KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
C5orf6
Full Name:
Protein FAM53C
Alias:
Chromosome 5 open reading frame 6; FA53C; FAM53C; Family with sequence similarity 53, member C; Putative nuclear protein; STSG4523
Type:
Mass (Da):
43091
Number AA:
392
UniProt ID:
Q9NYF3
International Prot ID:
IPI00009900
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
I
T
L
I
T
E
Q
L
Q
K
Q
T
Site 2
T13
T
E
Q
L
Q
K
Q
T
L
D
E
L
K
C
T
Site 3
T20
T
L
D
E
L
K
C
T
R
F
S
I
S
L
P
Site 4
S23
E
L
K
C
T
R
F
S
I
S
L
P
L
P
D
Site 5
S25
K
C
T
R
F
S
I
S
L
P
L
P
D
H
A
Site 6
S40
D
I
S
N
C
G
N
S
F
Q
L
V
S
E
G
Site 7
S45
G
N
S
F
Q
L
V
S
E
G
A
S
W
R
G
Site 8
S49
Q
L
V
S
E
G
A
S
W
R
G
L
P
H
C
Site 9
S64
S
C
A
E
F
Q
D
S
L
N
F
S
Y
H
P
Site 10
S68
F
Q
D
S
L
N
F
S
Y
H
P
S
G
L
S
Site 11
Y69
Q
D
S
L
N
F
S
Y
H
P
S
G
L
S
L
Site 12
S72
L
N
F
S
Y
H
P
S
G
L
S
L
H
L
R
Site 13
S75
S
Y
H
P
S
G
L
S
L
H
L
R
P
P
S
Site 14
S82
S
L
H
L
R
P
P
S
R
G
N
S
P
K
E
Site 15
S86
R
P
P
S
R
G
N
S
P
K
E
Q
P
F
S
Site 16
S93
S
P
K
E
Q
P
F
S
Q
V
L
R
P
E
P
Site 17
S114
P
V
P
P
A
P
P
S
K
R
H
C
R
S
L
Site 18
S120
P
S
K
R
H
C
R
S
L
S
V
P
V
D
L
Site 19
S122
K
R
H
C
R
S
L
S
V
P
V
D
L
S
R
Site 20
S128
L
S
V
P
V
D
L
S
R
W
Q
P
V
W
R
Site 21
S139
P
V
W
R
P
A
P
S
K
L
W
T
P
I
K
Site 22
T143
P
A
P
S
K
L
W
T
P
I
K
H
R
G
S
Site 23
S150
T
P
I
K
H
R
G
S
G
G
G
G
G
P
Q
Site 24
S162
G
P
Q
V
P
H
Q
S
P
P
K
R
V
S
S
Site 25
S168
Q
S
P
P
K
R
V
S
S
L
R
F
L
Q
A
Site 26
S169
S
P
P
K
R
V
S
S
L
R
F
L
Q
A
P
Site 27
S177
L
R
F
L
Q
A
P
S
A
S
S
Q
C
A
P
Site 28
S180
L
Q
A
P
S
A
S
S
Q
C
A
P
A
H
R
Site 29
Y189
C
A
P
A
H
R
P
Y
S
P
P
F
F
S
L
Site 30
S190
A
P
A
H
R
P
Y
S
P
P
F
F
S
L
A
Site 31
S195
P
Y
S
P
P
F
F
S
L
A
L
A
Q
D
S
Site 32
S202
S
L
A
L
A
Q
D
S
S
R
P
C
A
A
S
Site 33
S203
L
A
L
A
Q
D
S
S
R
P
C
A
A
S
P
Site 34
S209
S
S
R
P
C
A
A
S
P
Q
S
G
S
W
E
Site 35
S212
P
C
A
A
S
P
Q
S
G
S
W
E
S
D
A
Site 36
S214
A
A
S
P
Q
S
G
S
W
E
S
D
A
E
S
Site 37
S217
P
Q
S
G
S
W
E
S
D
A
E
S
L
S
P
Site 38
S221
S
W
E
S
D
A
E
S
L
S
P
C
P
P
Q
Site 39
S223
E
S
D
A
E
S
L
S
P
C
P
P
Q
R
R
Site 40
S232
C
P
P
Q
R
R
F
S
L
S
P
S
L
G
P
Site 41
S234
P
Q
R
R
F
S
L
S
P
S
L
G
P
Q
A
Site 42
S236
R
R
F
S
L
S
P
S
L
G
P
Q
A
S
R
Site 43
S242
P
S
L
G
P
Q
A
S
R
F
L
P
S
A
R
Site 44
S247
Q
A
S
R
F
L
P
S
A
R
S
S
P
A
S
Site 45
S250
R
F
L
P
S
A
R
S
S
P
A
S
S
P
E
Site 46
S251
F
L
P
S
A
R
S
S
P
A
S
S
P
E
L
Site 47
S254
S
A
R
S
S
P
A
S
S
P
E
L
P
W
R
Site 48
S255
A
R
S
S
P
A
S
S
P
E
L
P
W
R
P
Site 49
S271
G
L
R
N
L
P
R
S
R
S
Q
P
C
D
L
Site 50
S273
R
N
L
P
R
S
R
S
Q
P
C
D
L
D
A
Site 51
T283
C
D
L
D
A
R
K
T
G
V
K
R
R
H
E
Site 52
S299
D
P
R
R
L
R
P
S
L
D
F
D
K
M
N
Site 53
S311
K
M
N
Q
K
P
Y
S
G
G
L
C
L
Q
E
Site 54
T319
G
G
L
C
L
Q
E
T
A
R
E
G
S
S
I
Site 55
S324
Q
E
T
A
R
E
G
S
S
I
S
P
P
W
F
Site 56
S325
E
T
A
R
E
G
S
S
I
S
P
P
W
F
M
Site 57
S327
A
R
E
G
S
S
I
S
P
P
W
F
M
A
C
Site 58
S340
A
C
S
P
P
P
L
S
A
S
C
S
P
T
G
Site 59
S342
S
P
P
P
L
S
A
S
C
S
P
T
G
G
S
Site 60
S344
P
P
L
S
A
S
C
S
P
T
G
G
S
S
Q
Site 61
S350
C
S
P
T
G
G
S
S
Q
V
L
S
E
S
E
Site 62
S354
G
G
S
S
Q
V
L
S
E
S
E
E
E
E
E
Site 63
S356
S
S
Q
V
L
S
E
S
E
E
E
E
E
G
A
Site 64
S372
R
W
G
R
Q
A
L
S
K
R
T
L
C
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation