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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TERF2IP
Full Name:
Telomeric repeat-binding factor 2-interacting protein 1
Alias:
hRap1; RAP1; TE2I; TE2IP; Telomeric repeat binding factor 2 interacting protein 1; telomeric repeat binding factor 2, interacting protein; TRF2- interacting telomeric protein Rap1; TRF2-interacting telomeric protein Rap1
Type:
DNA replication protein
Mass (Da):
44260
Number AA:
399
UniProt ID:
Q9NYB0
International Prot ID:
IPI00008961
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030870
GO:0005737
GO:0000783
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0003697
PhosphoSite+
KinaseNET
Biological Process:
GO:0032205
GO:0031848
GO:0070198
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
G
K
D
P
N
G
P
T
H
S
S
T
L
F
V
Site 2
S17
D
P
N
G
P
T
H
S
S
T
L
F
V
R
D
Site 3
T19
N
G
P
T
H
S
S
T
L
F
V
R
D
D
G
Site 4
S27
L
F
V
R
D
D
G
S
S
M
S
F
Y
V
R
Site 5
S28
F
V
R
D
D
G
S
S
M
S
F
Y
V
R
P
Site 6
S30
R
D
D
G
S
S
M
S
F
Y
V
R
P
S
P
Site 7
Y32
D
G
S
S
M
S
F
Y
V
R
P
S
P
A
K
Site 8
S36
M
S
F
Y
V
R
P
S
P
A
K
R
R
L
S
Site 9
S43
S
P
A
K
R
R
L
S
T
L
I
L
H
G
G
Site 10
T44
P
A
K
R
R
L
S
T
L
I
L
H
G
G
G
Site 11
S75
G
E
A
L
A
E
A
S
G
D
F
I
S
T
Q
Site 12
S80
E
A
S
G
D
F
I
S
T
Q
Y
I
L
D
C
Site 13
Y99
E
R
L
E
L
E
A
Y
R
L
G
P
A
S
A
Site 14
S105
A
Y
R
L
G
P
A
S
A
A
D
T
G
S
E
Site 15
T109
G
P
A
S
A
A
D
T
G
S
E
A
K
P
G
Site 16
S111
A
S
A
A
D
T
G
S
E
A
K
P
G
A
L
Site 17
T146
A
D
D
V
A
I
L
T
Y
V
K
E
N
A
R
Site 18
Y147
D
D
V
A
I
L
T
Y
V
K
E
N
A
R
S
Site 19
S154
Y
V
K
E
N
A
R
S
P
S
S
V
T
G
N
Site 20
S156
K
E
N
A
R
S
P
S
S
V
T
G
N
A
L
Site 21
S157
E
N
A
R
S
P
S
S
V
T
G
N
A
L
W
Site 22
T173
A
M
E
K
S
S
L
T
Q
H
S
W
Q
S
L
Site 23
S176
K
S
S
L
T
Q
H
S
W
Q
S
L
K
D
R
Site 24
S179
L
T
Q
H
S
W
Q
S
L
K
D
R
Y
L
K
Site 25
Y184
W
Q
S
L
K
D
R
Y
L
K
H
L
R
G
Q
Site 26
Y195
L
R
G
Q
E
H
K
Y
L
L
G
D
A
P
V
Site 27
S203
L
L
G
D
A
P
V
S
P
S
S
Q
K
L
K
Site 28
S205
G
D
A
P
V
S
P
S
S
Q
K
L
K
R
K
Site 29
S206
D
A
P
V
S
P
S
S
Q
K
L
K
R
K
A
Site 30
S222
E
D
P
E
A
A
D
S
G
E
P
Q
N
K
R
Site 31
T230
G
E
P
Q
N
K
R
T
P
D
L
P
E
E
E
Site 32
Y238
P
D
L
P
E
E
E
Y
V
K
E
E
I
Q
E
Site 33
S269
E
E
V
V
V
D
E
S
P
P
D
F
E
I
H
Site 34
T286
M
C
D
D
D
P
P
T
P
E
E
D
S
E
T
Site 35
S291
P
P
T
P
E
E
D
S
E
T
Q
P
D
E
E
Site 36
T293
T
P
E
E
D
S
E
T
Q
P
D
E
E
E
E
Site 37
S307
E
E
E
E
E
K
V
S
Q
P
E
V
G
A
A
Site 38
T346
N
S
G
E
L
E
A
T
S
A
F
L
A
S
G
Site 39
S347
S
G
E
L
E
A
T
S
A
F
L
A
S
G
Q
Site 40
Y359
S
G
Q
R
A
D
G
Y
P
I
W
S
R
Q
D
Site 41
T377
L
Q
K
D
D
E
D
T
R
E
A
L
V
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation