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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLA2G3
Full Name:
Group 3 secretory phospholipase A2
Alias:
GIII sPLA2; GIII-SPLA2; Group 3 secretory phospholipase A2; Group III secretory phospholipase A2; PA2G3; Phosphatidylcholine 2-acylhydrolase GIII; Phospholipase A2, group III; SPLA2III; SPLA2-III
Type:
Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Lipid Metabolism - arachidonic acid; Lipid Metabolism - alpha-linolenic acid; EC 3.1.1.4; Phospholipase; Lipid Metabolism - linoleic acid
Mass (Da):
57150
Number AA:
UniProt ID:
Q9NZ20
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0047498
PhosphoSite+
KinaseNET
Biological Process:
GO:0016042
GO:0006644
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
G
S
P
A
L
R
W
Y
R
T
S
C
H
L
T
Site 2
T29
P
A
L
R
W
Y
R
T
S
C
H
L
T
K
A
Site 3
T34
Y
R
T
S
C
H
L
T
K
A
V
P
G
N
P
Site 4
S46
G
N
P
L
G
Y
L
S
F
L
A
K
D
A
Q
Site 5
S72
H
R
R
L
Q
A
C
S
W
E
D
E
P
E
L
Site 6
T80
W
E
D
E
P
E
L
T
A
A
Y
G
A
L
C
Site 7
S95
A
H
E
T
A
W
G
S
F
I
H
T
P
G
P
Site 8
T99
A
W
G
S
F
I
H
T
P
G
P
E
L
Q
R
Site 9
S113
R
A
L
A
T
L
Q
S
Q
W
E
A
C
R
A
Site 10
S124
A
C
R
A
L
E
E
S
P
A
G
A
R
K
K
Site 11
S137
K
K
R
A
A
G
Q
S
G
V
P
G
G
G
H
Site 12
T152
Q
R
E
K
R
G
W
T
M
P
G
T
L
W
C
Site 13
S164
L
W
C
G
V
G
D
S
A
G
N
S
S
E
L
Site 14
S168
V
G
D
S
A
G
N
S
S
E
L
G
V
F
Q
Site 15
Y196
Q
N
I
S
P
L
Q
Y
N
Y
G
I
R
N
Y
Site 16
Y203
Y
N
Y
G
I
R
N
Y
R
F
H
T
I
S
H
Site 17
S227
C
L
Q
N
Q
H
D
S
I
S
D
I
V
G
V
Site 18
S229
Q
N
Q
H
D
S
I
S
D
I
V
G
V
A
F
Site 19
T277
L
A
R
L
Q
P
R
T
F
Y
N
A
S
W
S
Site 20
Y279
R
L
Q
P
R
T
F
Y
N
A
S
W
S
S
R
Site 21
S282
P
R
T
F
Y
N
A
S
W
S
S
R
A
T
S
Site 22
S284
T
F
Y
N
A
S
W
S
S
R
A
T
S
P
T
Site 23
S285
F
Y
N
A
S
W
S
S
R
A
T
S
P
T
P
Site 24
T288
A
S
W
S
S
R
A
T
S
P
T
P
S
S
R
Site 25
S289
S
W
S
S
R
A
T
S
P
T
P
S
S
R
S
Site 26
T291
S
S
R
A
T
S
P
T
P
S
S
R
S
P
A
Site 27
S293
R
A
T
S
P
T
P
S
S
R
S
P
A
P
P
Site 28
S294
A
T
S
P
T
P
S
S
R
S
P
A
P
P
K
Site 29
S296
S
P
T
P
S
S
R
S
P
A
P
P
K
P
R
Site 30
S318
G
P
P
H
Q
K
G
S
K
R
P
S
K
A
N
Site 31
S322
Q
K
G
S
K
R
P
S
K
A
N
T
T
A
L
Site 32
T326
K
R
P
S
K
A
N
T
T
A
L
Q
D
P
M
Site 33
T327
R
P
S
K
A
N
T
T
A
L
Q
D
P
M
V
Site 34
S335
A
L
Q
D
P
M
V
S
P
R
L
D
V
A
P
Site 35
S387
I
E
F
Q
L
L
N
S
A
Q
E
P
L
F
H
Site 36
S409
A
R
F
L
R
L
H
S
P
P
E
V
T
N
M
Site 37
S450
D
P
R
A
I
R
V
S
A
R
H
L
R
R
L
Site 38
T469
H
Q
L
Q
D
K
G
T
D
E
R
Q
P
W
P
Site 39
S477
D
E
R
Q
P
W
P
S
E
P
L
R
G
P
M
Site 40
S485
E
P
L
R
G
P
M
S
F
Y
N
Q
C
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation