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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UGGT1
Full Name:
UDP-glucose:glycoprotein glucosyltransferase 1
Alias:
GT; HUGT1; UDP-Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose glycoprotein glucosyltransferase 1; UGCGL1; UGGG1; UGGT; UGT1; UGTR
Type:
EC 2.4.1.-; Transferase
Mass (Da):
177190
Number AA:
1555
UniProt ID:
Q9NYU2
International Prot ID:
IPI00619903
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005793
GO:0005788
Uniprot
OncoNet
Molecular Function:
GO:0003980
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0051084
GO:0006486
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
F
S
S
V
K
A
D
S
K
A
I
T
T
S
L
Site 2
T48
K
A
D
S
K
A
I
T
T
S
L
T
T
K
W
Site 3
S50
D
S
K
A
I
T
T
S
L
T
T
K
W
F
S
Site 4
T52
K
A
I
T
T
S
L
T
T
K
W
F
S
T
P
Site 5
S72
S
E
F
L
A
E
D
S
Q
E
K
F
W
N
F
Site 6
S89
A
S
Q
N
I
G
S
S
D
H
D
G
T
D
Y
Site 7
T94
G
S
S
D
H
D
G
T
D
Y
S
Y
Y
H
A
Site 8
Y96
S
D
H
D
G
T
D
Y
S
Y
Y
H
A
I
L
Site 9
Y98
H
D
G
T
D
Y
S
Y
Y
H
A
I
L
E
A
Site 10
Y99
D
G
T
D
Y
S
Y
Y
H
A
I
L
E
A
A
Site 11
T130
S
L
R
S
Y
S
A
T
I
Q
A
F
Q
Q
I
Site 12
S149
P
P
P
E
G
C
N
S
F
F
S
V
H
G
K
Site 13
S161
H
G
K
K
T
C
E
S
D
T
L
E
A
L
L
Site 14
T163
K
K
T
C
E
S
D
T
L
E
A
L
L
L
T
Site 15
Y186
L
F
K
G
D
H
R
Y
P
S
S
N
P
E
S
Site 16
S188
K
G
D
H
R
Y
P
S
S
N
P
E
S
P
V
Site 17
S189
G
D
H
R
Y
P
S
S
N
P
E
S
P
V
V
Site 18
S193
Y
P
S
S
N
P
E
S
P
V
V
I
F
Y
S
Site 19
Y199
E
S
P
V
V
I
F
Y
S
E
I
G
S
E
E
Site 20
S204
I
F
Y
S
E
I
G
S
E
E
F
S
N
F
H
Site 21
S208
E
I
G
S
E
E
F
S
N
F
H
R
Q
L
I
Site 22
S216
N
F
H
R
Q
L
I
S
K
S
N
A
G
K
I
Site 23
S218
H
R
Q
L
I
S
K
S
N
A
G
K
I
N
Y
Site 24
Y225
S
N
A
G
K
I
N
Y
V
F
R
H
Y
I
F
Site 25
Y230
I
N
Y
V
F
R
H
Y
I
F
N
P
R
K
E
Site 26
Y240
N
P
R
K
E
P
V
Y
L
S
G
Y
G
V
E
Site 27
S242
R
K
E
P
V
Y
L
S
G
Y
G
V
E
L
A
Site 28
Y244
E
P
V
Y
L
S
G
Y
G
V
E
L
A
I
K
Site 29
S252
G
V
E
L
A
I
K
S
T
E
Y
K
A
K
D
Site 30
T261
E
Y
K
A
K
D
D
T
Q
V
K
G
T
E
V
Site 31
T271
K
G
T
E
V
N
T
T
V
I
G
E
N
D
P
Site 32
S350
L
V
V
M
K
D
L
S
Q
N
F
P
T
K
A
Site 33
T361
P
T
K
A
R
A
I
T
K
T
A
V
S
S
E
Site 34
T363
K
A
R
A
I
T
K
T
A
V
S
S
E
L
R
Site 35
T371
A
V
S
S
E
L
R
T
E
V
E
E
N
Q
K
Site 36
Y379
E
V
E
E
N
Q
K
Y
F
K
G
T
L
G
L
Site 37
S445
L
K
L
N
I
Q
P
S
E
A
D
Y
A
V
D
Site 38
Y449
I
Q
P
S
E
A
D
Y
A
V
D
I
R
S
P
Site 39
S455
D
Y
A
V
D
I
R
S
P
A
I
S
W
V
N
Site 40
S459
D
I
R
S
P
A
I
S
W
V
N
N
L
E
V
Site 41
S468
V
N
N
L
E
V
D
S
R
Y
N
S
W
P
S
Site 42
Y470
N
L
E
V
D
S
R
Y
N
S
W
P
S
S
L
Site 43
S472
E
V
D
S
R
Y
N
S
W
P
S
S
L
Q
E
Site 44
S476
R
Y
N
S
W
P
S
S
L
Q
E
L
L
R
P
Site 45
T484
L
Q
E
L
L
R
P
T
F
P
G
V
I
R
Q
Site 46
T516
T
T
A
E
L
M
N
T
A
E
M
F
L
S
N
Site 47
Y557
A
V
L
R
A
Y
N
Y
V
A
Q
E
V
D
D
Site 48
Y565
V
A
Q
E
V
D
D
Y
H
A
F
Q
T
L
T
Site 49
S591
V
K
V
E
H
V
V
S
V
L
E
K
K
Y
P
Site 50
Y597
V
S
V
L
E
K
K
Y
P
Y
V
E
V
N
S
Site 51
S610
N
S
I
L
G
I
D
S
A
Y
D
R
N
R
K
Site 52
Y612
I
L
G
I
D
S
A
Y
D
R
N
R
K
E
A
Site 53
Y622
N
R
K
E
A
R
G
Y
Y
E
Q
T
G
V
G
Site 54
Y623
R
K
E
A
R
G
Y
Y
E
Q
T
G
V
G
P
Site 55
T664
H
K
I
L
E
T
T
T
F
F
Q
R
A
V
Y
Site 56
Y671
T
F
F
Q
R
A
V
Y
L
G
E
L
P
H
D
Site 57
Y684
H
D
Q
D
V
V
E
Y
I
M
N
Q
P
N
V
Site 58
S697
N
V
V
P
R
I
N
S
R
I
L
T
A
E
R
Site 59
T701
R
I
N
S
R
I
L
T
A
E
R
D
Y
L
D
Site 60
Y706
I
L
T
A
E
R
D
Y
L
D
L
T
A
S
N
Site 61
T710
E
R
D
Y
L
D
L
T
A
S
N
N
F
F
V
Site 62
S712
D
Y
L
D
L
T
A
S
N
N
F
F
V
D
D
Site 63
Y720
N
N
F
F
V
D
D
Y
A
R
F
T
I
L
D
Site 64
T724
V
D
D
Y
A
R
F
T
I
L
D
S
Q
G
K
Site 65
Y741
A
V
A
N
S
M
N
Y
L
T
K
K
G
M
S
Site 66
T743
A
N
S
M
N
Y
L
T
K
K
G
M
S
S
K
Site 67
S748
Y
L
T
K
K
G
M
S
S
K
E
I
Y
D
D
Site 68
Y753
G
M
S
S
K
E
I
Y
D
D
S
F
I
R
P
Site 69
S756
S
K
E
I
Y
D
D
S
F
I
R
P
V
T
F
Site 70
S771
W
I
V
G
D
F
D
S
P
S
G
R
Q
L
L
Site 71
S773
V
G
D
F
D
S
P
S
G
R
Q
L
L
Y
D
Site 72
Y779
P
S
G
R
Q
L
L
Y
D
A
I
K
H
Q
K
Site 73
S787
D
A
I
K
H
Q
K
S
S
N
N
V
R
I
S
Site 74
S794
S
S
N
N
V
R
I
S
M
I
N
N
P
A
K
Site 75
S804
N
N
P
A
K
E
I
S
Y
E
N
T
Q
I
S
Site 76
T808
K
E
I
S
Y
E
N
T
Q
I
S
R
A
I
W
Site 77
S823
A
A
L
Q
T
Q
T
S
N
A
A
K
N
F
I
Site 78
S868
F
K
E
V
F
E
S
S
K
M
D
F
I
L
S
Site 79
S895
K
G
Q
R
A
V
I
S
N
G
R
I
I
G
P
Site 80
S906
I
I
G
P
L
E
D
S
E
L
F
N
Q
D
D
Site 81
S931
T
S
G
Q
K
I
K
S
H
I
Q
Q
L
R
V
Site 82
S944
R
V
E
E
D
V
A
S
D
L
V
M
K
V
D
Site 83
S955
M
K
V
D
A
L
L
S
A
Q
P
K
G
D
P
Site 84
Y966
K
G
D
P
R
I
E
Y
Q
F
F
E
D
R
H
Site 85
S974
Q
F
F
E
D
R
H
S
A
I
K
L
R
P
K
Site 86
Y986
R
P
K
E
G
E
T
Y
F
D
V
V
A
V
V
Site 87
S1026
R
V
F
M
N
C
Q
S
K
L
S
D
M
P
L
Site 88
S1029
M
N
C
Q
S
K
L
S
D
M
P
L
K
S
F
Site 89
S1035
L
S
D
M
P
L
K
S
F
Y
R
Y
V
L
E
Site 90
Y1039
P
L
K
S
F
Y
R
Y
V
L
E
P
E
I
S
Site 91
S1046
Y
V
L
E
P
E
I
S
F
T
S
D
N
S
F
Site 92
T1048
L
E
P
E
I
S
F
T
S
D
N
S
F
A
K
Site 93
S1049
E
P
E
I
S
F
T
S
D
N
S
F
A
K
G
Site 94
S1052
I
S
F
T
S
D
N
S
F
A
K
G
P
I
A
Site 95
T1071
M
P
Q
S
P
L
F
T
L
N
L
N
T
P
E
Site 96
S1079
L
N
L
N
T
P
E
S
W
M
V
E
S
V
R
Site 97
S1084
P
E
S
W
M
V
E
S
V
R
T
P
Y
D
L
Site 98
T1087
W
M
V
E
S
V
R
T
P
Y
D
L
D
N
I
Site 99
Y1089
V
E
S
V
R
T
P
Y
D
L
D
N
I
Y
L
Site 100
Y1095
P
Y
D
L
D
N
I
Y
L
E
E
V
D
S
V
Site 101
Y1119
L
L
L
E
G
H
C
Y
D
I
T
T
G
Q
P
Site 102
T1122
E
G
H
C
Y
D
I
T
T
G
Q
P
P
R
G
Site 103
T1123
G
H
C
Y
D
I
T
T
G
Q
P
P
R
G
L
Site 104
T1133
P
P
R
G
L
Q
F
T
L
G
T
S
A
N
P
Site 105
S1137
L
Q
F
T
L
G
T
S
A
N
P
V
I
V
D
Site 106
T1145
A
N
P
V
I
V
D
T
I
V
M
A
N
L
G
Site 107
S1172
L
R
L
R
K
G
R
S
E
D
I
Y
R
I
Y
Site 108
Y1176
K
G
R
S
E
D
I
Y
R
I
Y
S
H
D
G
Site 109
Y1179
S
E
D
I
Y
R
I
Y
S
H
D
G
T
D
S
Site 110
S1180
E
D
I
Y
R
I
Y
S
H
D
G
T
D
S
P
Site 111
T1184
R
I
Y
S
H
D
G
T
D
S
P
P
D
A
D
Site 112
S1186
Y
S
H
D
G
T
D
S
P
P
D
A
D
E
V
Site 113
S1222
M
V
N
E
D
L
L
S
D
G
T
S
E
N
E
Site 114
T1225
E
D
L
L
S
D
G
T
S
E
N
E
S
G
F
Site 115
S1226
D
L
L
S
D
G
T
S
E
N
E
S
G
F
W
Site 116
S1230
D
G
T
S
E
N
E
S
G
F
W
D
S
F
K
Site 117
T1245
W
G
F
T
G
Q
K
T
E
E
V
K
Q
D
K
Site 118
S1277
F
L
R
I
M
M
L
S
V
L
K
N
T
K
T
Site 119
T1282
M
L
S
V
L
K
N
T
K
T
P
V
K
F
W
Site 120
Y1294
K
F
W
F
L
K
N
Y
L
S
P
T
F
K
E
Site 121
T1298
L
K
N
Y
L
S
P
T
F
K
E
F
I
P
Y
Site 122
Y1305
T
F
K
E
F
I
P
Y
M
A
N
E
Y
N
F
Site 123
Y1314
A
N
E
Y
N
F
Q
Y
E
L
V
Q
Y
K
W
Site 124
T1383
D
G
A
P
Y
G
Y
T
P
F
C
D
S
R
R
Site 125
Y1395
S
R
R
E
M
D
G
Y
R
F
W
K
S
G
Y
Site 126
Y1402
Y
R
F
W
K
S
G
Y
W
A
S
H
L
A
G
Site 127
Y1412
S
H
L
A
G
R
K
Y
H
I
S
A
L
Y
V
Site 128
Y1418
K
Y
H
I
S
A
L
Y
V
V
D
L
K
K
F
Site 129
Y1438
G
D
R
L
R
G
Q
Y
Q
G
L
S
Q
D
P
Site 130
S1442
R
G
Q
Y
Q
G
L
S
Q
D
P
N
S
L
S
Site 131
S1447
G
L
S
Q
D
P
N
S
L
S
N
L
D
Q
D
Site 132
S1449
S
Q
D
P
N
S
L
S
N
L
D
Q
D
L
P
Site 133
T1489
A
S
K
K
R
A
K
T
I
D
L
C
N
N
P
Site 134
T1498
D
L
C
N
N
P
M
T
K
E
P
K
L
E
A
Site 135
Y1516
I
V
P
E
W
Q
D
Y
D
Q
E
I
K
Q
L
Site 136
Y1537
E
K
E
T
G
A
L
Y
K
E
K
T
K
E
P
Site 137
T1541
G
A
L
Y
K
E
K
T
K
E
P
S
R
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation