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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AATF
Full Name:
Protein AATF
Alias:
Apoptosis antagonizing transcription factor; Apoptosis-antagonizing transcription factor; CHE1; CHE-1; DED
Type:
Transcription factor
Mass (Da):
63133
Number AA:
560
UniProt ID:
Q9NY61
International Prot ID:
IPI00783463
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0043522
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
GO:0008624
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
Q
L
L
N
P
R
P
S
E
A
D
P
E
A
D
Site 2
S61
G
S
I
R
K
L
A
S
A
S
L
L
D
T
D
Site 3
S63
I
R
K
L
A
S
A
S
L
L
D
T
D
K
R
Site 4
T67
A
S
A
S
L
L
D
T
D
K
R
Y
C
G
K
Site 5
Y71
L
L
D
T
D
K
R
Y
C
G
K
T
T
S
R
Site 6
T89
N
E
D
H
W
E
Q
T
L
P
G
S
S
D
E
Site 7
S93
W
E
Q
T
L
P
G
S
S
D
E
E
I
S
D
Site 8
S94
E
Q
T
L
P
G
S
S
D
E
E
I
S
D
E
Site 9
S99
G
S
S
D
E
E
I
S
D
E
E
G
S
G
D
Site 10
S104
E
I
S
D
E
E
G
S
G
D
E
D
S
E
G
Site 11
S109
E
G
S
G
D
E
D
S
E
G
L
G
L
E
E
Site 12
Y117
E
G
L
G
L
E
E
Y
D
E
D
D
L
G
A
Site 13
S136
E
C
G
D
H
R
E
S
K
K
S
R
S
H
S
Site 14
S139
D
H
R
E
S
K
K
S
R
S
H
S
A
K
T
Site 15
S141
R
E
S
K
K
S
R
S
H
S
A
K
T
P
G
Site 16
S143
S
K
K
S
R
S
H
S
A
K
T
P
G
F
S
Site 17
T146
S
R
S
H
S
A
K
T
P
G
F
S
V
Q
S
Site 18
S150
S
A
K
T
P
G
F
S
V
Q
S
I
S
D
F
Site 19
S153
T
P
G
F
S
V
Q
S
I
S
D
F
E
K
F
Site 20
S155
G
F
S
V
Q
S
I
S
D
F
E
K
F
T
K
Site 21
S169
K
G
M
D
D
L
G
S
S
E
E
E
E
D
E
Site 22
S178
E
E
E
E
D
E
E
S
G
M
E
E
G
D
D
Site 23
S189
E
G
D
D
A
E
D
S
Q
G
E
S
E
E
D
Site 24
S193
A
E
D
S
Q
G
E
S
E
E
D
R
A
G
D
Site 25
S203
D
R
A
G
D
R
N
S
E
D
D
G
V
V
M
Site 26
T211
E
D
D
G
V
V
M
T
F
S
S
V
K
V
S
Site 27
S213
D
G
V
V
M
T
F
S
S
V
K
V
S
E
E
Site 28
S214
G
V
V
M
T
F
S
S
V
K
V
S
E
E
V
Site 29
S218
T
F
S
S
V
K
V
S
E
E
V
E
K
G
R
Site 30
S272
D
K
G
G
P
E
F
S
S
A
L
K
N
S
H
Site 31
S273
K
G
G
P
E
F
S
S
A
L
K
N
S
H
K
Site 32
S288
A
L
K
A
L
L
R
S
L
V
G
L
Q
E
E
Site 33
Y300
Q
E
E
L
L
F
Q
Y
P
D
T
R
Y
L
V
Site 34
Y305
F
Q
Y
P
D
T
R
Y
L
V
D
G
T
K
P
Site 35
T310
T
R
Y
L
V
D
G
T
K
P
N
A
G
S
E
Site 36
S316
G
T
K
P
N
A
G
S
E
E
I
S
S
E
D
Site 37
S320
N
A
G
S
E
E
I
S
S
E
D
D
E
L
V
Site 38
S321
A
G
S
E
E
I
S
S
E
D
D
E
L
V
E
Site 39
Y348
R
K
L
E
M
E
D
Y
P
S
F
M
A
K
R
Site 40
S350
L
E
M
E
D
Y
P
S
F
M
A
K
R
F
A
Site 41
T360
A
K
R
F
A
D
F
T
V
Y
R
N
R
T
L
Site 42
Y362
R
F
A
D
F
T
V
Y
R
N
R
T
L
Q
K
Site 43
T366
F
T
V
Y
R
N
R
T
L
Q
K
W
H
D
K
Site 44
T374
L
Q
K
W
H
D
K
T
K
L
A
S
G
K
L
Site 45
T410
K
E
R
L
L
R
R
T
Q
T
K
R
S
V
Y
Site 46
T412
R
L
L
R
R
T
Q
T
K
R
S
V
Y
R
V
Site 47
S415
R
R
T
Q
T
K
R
S
V
Y
R
V
L
G
K
Site 48
Y417
T
Q
T
K
R
S
V
Y
R
V
L
G
K
P
E
Site 49
S433
A
A
Q
P
V
P
E
S
L
P
G
E
P
E
I
Site 50
Y464
I
F
D
D
D
D
F
Y
H
Q
L
L
R
E
L
Site 51
T476
R
E
L
I
E
R
K
T
S
S
L
D
P
N
D
Site 52
S477
E
L
I
E
R
K
T
S
S
L
D
P
N
D
Q
Site 53
S478
L
I
E
R
K
T
S
S
L
D
P
N
D
Q
V
Site 54
S510
K
K
V
D
R
K
A
S
K
G
R
K
L
R
F
Site 55
T541
T
M
N
D
D
A
R
T
E
L
Y
R
S
L
F
Site 56
Y544
D
D
A
R
T
E
L
Y
R
S
L
F
G
Q
L
Site 57
S546
A
R
T
E
L
Y
R
S
L
F
G
Q
L
H
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation