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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABI2
Full Name:
Abl interactor 2
Alias:
Abelson interactor 2; ABI-2; ABI2B; Abl binding protein 3; Abl-binding protein 3; AblBP3; Abl-interactor 2; AIP-1; Arg binding protein 1; Arg-binding protein 1; ArgBP1; ARGBPIA; SSH3BP2
Type:
Regulator protein; Cytoplasm, cytosol, lamellipodium, filopodium, cytoskeleton protein
Mass (Da):
55663
Number AA:
513
UniProt ID:
Q9NYB9
International Prot ID:
IPI00442210
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005829
GO:0030175
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0017124
GO:0005070
PhosphoSite+
KinaseNET
Biological Process:
GO:0008154
GO:0016477
GO:0018108
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
G
R
R
A
L
F
D
S
Y
T
N
L
E
R
V
Site 2
Y23
R
R
A
L
F
D
S
Y
T
N
L
E
R
V
A
Site 3
T24
R
A
L
F
D
S
Y
T
N
L
E
R
V
A
D
Site 4
Y32
N
L
E
R
V
A
D
Y
C
E
N
N
Y
I
Q
Site 5
T50
K
Q
R
A
L
E
E
T
K
A
Y
T
T
Q
S
Site 6
Y53
A
L
E
E
T
K
A
Y
T
T
Q
S
L
A
S
Site 7
S81
Q
M
L
D
I
Q
A
S
Q
L
R
R
M
E
S
Site 8
S88
S
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
Site 9
S89
Q
L
R
R
M
E
S
S
I
N
H
I
S
Q
T
Site 10
S94
E
S
S
I
N
H
I
S
Q
T
V
D
I
H
K
Site 11
T113
R
R
E
I
G
I
L
T
T
N
K
N
T
S
R
Site 12
Y136
N
L
E
R
P
V
R
Y
I
R
K
P
I
D
Y
Site 13
Y143
Y
I
R
K
P
I
D
Y
T
I
L
D
D
I
G
Site 14
T144
I
R
K
P
I
D
Y
T
I
L
D
D
I
G
H
Site 15
S162
W
L
L
R
F
K
V
S
T
Q
N
M
K
M
G
Site 16
T163
L
L
R
F
K
V
S
T
Q
N
M
K
M
G
G
Site 17
T174
K
M
G
G
L
P
R
T
T
P
P
T
Q
K
P
Site 18
T175
M
G
G
L
P
R
T
T
P
P
T
Q
K
P
P
Site 19
T178
L
P
R
T
T
P
P
T
Q
K
P
P
S
P
P
Site 20
S183
P
P
T
Q
K
P
P
S
P
P
M
S
G
K
G
Site 21
S187
K
P
P
S
P
P
M
S
G
K
G
T
L
G
R
Site 22
T191
P
P
M
S
G
K
G
T
L
G
R
H
S
P
Y
Site 23
S196
K
G
T
L
G
R
H
S
P
Y
R
T
L
E
P
Site 24
Y198
T
L
G
R
H
S
P
Y
R
T
L
E
P
V
R
Site 25
T200
G
R
H
S
P
Y
R
T
L
E
P
V
R
P
P
Site 26
Y213
P
P
V
V
P
N
D
Y
V
P
S
P
T
R
N
Site 27
S216
V
P
N
D
Y
V
P
S
P
T
R
N
M
A
P
Site 28
T218
N
D
Y
V
P
S
P
T
R
N
M
A
P
S
Q
Site 29
S224
P
T
R
N
M
A
P
S
Q
Q
S
P
V
R
T
Site 30
S227
N
M
A
P
S
Q
Q
S
P
V
R
T
A
S
V
Site 31
T231
S
Q
Q
S
P
V
R
T
A
S
V
N
Q
R
N
Site 32
S233
Q
S
P
V
R
T
A
S
V
N
Q
R
N
R
T
Site 33
T240
S
V
N
Q
R
N
R
T
Y
S
S
S
G
S
S
Site 34
Y241
V
N
Q
R
N
R
T
Y
S
S
S
G
S
S
G
Site 35
S242
N
Q
R
N
R
T
Y
S
S
S
G
S
S
G
G
Site 36
S243
Q
R
N
R
T
Y
S
S
S
G
S
S
G
G
S
Site 37
S244
R
N
R
T
Y
S
S
S
G
S
S
G
G
S
H
Site 38
S246
R
T
Y
S
S
S
G
S
S
G
G
S
H
P
S
Site 39
S247
T
Y
S
S
S
G
S
S
G
G
S
H
P
S
S
Site 40
S250
S
S
G
S
S
G
G
S
H
P
S
S
R
S
S
Site 41
S253
S
S
G
G
S
H
P
S
S
R
S
S
S
R
E
Site 42
S254
S
G
G
S
H
P
S
S
R
S
S
S
R
E
N
Site 43
S256
G
S
H
P
S
S
R
S
S
S
R
E
N
S
G
Site 44
S257
S
H
P
S
S
R
S
S
S
R
E
N
S
G
S
Site 45
S258
H
P
S
S
R
S
S
S
R
E
N
S
G
S
G
Site 46
S262
R
S
S
S
R
E
N
S
G
S
G
S
V
G
V
Site 47
S264
S
S
R
E
N
S
G
S
G
S
V
G
V
P
I
Site 48
S266
R
E
N
S
G
S
G
S
V
G
V
P
I
A
V
Site 49
T291
A
P
A
G
S
A
G
T
P
P
L
P
A
T
S
Site 50
T297
G
T
P
P
L
P
A
T
S
A
S
A
P
A
P
Site 51
S312
L
V
P
A
T
V
P
S
S
T
A
P
N
A
A
Site 52
T314
P
A
T
V
P
S
S
T
A
P
N
A
A
A
G
Site 53
T331
P
N
L
A
D
G
F
T
S
P
T
P
P
V
V
Site 54
S332
N
L
A
D
G
F
T
S
P
T
P
P
V
V
S
Site 55
T334
A
D
G
F
T
S
P
T
P
P
V
V
S
S
T
Site 56
S339
S
P
T
P
P
V
V
S
S
T
P
P
T
G
H
Site 57
S340
P
T
P
P
V
V
S
S
T
P
P
T
G
H
P
Site 58
T341
T
P
P
V
V
S
S
T
P
P
T
G
H
P
V
Site 59
T344
V
V
S
S
T
P
P
T
G
H
P
V
Q
F
Y
Site 60
Y351
T
G
H
P
V
Q
F
Y
S
M
N
R
P
A
S
Site 61
S352
G
H
P
V
Q
F
Y
S
M
N
R
P
A
S
R
Site 62
S358
Y
S
M
N
R
P
A
S
R
H
T
P
P
T
I
Site 63
T361
N
R
P
A
S
R
H
T
P
P
T
I
G
G
S
Site 64
T364
A
S
R
H
T
P
P
T
I
G
G
S
L
P
Y
Site 65
S368
T
P
P
T
I
G
G
S
L
P
Y
R
R
P
P
Site 66
Y371
T
I
G
G
S
L
P
Y
R
R
P
P
S
I
T
Site 67
S376
L
P
Y
R
R
P
P
S
I
T
S
Q
T
S
L
Site 68
T378
Y
R
R
P
P
S
I
T
S
Q
T
S
L
Q
N
Site 69
S379
R
R
P
P
S
I
T
S
Q
T
S
L
Q
N
Q
Site 70
S382
P
S
I
T
S
Q
T
S
L
Q
N
Q
M
N
G
Site 71
Y393
Q
M
N
G
G
P
F
Y
S
Q
N
P
V
S
D
Site 72
S394
M
N
G
G
P
F
Y
S
Q
N
P
V
S
D
T
Site 73
S399
F
Y
S
Q
N
P
V
S
D
T
P
P
P
P
P
Site 74
T401
S
Q
N
P
V
S
D
T
P
P
P
P
P
P
V
Site 75
S416
E
E
P
V
F
D
E
S
P
P
P
P
P
P
P
Site 76
Y426
P
P
P
P
P
E
D
Y
E
E
E
E
A
A
V
Site 77
Y436
E
E
A
A
V
V
E
Y
S
D
P
Y
A
E
E
Site 78
Y440
V
V
E
Y
S
D
P
Y
A
E
E
D
P
P
W
Site 79
S451
D
P
P
W
A
P
R
S
Y
L
E
K
V
V
A
Site 80
Y452
P
P
W
A
P
R
S
Y
L
E
K
V
V
A
I
Site 81
Y460
L
E
K
V
V
A
I
Y
D
Y
T
K
D
K
E
Site 82
Y462
K
V
V
A
I
Y
D
Y
T
K
D
K
E
D
E
Site 83
T463
V
V
A
I
Y
D
Y
T
K
D
K
E
D
E
L
Site 84
S471
K
D
K
E
D
E
L
S
F
Q
E
G
A
I
I
Site 85
Y479
F
Q
E
G
A
I
I
Y
V
I
K
K
N
D
D
Site 86
Y489
K
K
N
D
D
G
W
Y
E
G
V
M
N
G
V
Site 87
Y504
T
G
L
F
P
G
N
Y
V
E
S
I
M
H
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation