subfamily B, 12
Type:
Chaperone membrane protein
Mass (Da):
41860
Number AA:
375
UniProt ID:
Q9NXW2
International Prot ID:
IPI00014400
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0031072
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
L
E
K
A
Q
R
L
Y
P
T
P
R
V
R
A
Site 2
T40
K
A
Q
R
L
Y
P
T
P
R
V
R
A
L
I
Site 3
S49
R
V
R
A
L
I
E
S
L
N
Q
K
P
Q
T
Site 4
T56
S
L
N
Q
K
P
Q
T
A
G
D
Q
P
P
P
Site 5
T64
A
G
D
Q
P
P
P
T
D
T
T
H
A
T
H
Site 6
T66
D
Q
P
P
P
T
D
T
T
H
A
T
H
R
K
Site 7
T70
P
T
D
T
T
H
A
T
H
R
K
A
G
G
T
Site 8
T77
T
H
R
K
A
G
G
T
D
A
P
S
A
N
G
Site 9
S81
A
G
G
T
D
A
P
S
A
N
G
E
A
G
G
Site 10
Y94
G
G
E
S
T
K
G
Y
T
A
E
Q
V
A
A
Site 11
Y111
R
V
K
Q
C
K
D
Y
Y
E
I
L
G
V
S
Site 12
Y112
V
K
Q
C
K
D
Y
Y
E
I
L
G
V
S
R
Site 13
S122
L
G
V
S
R
G
A
S
D
E
D
L
K
K
A
Site 14
Y130
D
E
D
L
K
K
A
Y
R
R
L
A
L
K
F
Site 15
T156
E
A
F
K
A
I
G
T
A
Y
A
V
L
S
N
Site 16
Y158
F
K
A
I
G
T
A
Y
A
V
L
S
N
P
E
Site 17
S162
G
T
A
Y
A
V
L
S
N
P
E
K
R
K
Q
Site 18
Y170
N
P
E
K
R
K
Q
Y
D
Q
F
G
D
D
K
Site 19
S178
D
Q
F
G
D
D
K
S
Q
A
A
R
H
G
H
Site 20
S199
R
G
F
E
A
D
I
S
P
E
D
L
F
N
M
Site 21
S214
F
F
G
G
G
F
P
S
S
N
V
H
V
Y
S
Site 22
S215
F
G
G
G
F
P
S
S
N
V
H
V
Y
S
N
Site 23
Y220
P
S
S
N
V
H
V
Y
S
N
G
R
M
R
Y
Site 24
Y227
Y
S
N
G
R
M
R
Y
T
Y
Q
Q
R
Q
D
Site 25
T228
S
N
G
R
M
R
Y
T
Y
Q
Q
R
Q
D
R
Site 26
Y229
N
G
R
M
R
Y
T
Y
Q
Q
R
Q
D
R
R
Site 27
S269
L
S
Q
L
M
V
S
S
P
P
Y
S
L
S
P
Site 28
Y272
L
M
V
S
S
P
P
Y
S
L
S
P
R
P
S
Site 29
S273
M
V
S
S
P
P
Y
S
L
S
P
R
P
S
V
Site 30
S275
S
S
P
P
Y
S
L
S
P
R
P
S
V
G
H
Site 31
S279
Y
S
L
S
P
R
P
S
V
G
H
I
H
R
R
Site 32
T288
G
H
I
H
R
R
V
T
D
H
L
G
V
V
Y
Site 33
Y296
D
H
L
G
V
V
Y
Y
V
G
D
T
F
S
E
Site 34
T300
V
V
Y
Y
V
G
D
T
F
S
E
E
Y
T
G
Site 35
S302
Y
Y
V
G
D
T
F
S
E
E
Y
T
G
S
S
Site 36
T306
D
T
F
S
E
E
Y
T
G
S
S
L
K
T
V
Site 37
S308
F
S
E
E
Y
T
G
S
S
L
K
T
V
E
R
Site 38
T312
Y
T
G
S
S
L
K
T
V
E
R
N
V
E
D
Site 39
Y321
E
R
N
V
E
D
D
Y
I
A
N
L
R
N
N
Site 40
Y341
Q
Q
K
E
G
L
L
Y
R
A
R
Y
F
G
D
Site 41
Y345
G
L
L
Y
R
A
R
Y
F
G
D
T
D
M
Y
Site 42
Y352
Y
F
G
D
T
D
M
Y
H
R
A
Q
K
M
G
Site 43
T360
H
R
A
Q
K
M
G
T
P
S
C
S
R
L
S
Site 44
S362
A
Q
K
M
G
T
P
S
C
S
R
L
S
E
V
Site 45
S367
T
P
S
C
S
R
L
S
E
V
Q
A
S
L
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation