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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLIC5
Full Name:
Chloride intracellular channel protein 5
Alias:
Chloride intracellular channel 5; FLJ90663; MST130; MSTP130; P64
Type:
Mass (Da):
46503
Number AA:
410
UniProt ID:
Q9NZA1
International Prot ID:
Isoform2 - IPI00027193
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0015629
GO:0005938
Uniprot
OncoNet
Molecular Function:
GO:0031404
GO:0005515
GO:0005247
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0007565
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
D
E
D
Y
S
T
I
Y
D
T
I
Q
N
E
R
Site 2
T12
D
Y
S
T
I
Y
D
T
I
Q
N
E
R
T
Y
Site 3
Y19
T
I
Q
N
E
R
T
Y
E
V
P
D
Q
P
E
Site 4
S30
D
Q
P
E
E
N
E
S
P
H
Y
D
D
V
H
Site 5
Y33
E
E
N
E
S
P
H
Y
D
D
V
H
E
Y
L
Site 6
Y39
H
Y
D
D
V
H
E
Y
L
R
P
E
N
D
L
Site 7
Y47
L
R
P
E
N
D
L
Y
A
T
Q
L
N
T
H
Site 8
Y56
T
Q
L
N
T
H
E
Y
D
F
V
S
V
Y
T
Site 9
Y62
E
Y
D
F
V
S
V
Y
T
I
K
G
E
E
T
Site 10
S70
T
I
K
G
E
E
T
S
L
A
S
V
Q
S
E
Site 11
S73
G
E
E
T
S
L
A
S
V
Q
S
E
D
R
G
Site 12
S76
T
S
L
A
S
V
Q
S
E
D
R
G
Y
L
L
Site 13
Y81
V
Q
S
E
D
R
G
Y
L
L
P
D
E
I
Y
Site 14
Y88
Y
L
L
P
D
E
I
Y
S
E
L
Q
E
A
H
Site 15
S106
P
Q
E
D
R
G
I
S
M
E
G
L
Y
S
S
Site 16
Y111
G
I
S
M
E
G
L
Y
S
S
T
Q
D
Q
Q
Site 17
S112
I
S
M
E
G
L
Y
S
S
T
Q
D
Q
Q
L
Site 18
S113
S
M
E
G
L
Y
S
S
T
Q
D
Q
Q
L
C
Site 19
S129
A
E
L
Q
E
N
G
S
V
M
K
E
D
L
P
Site 20
S137
V
M
K
E
D
L
P
S
P
S
S
F
T
I
Q
Site 21
S139
K
E
D
L
P
S
P
S
S
F
T
I
Q
H
S
Site 22
S140
E
D
L
P
S
P
S
S
F
T
I
Q
H
S
K
Site 23
S146
S
S
F
T
I
Q
H
S
K
A
F
S
T
T
K
Site 24
T151
Q
H
S
K
A
F
S
T
T
K
Y
S
C
Y
S
Site 25
Y154
K
A
F
S
T
T
K
Y
S
C
Y
S
D
A
E
Site 26
S155
A
F
S
T
T
K
Y
S
C
Y
S
D
A
E
G
Site 27
Y157
S
T
T
K
Y
S
C
Y
S
D
A
E
G
L
E
Site 28
S158
T
T
K
Y
S
C
Y
S
D
A
E
G
L
E
E
Site 29
T235
G
T
H
P
P
F
L
T
F
N
G
D
V
K
T
Site 30
T242
T
F
N
G
D
V
K
T
D
V
N
K
I
E
E
Site 31
T254
I
E
E
F
L
E
E
T
L
T
P
E
K
Y
P
Site 32
T256
E
F
L
E
E
T
L
T
P
E
K
Y
P
K
L
Site 33
Y260
E
T
L
T
P
E
K
Y
P
K
L
A
A
K
H
Site 34
S270
L
A
A
K
H
R
E
S
N
T
A
G
I
D
I
Site 35
T272
A
K
H
R
E
S
N
T
A
G
I
D
I
F
S
Site 36
T301
A
A
L
E
R
G
L
T
K
A
L
K
K
L
D
Site 37
Y310
A
L
K
K
L
D
D
Y
L
N
T
P
L
P
E
Site 38
T313
K
L
D
D
Y
L
N
T
P
L
P
E
E
I
D
Site 39
S330
T
C
G
E
D
K
G
S
R
R
K
F
L
D
G
Site 40
Y364
V
A
K
K
Y
R
N
Y
D
I
P
A
E
M
T
Site 41
Y376
E
M
T
G
L
W
R
Y
L
K
N
A
Y
A
R
Site 42
Y381
W
R
Y
L
K
N
A
Y
A
R
D
E
F
T
N
Site 43
T389
A
R
D
E
F
T
N
T
C
A
A
D
S
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation