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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC5A4
Full Name:
Low affinity sodium-glucose cotransporter
Alias:
Sodium/glucose cotransporter 3;Solute carrier family 5 member 4
Type:
Mass (Da):
72456
Number AA:
659
UniProt ID:
Q9NY91
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
S
T
V
S
P
S
T
I
A
E
T
P
E
P
Site 2
T13
S
P
S
T
I
A
E
T
P
E
P
P
P
L
S
Site 3
S20
T
P
E
P
P
P
L
S
D
H
I
R
N
A
A
Site 4
T50
G
L
W
A
M
L
K
T
N
R
G
T
I
G
G
Site 5
S77
M
G
A
S
L
F
A
S
N
I
G
S
N
H
Y
Site 6
Y84
S
N
I
G
S
N
H
Y
V
G
L
A
G
T
G
Site 7
T127
Y
I
K
S
G
V
M
T
M
P
E
Y
L
K
K
Site 8
Y131
G
V
M
T
M
P
E
Y
L
K
K
R
F
G
G
Site 9
S149
Q
V
Y
L
S
I
L
S
L
F
I
C
V
V
L
Site 10
Y229
A
F
N
E
V
G
G
Y
E
S
F
T
E
K
Y
Site 11
S231
N
E
V
G
G
Y
E
S
F
T
E
K
Y
V
N
Site 12
Y236
Y
E
S
F
T
E
K
Y
V
N
A
T
P
S
V
Site 13
T240
T
E
K
Y
V
N
A
T
P
S
V
V
E
G
D
Site 14
S242
K
Y
V
N
A
T
P
S
V
V
E
G
D
N
L
Site 15
S252
E
G
D
N
L
T
I
S
A
S
C
Y
T
P
R
Site 16
S254
D
N
L
T
I
S
A
S
C
Y
T
P
R
A
D
Site 17
Y256
L
T
I
S
A
S
C
Y
T
P
R
A
D
S
F
Site 18
T257
T
I
S
A
S
C
Y
T
P
R
A
D
S
F
H
Site 19
Y410
T
L
F
T
I
D
L
Y
T
K
M
R
K
Q
A
Site 20
T411
L
F
T
I
D
L
Y
T
K
M
R
K
Q
A
S
Site 21
S418
T
K
M
R
K
Q
A
S
E
K
E
L
L
I
A
Site 22
Y455
Q
N
G
Q
L
I
H
Y
T
E
S
I
S
S
Y
Site 23
T456
N
G
Q
L
I
H
Y
T
E
S
I
S
S
Y
L
Site 24
S458
Q
L
I
H
Y
T
E
S
I
S
S
Y
L
G
P
Site 25
S460
I
H
Y
T
E
S
I
S
S
Y
L
G
P
P
I
Site 26
S461
H
Y
T
E
S
I
S
S
Y
L
G
P
P
I
A
Site 27
S566
L
C
W
V
L
R
N
S
T
E
E
R
I
D
I
Site 28
T567
C
W
V
L
R
N
S
T
E
E
R
I
D
I
D
Site 29
S579
D
I
D
A
E
E
K
S
Q
E
E
T
D
D
G
Site 30
T583
E
E
K
S
Q
E
E
T
D
D
G
V
E
E
D
Site 31
Y591
D
D
G
V
E
E
D
Y
P
E
K
S
R
G
C
Site 32
Y603
R
G
C
L
K
K
A
Y
D
L
F
C
G
L
Q
Site 33
T628
E
A
L
S
K
K
L
T
D
T
S
E
R
P
S
Site 34
T630
L
S
K
K
L
T
D
T
S
E
R
P
S
W
R
Site 35
S631
S
K
K
L
T
D
T
S
E
R
P
S
W
R
T
Site 36
S635
T
D
T
S
E
R
P
S
W
R
T
I
V
N
I
Site 37
T638
S
E
R
P
S
W
R
T
I
V
N
I
N
A
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation