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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAT2
Full Name:
Protocadherin Fat 2
Alias:
CDHF8; FAT tumor suppressor 2; HFat2; HFAT2; MEGF1; Multiple epidermal growth factor-like domains 1; Protocadherin Fat 2 cadherin family member 8
Type:
Cell surface protein
Mass (Da):
479392
Number AA:
4349
UniProt ID:
Q9NYQ8
International Prot ID:
IPI00302641
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0016020
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007156
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y153
P
L
F
S
P
P
S
Y
R
V
T
I
S
E
D
Site 2
Y395
P
A
F
P
N
L
Q
Y
V
L
K
P
S
S
E
Site 3
T412
G
F
K
L
N
A
R
T
G
L
I
T
T
T
K
Site 4
S885
T
G
H
L
D
R
E
S
E
P
R
Y
I
L
K
Site 5
Y889
D
R
E
S
E
P
R
Y
I
L
K
V
E
A
R
Site 6
T1410
V
I
A
R
P
L
D
T
R
R
R
S
N
Y
N
Site 7
Y1592
G
V
N
A
E
V
H
Y
S
L
L
K
G
N
S
Site 8
Y1708
G
V
F
S
M
N
S
Y
S
G
L
I
S
T
Q
Site 9
Y2139
D
Y
Q
A
L
N
K
Y
H
L
K
V
I
A
R
Site 10
S2155
G
G
T
P
S
L
Q
S
E
E
E
V
L
V
T
Site 11
Y2205
P
E
G
L
R
L
I
Y
N
I
V
E
E
E
P
Site 12
Y2233
T
V
T
G
P
L
D
Y
E
S
K
T
K
H
V
Site 13
S2593
K
A
S
E
Y
T
V
S
I
Q
S
N
V
S
K
Site 14
S2596
E
Y
T
V
S
I
Q
S
N
V
S
K
D
S
P
Site 15
S2599
V
S
I
Q
S
N
V
S
K
D
S
P
V
I
Q
Site 16
S2908
D
N
A
P
R
F
A
S
E
E
Y
R
G
S
V
Site 17
Y2911
P
R
F
A
S
E
E
Y
R
G
S
V
V
E
N
Site 18
S2914
A
S
E
E
Y
R
G
S
V
V
E
N
S
E
P
Site 19
S2919
R
G
S
V
V
E
N
S
E
P
G
E
L
V
A
Site 20
T2927
E
P
G
E
L
V
A
T
L
K
T
L
D
A
D
Site 21
Y3274
D
A
R
T
G
I
L
Y
V
N
A
S
L
D
F
Site 22
T3815
I
L
L
F
T
N
E
T
A
S
V
S
L
K
L
Site 23
S3819
T
N
E
T
A
S
V
S
L
K
L
A
S
G
V
Site 24
S3870
S
I
R
L
M
V
D
S
M
G
N
T
S
L
V
Site 25
T3874
M
V
D
S
M
G
N
T
S
L
V
V
P
E
N
Site 26
Y4069
S
T
V
G
L
L
F
Y
C
R
R
C
K
S
H
Site 27
S4090
D
P
D
L
L
A
R
S
V
G
V
D
T
Q
A
Site 28
S4109
E
L
N
P
L
S
A
S
S
C
N
N
L
N
Q
Site 29
S4110
L
N
P
L
S
A
S
S
C
N
N
L
N
Q
P
Site 30
S4120
N
L
N
Q
P
E
P
S
K
A
S
V
P
N
E
Site 31
S4123
Q
P
E
P
S
K
A
S
V
P
N
E
L
V
T
Site 32
T4130
S
V
P
N
E
L
V
T
F
G
P
N
S
K
Q
Site 33
S4135
L
V
T
F
G
P
N
S
K
Q
R
P
V
V
C
Site 34
S4143
K
Q
R
P
V
V
C
S
V
P
P
R
L
P
P
Site 35
S4155
L
P
P
A
A
V
P
S
H
S
D
N
E
P
V
Site 36
S4157
P
A
A
V
P
S
H
S
D
N
E
P
V
I
K
Site 37
S4168
P
V
I
K
R
T
W
S
S
E
E
M
V
Y
P
Site 38
Y4185
A
M
V
W
P
P
T
Y
S
R
N
E
R
W
E
Site 39
Y4193
S
R
N
E
R
W
E
Y
P
H
S
E
V
T
Q
Site 40
S4196
E
R
W
E
Y
P
H
S
E
V
T
Q
G
P
L
Site 41
T4199
E
Y
P
H
S
E
V
T
Q
G
P
L
P
P
S
Site 42
S4206
T
Q
G
P
L
P
P
S
A
H
R
H
S
T
P
Site 43
S4211
P
P
S
A
H
R
H
S
T
P
V
V
M
P
E
Site 44
T4212
P
S
A
H
R
H
S
T
P
V
V
M
P
E
P
Site 45
Y4223
M
P
E
P
N
G
L
Y
G
G
F
P
F
P
L
Site 46
Y4243
R
A
P
L
P
P
R
Y
S
N
Q
N
L
E
D
Site 47
S4244
A
P
L
P
P
R
Y
S
N
Q
N
L
E
D
L
Site 48
S4254
N
L
E
D
L
M
P
S
R
P
P
S
P
R
E
Site 49
S4258
L
M
P
S
R
P
P
S
P
R
E
R
L
V
A
Site 50
Y4277
E
Y
T
A
I
S
Y
Y
H
S
Q
F
R
Q
G
Site 51
S4279
T
A
I
S
Y
Y
H
S
Q
F
R
Q
G
G
G
Site 52
S4303
K
G
V
G
M
R
L
S
R
A
G
P
S
Y
A
Site 53
Y4309
L
S
R
A
G
P
S
Y
A
V
C
E
V
E
G
Site 54
Y4331
Q
P
R
V
P
P
N
Y
E
G
S
D
M
V
E
Site 55
S4334
V
P
P
N
Y
E
G
S
D
M
V
E
S
D
Y
Site 56
S4339
E
G
S
D
M
V
E
S
D
Y
G
S
C
E
E
Site 57
Y4341
S
D
M
V
E
S
D
Y
G
S
C
E
E
V
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation