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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX56
Full Name:
Probable ATP-dependent RNA helicase DDX56
Alias:
ATP-dependent 61 kDa nucleolar RNA helicase; DDX21; DEAD (Asp-Glu-Ala-Asp) box polypeptide 56; DEAD box protein 56; EC 3.6.1.-; NOH61
Type:
Helicase
Mass (Da):
61590
Number AA:
547
UniProt ID:
Q9NY93
International Prot ID:
IPI00302281
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004004
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
P
R
L
L
Q
A
V
T
D
L
G
W
S
R
P
Site 2
T31
D
L
G
W
S
R
P
T
L
I
Q
E
K
A
I
Site 3
T53
D
L
L
A
R
A
R
T
G
S
G
K
T
A
A
Site 4
S55
L
A
R
A
R
T
G
S
G
K
T
A
A
Y
A
Site 5
T91
R
G
L
V
L
V
P
T
K
E
L
A
R
Q
A
Site 6
Y108
M
I
Q
Q
L
A
T
Y
C
A
R
D
V
R
V
Site 7
S119
D
V
R
V
A
N
V
S
A
A
E
D
S
V
S
Site 8
S124
N
V
S
A
A
E
D
S
V
S
Q
R
A
V
L
Site 9
S126
S
A
A
E
D
S
V
S
Q
R
A
V
L
M
E
Site 10
T141
K
P
D
V
V
V
G
T
P
S
R
I
L
S
H
Site 11
S147
G
T
P
S
R
I
L
S
H
L
Q
Q
D
S
L
Site 12
S153
L
S
H
L
Q
Q
D
S
L
K
L
R
D
S
L
Site 13
S173
D
E
A
D
L
L
F
S
F
G
F
E
E
E
L
Site 14
S182
G
F
E
E
E
L
K
S
L
L
C
H
L
P
R
Site 15
T217
L
I
L
H
N
P
V
T
L
K
L
Q
E
S
Q
Site 16
S223
V
T
L
K
L
Q
E
S
Q
L
P
G
P
D
Q
Site 17
T267
K
S
L
L
F
V
N
T
L
E
R
S
Y
R
L
Site 18
Y272
V
N
T
L
E
R
S
Y
R
L
R
L
F
L
E
Site 19
S296
N
G
E
L
P
L
R
S
R
C
H
I
I
S
Q
Site 20
Y309
S
Q
F
N
Q
G
F
Y
D
C
V
I
A
T
D
Site 21
S339
G
P
K
G
D
K
A
S
D
P
E
A
G
V
A
Site 22
T365
L
N
F
D
L
P
P
T
P
E
A
Y
I
H
R
Site 23
Y369
L
P
P
T
P
E
A
Y
I
H
R
A
G
R
T
Site 24
S405
G
K
I
E
E
L
L
S
G
E
N
R
G
P
I
Site 25
Y416
R
G
P
I
L
L
P
Y
Q
F
R
M
E
E
I
Site 26
Y428
E
E
I
E
G
F
R
Y
R
C
R
D
A
M
R
Site 27
S436
R
C
R
D
A
M
R
S
V
T
K
Q
A
I
R
Site 28
T438
R
D
A
M
R
S
V
T
K
Q
A
I
R
E
A
Site 29
S457
I
K
E
E
L
L
H
S
E
K
L
K
T
Y
F
Site 30
T462
L
H
S
E
K
L
K
T
Y
F
E
D
N
P
R
Site 31
Y463
H
S
E
K
L
K
T
Y
F
E
D
N
P
R
D
Site 32
S516
K
K
R
K
K
L
S
S
S
C
R
K
A
K
R
Site 33
S517
K
R
K
K
L
S
S
S
C
R
K
A
K
R
A
Site 34
S526
R
K
A
K
R
A
K
S
Q
N
P
L
R
S
F
Site 35
S532
K
S
Q
N
P
L
R
S
F
K
H
K
G
K
K
Site 36
T543
K
G
K
K
F
R
P
T
A
K
P
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation