PhosphoNET

           
Protein Info 
   
Short Name:  CELSR1
Full Name:  Cadherin EGF LAG seven-pass G-type receptor 1
Alias:  Cadherin EGF LAG seven-pass G-type receptor 1; Cadherin, EGF LAG seven-pass G-type receptor 1; Cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); CDHF9; CELR1; Flamingo homolog 2; Flamingo homologue 2; FMI2; HFmi2; ME2; Protocadherin flamingo 2
Type:  Receptor, GPCR
Mass (Da):  329486
Number AA:  3014
UniProt ID:  Q9NYQ6
International Prot ID:  IPI00003384
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0004930  GO:0005509  GO:0046983 PhosphoSite+ KinaseNET
Biological Process:  GO:0007417  GO:0001736  GO:0007156 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T57YAVGAACTPRAPREL
Site 2S80LAGRRRVSGAGRPLP
Site 3S96QVRLVARSAPTALSR
Site 4S102RSAPTALSRRLRART
Site 5T109SRRLRARTHLPGCGA
Site 6T207LEAATAGTPSASPSP
Site 7S209AATAGTPSASPSPSP
Site 8S211TAGTPSASPSPSPPL
Site 9S213GTPSASPSPSPPLPP
Site 10S215PSASPSPSPPLPPNL
Site 11T237ARRARRGTSGRGSLK
Site 12S238RRARRGTSGRGSLKF
Site 13S242RGTSGRGSLKFPMPN
Site 14Y250LKFPMPNYQVALFEN
Site 15S281EGEEERVSYYMEGLF
Site 16Y282GEEERVSYYMEGLFD
Site 17Y283EEERVSYYMEGLFDE
Site 18S292EGLFDERSRGYFRID
Site 19Y295FDERSRGYFRIDSAT
Site 20S300RGYFRIDSATGAVST
Site 21T302YFRIDSATGAVSTDS
Site 22S306DSATGAVSTDSVLDR
Site 23S309TGAVSTDSVLDRETK
Site 24T315DSVLDRETKETHVLR
Site 25T318LDRETKETHVLRVKA
Site 26Y328LRVKAVDYSTPPRSA
Site 27S329RVKAVDYSTPPRSAT
Site 28T330VKAVDYSTPPRSATT
Site 29S334DYSTPPRSATTYITV
Site 30Y338PPRSATTYITVLVKD
Site 31T340RSATTYITVLVKDTN
Site 32S350VKDTNDHSPVFEQSE
Site 33S356HSPVFEQSEYRERVR
Site 34Y358PVFEQSEYRERVREN
Site 35T374EVGYEVLTIRASDRD
Site 36S378EVLTIRASDRDSPIN
Site 37S382IRASDRDSPINANLR
Site 38Y390PINANLRYRVLGGAW
Site 39S405DVFQLNESSGVVSTR
Site 40S406VFQLNESSGVVSTRA
Site 41S410NESSGVVSTRAVLDR
Site 42Y423DREEAAEYQLLVEAN
Site 43S440GRNPGPLSATATVYI
Site 44Y446LSATATVYIEVEDEN
Site 45Y456VEDENDNYPQFSEQN
Site 46Y464PQFSEQNYVVQVPED
Site 47T484AVLRVQATDRDQGQN
Site 48S531FEDVQKYSLSIKAQD
Site 49S533DVQKYSLSIKAQDGG
Site 50S594IQAVDADSGENARLH
Site 51Y602GENARLHYRLVDTAS
Site 52T625GPKNPAPTPDFPFQI
Site 53T640HNSSGWITVCAELDR
Site 54Y653DREEVEHYSFGVEAV
Site 55S654REEVEHYSFGVEAVD
Site 56S664VEAVDHGSPPMSSST
Site 57S668DHGSPPMSSSTSVSI
Site 58S669HGSPPMSSSTSVSIT
Site 59S670GSPPMSSSTSVSITV
Site 60T676SSTSVSITVLDVNDN
Site 61Y692PVFTQPTYELRLNED
Site 62T708AVGSSVLTLQARDRD
Site 63S718ARDRDANSVITYQLT
Site 64Y722DANSVITYQLTGGNT
Site 65S736TRNRFALSSQRGGGL
Site 66S737RNRFALSSQRGGGLI
Site 67Y752TLALPLDYKQEQQYV
Site 68Y758DYKQEQQYVLAVTAS
Site 69S765YVLAVTASDGTRSHT
Site 70S770TASDGTRSHTAHVLI
Site 71T772SDGTRSHTAHVLINV
Site 72T784INVTDANTHRPVFQS
Site 73S791THRPVFQSSHYTVSV
Site 74S792HRPVFQSSHYTVSVS
Site 75Y794PVFQSSHYTVSVSED
Site 76T795VFQSSHYTVSVSEDR
Site 77S797QSSHYTVSVSEDRPV
Site 78S807EDRPVGTSIATLSAN
Site 79S812GTSIATLSANDEDTG
Site 80T818LSANDEDTGENARIT
Site 81T825TGENARITYVIQDPV
Site 82Y826GENARITYVIQDPVP
Site 83T843RIDPDSGTMYTMMEL
Site 84Y845DPDSGTMYTMMELDY
Site 85Y852YTMMELDYENQVAYT
Site 86S873DNGIPQKSDTTTLEI
Site 87T877PQKSDTTTLEILILD
Site 88Y897PQFLWDFYQGSIFED
Site 89S910EDAPPSTSILQVSAT
Site 90S915STSILQVSATDRDSG
Site 91T917SILQVSATDRDSGPN
Site 92S921VSATDRDSGPNGRLL
Site 93Y929GPNGRLLYTFQGGDD
Site 94T930PNGRLLYTFQGGDDG
Site 95Y942DDGDGDFYIEPTSGV
Site 96S947DFYIEPTSGVIRTQR
Site 97T952PTSGVIRTQRRLDRE
Site 98S975ALAVDRGSPTPLSAS
Site 99T977AVDRGSPTPLSASVE
Site 100S980RGSPTPLSASVEIQV
Site 101Y1036GPNAQIMYQIVEGDM
Site 102Y1070DFEVRREYVLVVQAT
Site 103Y1111FQILFNNYVTNKSNS
Site 104S1116NNYVTNKSNSFPTGV
Site 105S1118YVTNKSNSFPTGVIG
Site 106S1135PAHDPDVSDSLNYTF
Site 107S1137HDPDVSDSLNYTFVQ
Site 108Y1140DVSDSLNYTFVQGNE
Site 109T1141VSDSLNYTFVQGNEL
Site 110S1163ATGELQLSRDLDNNR
Site 111S1206TDDMLTNSITVRLEN
Site 112T1208DMLTNSITVRLENMS
Site 113S1215TVRLENMSQEKFLSP
Site 114T1251VFNVQNDTDVSSNIL
Site 115Y1285EDLQEQIYLNRTLLT
Site 116Y1315LREPCENYMKCVSVL
Site 117S1320ENYMKCVSVLRFDSS
Site 118S1326VSVLRFDSSAPFLSS
Site 119T1334SAPFLSSTTVLFRPI
Site 120Y1359PPGFTGDYCETEIDL
Site 121Y1368ETEIDLCYSDPCGAN
Site 122S1380GANGRCRSREGGYTC
Site 123T1386RSREGGYTCECFEDF
Site 124Y1435CVCPPGEYERPYCEV
Site 125Y1439PGEYERPYCEVTTRS
Site 126T1443ERPYCEVTTRSFPPQ
Site 127S1446YCEVTTRSFPPQSFV
Site 128S1451TRSFPPQSFVTFRGL
Site 129T1454FPPQSFVTFRGLRQR
Site 130S1467QRFHFTISLTFATQE
Site 131T1469FHFTISLTFATQERN
Site 132Y1481ERNGLLLYNGRFNEK
Site 133T1504VDEQVQLTFSAGETT
Site 134T1513SAGETTTTVAPKVPS
Site 135S1523PKVPSGVSDGRWHSV
Site 136Y1535HSVQVQYYNKPNIGH
Site 137T1565TVDDCDTTMAVRFGK
Site 138Y1577FGKDIGNYSCAAQGT
Site 139S1578GKDIGNYSCAAQGTQ
Site 140S1591TQTGSKKSLDLTGPL
Site 141S1625VGCMRNLSVDGKNVD
Site 142S1695MPHPQLFSGESVVSW
Site 143S1698PQLFSGESVVSWSDL
Site 144S1726FRTRKEDSVLMEATS
Site 145S1733SVLMEATSGGPTSFR
Site 146S1738ATSGGPTSFRLQILN
Site 147Y1747RLQILNNYLQFEVSH
Site 148S1753NYLQFEVSHGPSDVE
Site 149S1761HGPSDVESVMLSGLR
Site 150T1770MLSGLRVTDGEWHHL
Site 151S1788LKNVKEDSEMKHLVT
Site 152Y1800LVTMTLDYGMDQNKA
Site 153S1832GASEDKVSVRRGFRG
Site 154T1849QGVRMGGTPTNVATL
Site 155T1877CDVDDPCTSSPCPPN
Site 156S1878DVDDPCTSSPCPPNS
Site 157S1879VDDPCTSSPCPPNSR
Site 158Y1894CHDAWEDYSCVCDKG
Site 159S1925NMGACVRSPGSPQGY
Site 160S1928ACVRSPGSPQGYVCE
Site 161Y1932SPGSPQGYVCECGPS
Site 162Y1944GPSHYGPYCENKLDL
Site 163T2014PHGSHSRTCDMATGQ
Site 164T2044DNPFAEVTTLGCEVI
Site 165Y2052TLGCEVIYNGCPKAF
Site 166S2091GNAVRHCSGEKGWLP
Site 167S2120RAMNEKLSRNETQVD
Site 168T2124EKLSRNETQVDGARA
Site 169T2142VRALRSATQHTGTLF
Site 170T2155LFGNDVRTAYQLLGH
Site 171T2213IQRSEGGTAQLLRRL
Site 172Y2223LLRRLEGYFSNVARN
Site 173S2225RRLEGYFSNVARNVR
Site 174T2234VARNVRRTYLRPFVI
Site 175Y2235ARNVRRTYLRPFVIV
Site 176T2268ARVPRFDTIHEEFPR
Site 177S2279EFPRELESSVSFPAD
Site 178S2280FPRELESSVSFPADF
Site 179S2282RELESSVSFPADFFR
Site 180T2306LRPAGRRTTPQTTRP
Site 181T2307RPAGRRTTPQTTRPG
Site 182T2310GRRTTPQTTRPGPGT
Site 183T2317TTRPGPGTEREAPIS
Site 184S2324TEREAPISRRRRHPD
Site 185S2361RYDPDRRSLRLPHRP
Site 186S2435ARGCELLSRNRTHVA
Site 187T2439ELLSRNRTHVACQCS
Site 188S2458FAVLMDISRRENGEV
Site 189S2498SLVRMLRSNLHSIHK
Site 190S2502MLRSNLHSIHKHLAV
Site 191T2561LHVYRMLTEVRNIDT
Site 192T2568TEVRNIDTGPMRFYY
Site 193Y2597VGLDPQGYGNPDFCW
Site 194S2633NTVTSVLSAKVSCQR
Site 195S2637SVLSAKVSCQRKHHY
Site 196Y2644SCQRKHHYYGKKGIV
Site 197Y2645CQRKHHYYGKKGIVS
Site 198S2726RKLHLEDSATTRATL
Site 199T2728LHLEDSATTRATLLT
Site 200T2732DSATTRATLLTRSLN
Site 201T2735TTRATLLTRSLNCNT
Site 202T2743RSLNCNTTFGDGPDM
Site 203T2753DGPDMLRTDLGESTA
Site 204S2758LRTDLGESTASLDSI
Site 205S2761DLGESTASLDSIVRD
Site 206S2764ESTASLDSIVRDEGI
Site 207S2784SSGLVRGSHGEPDAS
Site 208S2791SHGEPDASLMPRSCK
Site 209S2796DASLMPRSCKDPPGH
Site 210S2805KDPPGHDSDSDSELS
Site 211S2807PPGHDSDSDSELSLD
Site 212S2809GHDSDSDSELSLDEQ
Site 213S2812SDSDSELSLDEQSSS
Site 214S2817ELSLDEQSSSYASSH
Site 215S2818LSLDEQSSSYASSHS
Site 216S2819SLDEQSSSYASSHSS
Site 217Y2820LDEQSSSYASSHSSD
Site 218S2822EQSSSYASSHSSDSE
Site 219S2823QSSSYASSHSSDSED
Site 220S2825SSYASSHSSDSEDDG
Site 221S2826SYASSHSSDSEDDGV
Site 222S2828ASSHSSDSEDDGVGA
Site 223S2848PARGAVHSTPKGDAV
Site 224T2849ARGAVHSTPKGDAVA
Site 225S2867PAGWPDQSLAESDSE
Site 226S2871PDQSLAESDSEDPSG
Site 227S2873QSLAESDSEDPSGKP
Site 228S2877ESDSEDPSGKPRLKV
Site 229T2886KPRLKVETKVSVELH
Site 230S2889LKVETKVSVELHREE
Site 231S2899LHREEQGSHRGEYPP
Site 232Y2904QGSHRGEYPPDQESG
Site 233S2918GGAARLASSQPPEQR
Site 234S2919GAARLASSQPPEQRK
Site 235T2940VTYPPPLTLTEQTLK
Site 236S2960KLADCEQSPTSSRTS
Site 237T2962ADCEQSPTSSRTSSL
Site 238S2963DCEQSPTSSRTSSLG
Site 239S2964CEQSPTSSRTSSLGS
Site 240S2967SPTSSRTSSLGSGGP
Site 241S2968PTSSRTSSLGSGGPD
Site 242S2971SRTSSLGSGGPDCAI
Site 243T2979GGPDCAITVKSPGRE
Site 244S2982DCAITVKSPGREPGR
Site 245S3003AMNVRTGSAQADGSD
Site 246S3009GSAQADGSDSEKP__
Site 247S3011AQADGSDSEKP____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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