KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TUBA8
Full Name:
Tubulin alpha-8 chain
Alias:
Alpha-tubulin 8; TUBAL2; Tubulin alpha chain-like 2; Tubulin alpha-8; Tubulin, alpha-8
Type:
Cytoskeletal protein
Mass (Da):
50094
Number AA:
449
UniProt ID:
Q9NY65
International Prot ID:
IPI00646909
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0043234
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0051258
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
H
G
I
Q
A
D
G
T
F
D
A
Q
A
S
K
Site 2
S48
S
K
I
N
D
D
D
S
F
T
T
F
F
S
E
Site 3
T50
I
N
D
D
D
S
F
T
T
F
F
S
E
T
G
Site 4
T51
N
D
D
D
S
F
T
T
F
F
S
E
T
G
N
Site 5
S54
D
S
F
T
T
F
F
S
E
T
G
N
G
K
H
Site 6
T82
V
D
E
V
R
A
G
T
Y
R
Q
L
F
H
P
Site 7
T94
F
H
P
E
Q
L
I
T
G
K
E
D
A
A
N
Site 8
Y103
K
E
D
A
A
N
N
Y
A
R
G
H
Y
T
V
Site 9
Y108
N
N
Y
A
R
G
H
Y
T
V
G
K
E
S
I
Site 10
T109
N
Y
A
R
G
H
Y
T
V
G
K
E
S
I
D
Site 11
T126
L
D
R
I
R
K
L
T
D
A
C
S
G
L
Q
Site 12
S158
S
L
L
M
E
R
L
S
L
D
Y
G
K
K
S
Site 13
Y161
M
E
R
L
S
L
D
Y
G
K
K
S
K
L
E
Site 14
S165
S
L
D
Y
G
K
K
S
K
L
E
F
A
I
Y
Site 15
Y172
S
K
L
E
F
A
I
Y
P
A
P
Q
V
S
T
Site 16
Y185
S
T
A
V
V
E
P
Y
N
S
I
L
T
T
H
Site 17
S187
A
V
V
E
P
Y
N
S
I
L
T
T
H
T
T
Site 18
T190
E
P
Y
N
S
I
L
T
T
H
T
T
L
E
H
Site 19
T191
P
Y
N
S
I
L
T
T
H
T
T
L
E
H
S
Site 20
T193
N
S
I
L
T
T
H
T
T
L
E
H
S
D
C
Site 21
T194
S
I
L
T
T
H
T
T
L
E
H
S
D
C
A
Site 22
S198
T
H
T
T
L
E
H
S
D
C
A
F
M
V
D
Site 23
Y210
M
V
D
N
E
A
I
Y
D
I
C
R
R
N
L
Site 24
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Site 25
Y224
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
I
Site 26
T225
D
I
E
R
P
T
Y
T
N
L
N
R
L
I
S
Site 27
S232
T
N
L
N
R
L
I
S
Q
I
V
S
S
I
T
Site 28
S236
R
L
I
S
Q
I
V
S
S
I
T
A
S
L
R
Site 29
S237
L
I
S
Q
I
V
S
S
I
T
A
S
L
R
F
Site 30
T239
S
Q
I
V
S
S
I
T
A
S
L
R
F
D
G
Site 31
S241
I
V
S
S
I
T
A
S
L
R
F
D
G
A
L
Site 32
Y262
F
Q
T
N
L
V
P
Y
P
R
I
H
F
P
L
Site 33
Y282
I
I
S
A
E
K
A
Y
H
E
Q
L
S
V
A
Site 34
S287
K
A
Y
H
E
Q
L
S
V
A
E
I
T
S
S
Site 35
S293
L
S
V
A
E
I
T
S
S
C
F
E
P
N
S
Site 36
S294
S
V
A
E
I
T
S
S
C
F
E
P
N
S
Q
Site 37
S300
S
S
C
F
E
P
N
S
Q
M
V
K
C
D
P
Site 38
T337
V
A
I
A
A
I
K
T
K
R
T
I
Q
F
V
Site 39
T340
A
A
I
K
T
K
R
T
I
Q
F
V
D
W
C
Site 40
T349
Q
F
V
D
W
C
P
T
G
F
K
V
G
I
N
Site 41
Y357
G
F
K
V
G
I
N
Y
Q
P
P
T
V
V
P
Site 42
T361
G
I
N
Y
Q
P
P
T
V
V
P
G
G
D
L
Site 43
S379
Q
R
A
V
C
M
L
S
N
T
T
A
I
A
E
Site 44
Y399
D
H
K
F
D
L
M
Y
A
K
R
A
F
V
H
Site 45
Y408
K
R
A
F
V
H
W
Y
V
G
E
G
M
E
E
Site 46
S419
G
M
E
E
G
E
F
S
E
A
R
E
D
L
A
Site 47
Y432
L
A
A
L
E
K
D
Y
E
E
V
G
T
D
S
Site 48
T437
K
D
Y
E
E
V
G
T
D
S
F
E
E
E
N
Site 49
S439
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation