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Updated November 2019
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Protein Info
Short Name:
RASL12
Full Name:
Ras-like protein family member 12
Alias:
Ras-like protein Ris
Type:
Mass (Da):
29662
Number AA:
266
UniProt ID:
Q9NYN1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
F
G
K
P
R
A
G
S
G
P
Q
S
A
P
L
Site 2
S16
R
A
G
S
G
P
Q
S
A
P
L
E
V
N
L
Site 3
S34
G
R
R
G
A
G
K
S
A
L
T
V
K
F
L
Site 4
T37
G
A
G
K
S
A
L
T
V
K
F
L
T
K
R
Site 5
S47
F
L
T
K
R
F
I
S
E
Y
D
P
N
L
E
Site 6
Y49
T
K
R
F
I
S
E
Y
D
P
N
L
E
D
T
Site 7
T56
Y
D
P
N
L
E
D
T
Y
S
S
E
E
T
V
Site 8
Y57
D
P
N
L
E
D
T
Y
S
S
E
E
T
V
D
Site 9
S58
P
N
L
E
D
T
Y
S
S
E
E
T
V
D
H
Site 10
S59
N
L
E
D
T
Y
S
S
E
E
T
V
D
H
Q
Site 11
T62
D
T
Y
S
S
E
E
T
V
D
H
Q
P
V
H
Site 12
T75
V
H
L
R
V
M
D
T
A
D
L
D
T
P
R
Site 13
T80
M
D
T
A
D
L
D
T
P
R
N
C
E
R
Y
Site 14
S102
L
V
V
Y
S
V
D
S
R
Q
S
F
D
S
S
Site 15
S105
Y
S
V
D
S
R
Q
S
F
D
S
S
S
S
Y
Site 16
S108
D
S
R
Q
S
F
D
S
S
S
S
Y
L
E
L
Site 17
S109
S
R
Q
S
F
D
S
S
S
S
Y
L
E
L
L
Site 18
S110
R
Q
S
F
D
S
S
S
S
Y
L
E
L
L
A
Site 19
S111
Q
S
F
D
S
S
S
S
Y
L
E
L
L
A
L
Site 20
Y112
S
F
D
S
S
S
S
Y
L
E
L
L
A
L
H
Site 21
T123
L
A
L
H
A
K
E
T
Q
R
S
I
P
A
L
Site 22
S126
H
A
K
E
T
Q
R
S
I
P
A
L
L
L
G
Site 23
T145
M
A
Q
Y
R
Q
V
T
K
A
E
G
V
A
L
Site 24
S190
A
R
R
E
L
E
K
S
P
L
T
R
P
L
F
Site 25
T193
E
L
E
K
S
P
L
T
R
P
L
F
I
S
E
Site 26
S199
L
T
R
P
L
F
I
S
E
E
R
A
L
P
H
Site 27
T211
L
P
H
Q
A
P
L
T
A
R
H
G
L
A
S
Site 28
S218
T
A
R
H
G
L
A
S
C
T
F
N
T
L
S
Site 29
T242
V
A
Q
A
K
L
V
T
V
K
S
S
R
A
Q
Site 30
S245
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Site 31
S250
V
K
S
S
R
A
Q
S
K
R
K
A
P
T
L
Site 32
T258
K
R
K
A
P
T
L
T
L
L
K
G
F
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation