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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C5orf5
Full Name:
Protein FAM13B
Alias:
CE005; GAP-like protein N61; KHCHP
Type:
Intracellular protein
Mass (Da):
104543
Number AA:
915
UniProt ID:
Q9NYF5
International Prot ID:
IPI00009899
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
R
K
S
S
S
P
S
L
S
N
C
Site 2
S6
_
_
M
R
K
S
S
S
P
S
L
S
N
C
N
Site 3
S8
M
R
K
S
S
S
P
S
L
S
N
C
N
S
V
Site 4
S10
K
S
S
S
P
S
L
S
N
C
N
S
V
L
A
Site 5
Y77
V
E
W
L
R
Q
R
Y
D
S
G
E
E
V
D
Site 6
S79
W
L
R
Q
R
Y
D
S
G
E
E
V
D
L
V
Site 7
Y125
L
M
Q
L
S
Q
D
Y
N
N
E
D
E
F
G
Site 8
S162
R
F
L
A
N
V
A
S
H
H
E
E
I
W
S
Site 9
S169
S
H
H
E
E
I
W
S
A
N
S
L
A
A
V
Site 10
Y185
G
P
D
V
F
H
I
Y
T
D
V
E
D
M
K
Site 11
Y208
M
A
G
L
L
E
N
Y
Y
E
F
F
E
N
E
Site 12
Y209
A
G
L
L
E
N
Y
Y
E
F
F
E
N
E
E
Site 13
S220
E
N
E
E
E
D
F
S
S
N
D
L
S
S
I
Site 14
S221
N
E
E
E
D
F
S
S
N
D
L
S
S
I
T
Site 15
S225
D
F
S
S
N
D
L
S
S
I
T
E
Q
V
N
Site 16
S226
F
S
S
N
D
L
S
S
I
T
E
Q
V
N
E
Site 17
S258
P
E
E
G
A
E
K
S
N
D
M
P
E
V
V
Site 18
T270
E
V
V
Q
L
R
M
T
E
N
I
L
E
S
N
Site 19
S276
M
T
E
N
I
L
E
S
N
S
V
T
A
T
S
Site 20
S278
E
N
I
L
E
S
N
S
V
T
A
T
S
T
H
Site 21
T280
I
L
E
S
N
S
V
T
A
T
S
T
H
I
S
Site 22
T282
E
S
N
S
V
T
A
T
S
T
H
I
S
P
I
Site 23
S283
S
N
S
V
T
A
T
S
T
H
I
S
P
I
S
Site 24
T302
S
T
D
I
L
E
R
T
I
R
A
A
V
E
Q
Site 25
S316
Q
H
L
F
D
L
Q
S
S
I
D
H
D
L
K
Site 26
S329
L
K
N
L
Q
Q
Q
S
V
V
C
N
N
E
A
Site 27
S360
A
D
D
I
I
N
A
S
E
S
N
R
D
C
S
Site 28
S362
D
I
I
N
A
S
E
S
N
R
D
C
S
K
P
Site 29
S367
S
E
S
N
R
D
C
S
K
P
V
A
S
T
N
Site 30
S394
E
N
E
E
N
T
Q
S
V
G
I
L
L
E
P
Site 31
S403
G
I
L
L
E
P
C
S
D
R
G
D
S
E
D
Site 32
S408
P
C
S
D
R
G
D
S
E
D
G
C
L
E
R
Site 33
Y418
G
C
L
E
R
E
E
Y
L
L
F
D
S
D
K
Site 34
S423
E
E
Y
L
L
F
D
S
D
K
L
S
H
L
I
Site 35
S427
L
F
D
S
D
K
L
S
H
L
I
L
D
S
S
Site 36
S434
S
H
L
I
L
D
S
S
S
K
I
C
D
L
N
Site 37
S446
D
L
N
A
N
T
E
S
E
V
P
G
G
Q
S
Site 38
S453
S
E
V
P
G
G
Q
S
V
G
V
Q
G
E
A
Site 39
S474
H
L
D
L
K
N
V
S
D
G
D
K
W
E
E
Site 40
S488
E
P
F
P
A
F
K
S
W
Q
E
D
S
E
S
Site 41
S493
F
K
S
W
Q
E
D
S
E
S
G
E
A
Q
L
Site 42
S495
S
W
Q
E
D
S
E
S
G
E
A
Q
L
S
P
Site 43
S501
E
S
G
E
A
Q
L
S
P
Q
A
G
R
M
N
Site 44
S521
E
D
C
P
P
V
L
S
H
R
S
L
D
F
G
Site 45
S524
P
P
V
L
S
H
R
S
L
D
F
G
Q
S
Q
Site 46
S530
R
S
L
D
F
G
Q
S
Q
R
F
L
H
D
P
Site 47
S542
H
D
P
E
K
L
D
S
S
S
K
A
L
S
F
Site 48
S543
D
P
E
K
L
D
S
S
S
K
A
L
S
F
T
Site 49
S544
P
E
K
L
D
S
S
S
K
A
L
S
F
T
R
Site 50
S548
D
S
S
S
K
A
L
S
F
T
R
I
R
R
S
Site 51
T550
S
S
K
A
L
S
F
T
R
I
R
R
S
S
F
Site 52
S555
S
F
T
R
I
R
R
S
S
F
S
S
K
D
E
Site 53
S556
F
T
R
I
R
R
S
S
F
S
S
K
D
E
K
Site 54
S558
R
I
R
R
S
S
F
S
S
K
D
E
K
R
E
Site 55
S559
I
R
R
S
S
F
S
S
K
D
E
K
R
E
D
Site 56
T568
D
E
K
R
E
D
R
T
P
Y
Q
L
V
K
K
Site 57
Y570
K
R
E
D
R
T
P
Y
Q
L
V
K
K
L
Q
Site 58
S593
Q
F
E
R
E
R
N
S
K
P
S
Y
S
D
I
Site 59
S596
R
E
R
N
S
K
P
S
Y
S
D
I
A
A
N
Site 60
Y597
E
R
N
S
K
P
S
Y
S
D
I
A
A
N
P
Site 61
S598
R
N
S
K
P
S
Y
S
D
I
A
A
N
P
K
Site 62
T614
L
K
W
M
T
E
L
T
K
L
R
K
Q
I
K
Site 63
S628
K
D
A
K
H
K
N
S
D
G
E
F
V
P
Q
Site 64
T636
D
G
E
F
V
P
Q
T
R
P
R
S
N
T
L
Site 65
S640
V
P
Q
T
R
P
R
S
N
T
L
P
K
S
F
Site 66
T642
Q
T
R
P
R
S
N
T
L
P
K
S
F
G
S
Site 67
S646
R
S
N
T
L
P
K
S
F
G
S
S
L
D
H
Site 68
S650
L
P
K
S
F
G
S
S
L
D
H
E
D
E
E
Site 69
T676
K
K
P
S
K
E
A
T
L
E
L
I
L
K
R
Site 70
S711
H
L
V
E
E
K
A
S
L
Q
K
S
L
L
Y
Site 71
S715
E
K
A
S
L
Q
K
S
L
L
Y
Y
E
S
Q
Site 72
Y718
S
L
Q
K
S
L
L
Y
Y
E
S
Q
H
G
R
Site 73
Y719
L
Q
K
S
L
L
Y
Y
E
S
Q
H
G
R
P
Site 74
S721
K
S
L
L
Y
Y
E
S
Q
H
G
R
P
V
T
Site 75
T728
S
Q
H
G
R
P
V
T
K
E
E
R
H
I
V
Site 76
Y739
R
H
I
V
K
P
L
Y
D
R
Y
R
L
V
K
Site 77
Y742
V
K
P
L
Y
D
R
Y
R
L
V
K
Q
M
L
Site 78
S760
S
I
T
P
V
L
G
S
P
S
T
K
R
R
G
Site 79
S762
T
P
V
L
G
S
P
S
T
K
R
R
G
Q
M
Site 80
T763
P
V
L
G
S
P
S
T
K
R
R
G
Q
M
L
Site 81
S797
E
D
G
V
N
L
S
S
E
L
G
D
M
L
K
Site 82
T805
E
L
G
D
M
L
K
T
A
V
Q
V
Q
S
S
Site 83
S812
T
A
V
Q
V
Q
S
S
L
E
N
S
E
S
D
Site 84
S816
V
Q
S
S
L
E
N
S
E
S
D
V
E
E
N
Site 85
S818
S
S
L
E
N
S
E
S
D
V
E
E
N
Q
E
Site 86
S835
A
L
D
L
R
L
S
S
S
R
A
A
S
M
P
Site 87
S836
L
D
L
R
L
S
S
S
R
A
A
S
M
P
E
Site 88
S840
L
S
S
S
R
A
A
S
M
P
E
L
L
E
Q
Site 89
T861
E
K
K
K
L
R
K
T
L
R
E
F
E
E
A
Site 90
Y870
R
E
F
E
E
A
F
Y
Q
Q
N
G
R
N
A
Site 91
Y889
R
V
P
V
L
E
E
Y
R
E
Y
K
K
I
K
Site 92
Y892
V
L
E
E
Y
R
E
Y
K
K
I
K
A
K
L
Site 93
S907
R
L
L
E
V
L
I
S
K
Q
D
S
S
K
S
Site 94
S911
V
L
I
S
K
Q
D
S
S
K
S
I
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation