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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM120A
Full Name:
Constitutive coactivator of PPAR-gamma-like protein 1
Alias:
C9orf10; CI010; F120A; Family with sequence similarity 120A; KIAA0183; Oxidative stress-associated Src activator; Protein FAM120A
Type:
Unknown function
Mass (Da):
121888
Number AA:
1118
UniProt ID:
Q9NZB2
International Prot ID:
IPI00472054
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
G
V
Q
G
F
Q
D
Y
I
E
K
H
C
P
S
Site 2
S30
L
Q
K
L
A
R
G
S
L
V
G
G
G
R
Q
Site 3
T42
G
R
Q
R
P
P
Q
T
P
L
R
L
L
V
D
Site 4
Y62
H
R
L
Y
G
G
F
Y
T
D
W
V
S
G
G
Site 5
T118
R
Q
G
N
E
R
Q
T
A
Q
Q
I
V
S
H
Site 6
S124
Q
T
A
Q
Q
I
V
S
H
V
Q
N
K
G
T
Site 7
T131
S
H
V
Q
N
K
G
T
P
P
P
K
V
W
F
Site 8
S206
S
A
H
A
L
K
L
S
R
N
G
K
S
L
T
Site 9
S211
K
L
S
R
N
G
K
S
L
T
T
S
Q
Y
L
Site 10
T213
S
R
N
G
K
S
L
T
T
S
Q
Y
L
M
H
Site 11
S215
N
G
K
S
L
T
T
S
Q
Y
L
M
H
E
V
Site 12
Y217
K
S
L
T
T
S
Q
Y
L
M
H
E
V
A
K
Site 13
S252
L
P
D
E
D
L
A
S
F
H
W
S
L
L
G
Site 14
S256
D
L
A
S
F
H
W
S
L
L
G
P
E
H
P
Site 15
S266
G
P
E
H
P
L
A
S
L
K
V
R
A
H
Q
Site 16
T296
Y
V
R
N
I
Q
D
T
S
D
L
D
A
I
A
Site 17
S310
A
K
D
V
F
Q
H
S
Q
S
R
T
D
D
K
Site 18
T314
F
Q
H
S
Q
S
R
T
D
D
K
V
I
R
F
Site 19
Y327
R
F
K
R
A
I
G
Y
Y
S
A
T
S
K
P
Site 20
Y328
F
K
R
A
I
G
Y
Y
S
A
T
S
K
P
M
Site 21
S329
K
R
A
I
G
Y
Y
S
A
T
S
K
P
M
S
Site 22
T331
A
I
G
Y
Y
S
A
T
S
K
P
M
S
F
H
Site 23
S332
I
G
Y
Y
S
A
T
S
K
P
M
S
F
H
P
Site 24
S336
S
A
T
S
K
P
M
S
F
H
P
P
H
Y
L
Site 25
Y342
M
S
F
H
P
P
H
Y
L
A
A
R
P
G
P
Site 26
S383
P
V
A
P
Q
V
P
S
P
G
G
A
P
G
Q
Site 27
Y393
G
A
P
G
Q
G
P
Y
P
Y
S
L
S
E
P
Site 28
Y395
P
G
Q
G
P
Y
P
Y
S
L
S
E
P
A
P
Site 29
S396
G
Q
G
P
Y
P
Y
S
L
S
E
P
A
P
L
Site 30
S398
G
P
Y
P
Y
S
L
S
E
P
A
P
L
T
L
Site 31
T404
L
S
E
P
A
P
L
T
L
D
T
S
G
K
N
Site 32
S408
A
P
L
T
L
D
T
S
G
K
N
L
T
E
Q
Site 33
T413
D
T
S
G
K
N
L
T
E
Q
N
S
Y
S
N
Site 34
S417
K
N
L
T
E
Q
N
S
Y
S
N
I
P
H
E
Site 35
Y418
N
L
T
E
Q
N
S
Y
S
N
I
P
H
E
G
Site 36
S419
L
T
E
Q
N
S
Y
S
N
I
P
H
E
G
K
Site 37
T428
I
P
H
E
G
K
H
T
P
L
Y
E
R
S
S
Site 38
Y431
E
G
K
H
T
P
L
Y
E
R
S
S
P
I
N
Site 39
S434
H
T
P
L
Y
E
R
S
S
P
I
N
P
A
Q
Site 40
S435
T
P
L
Y
E
R
S
S
P
I
N
P
A
Q
S
Site 41
S442
S
P
I
N
P
A
Q
S
G
S
P
N
H
V
D
Site 42
S444
I
N
P
A
Q
S
G
S
P
N
H
V
D
S
A
Site 43
S450
G
S
P
N
H
V
D
S
A
Y
F
P
G
S
S
Site 44
Y452
P
N
H
V
D
S
A
Y
F
P
G
S
S
T
S
Site 45
S456
D
S
A
Y
F
P
G
S
S
T
S
S
S
S
D
Site 46
S457
S
A
Y
F
P
G
S
S
T
S
S
S
S
D
N
Site 47
T458
A
Y
F
P
G
S
S
T
S
S
S
S
D
N
D
Site 48
S460
F
P
G
S
S
T
S
S
S
S
D
N
D
E
G
Site 49
S461
P
G
S
S
T
S
S
S
S
D
N
D
E
G
S
Site 50
S462
G
S
S
T
S
S
S
S
D
N
D
E
G
S
G
Site 51
S468
S
S
D
N
D
E
G
S
G
G
A
T
N
H
I
Site 52
T472
D
E
G
S
G
G
A
T
N
H
I
S
G
N
K
Site 53
T485
N
K
I
G
W
E
K
T
G
S
H
S
E
P
Q
Site 54
S487
I
G
W
E
K
T
G
S
H
S
E
P
Q
A
R
Site 55
T501
R
G
D
P
G
D
Q
T
K
A
E
G
S
S
T
Site 56
S506
D
Q
T
K
A
E
G
S
S
T
A
S
S
G
S
Site 57
S507
Q
T
K
A
E
G
S
S
T
A
S
S
G
S
Q
Site 58
T508
T
K
A
E
G
S
S
T
A
S
S
G
S
Q
L
Site 59
S510
A
E
G
S
S
T
A
S
S
G
S
Q
L
A
E
Site 60
S511
E
G
S
S
T
A
S
S
G
S
Q
L
A
E
G
Site 61
S513
S
S
T
A
S
S
G
S
Q
L
A
E
G
K
G
Site 62
S521
Q
L
A
E
G
K
G
S
Q
M
G
T
V
Q
P
Site 63
T525
G
K
G
S
Q
M
G
T
V
Q
P
I
P
C
L
Site 64
T544
T
R
N
H
M
D
I
T
T
P
P
L
P
P
V
Site 65
T545
R
N
H
M
D
I
T
T
P
P
L
P
P
V
A
Site 66
Y569
R
H
K
K
G
L
M
Y
P
Y
I
F
H
V
L
Site 67
S586
G
E
I
K
I
A
V
S
I
E
D
E
A
N
K
Site 68
S615
Y
V
Y
G
V
L
F
S
L
A
E
S
R
K
K
Site 69
S619
V
L
F
S
L
A
E
S
R
K
K
T
E
R
L
Site 70
T623
L
A
E
S
R
K
K
T
E
R
L
A
F
R
K
Site 71
S638
N
R
L
P
P
E
F
S
P
V
I
I
K
E
W
Site 72
Y648
I
I
K
E
W
A
A
Y
K
G
K
S
P
Q
T
Site 73
S652
W
A
A
Y
K
G
K
S
P
Q
T
P
E
L
V
Site 74
T655
Y
K
G
K
S
P
Q
T
P
E
L
V
E
A
L
Site 75
T668
A
L
A
F
R
E
W
T
C
P
N
L
K
R
L
Site 76
Y721
V
L
C
C
V
L
R
Y
M
V
Q
W
P
G
A
Site 77
S745
A
F
L
A
Q
A
L
S
P
K
L
Y
E
P
D
Site 78
Y749
Q
A
L
S
P
K
L
Y
E
P
D
Q
L
Q
E
Site 79
S809
F
D
G
K
L
F
Q
S
K
L
L
K
A
S
R
Site 80
S815
Q
S
K
L
L
K
A
S
R
E
K
T
P
L
I
Site 81
T819
L
K
A
S
R
E
K
T
P
L
I
D
L
C
D
Site 82
S841
K
V
E
K
M
R
Q
S
V
L
E
G
L
S
F
Site 83
S847
Q
S
V
L
E
G
L
S
F
S
R
Q
S
H
T
Site 84
S849
V
L
E
G
L
S
F
S
R
Q
S
H
T
L
P
Site 85
S852
G
L
S
F
S
R
Q
S
H
T
L
P
F
P
P
Site 86
T854
S
F
S
R
Q
S
H
T
L
P
F
P
P
P
P
Site 87
Y866
P
P
P
A
L
P
F
Y
P
A
S
A
Y
P
R
Site 88
S869
A
L
P
F
Y
P
A
S
A
Y
P
R
H
F
G
Site 89
Y871
P
F
Y
P
A
S
A
Y
P
R
H
F
G
P
V
Site 90
S881
H
F
G
P
V
P
P
S
Q
G
R
G
R
G
F
Site 91
Y898
V
C
G
F
G
G
P
Y
G
E
T
V
A
T
G
Site 92
T901
F
G
G
P
Y
G
E
T
V
A
T
G
P
Y
R
Site 93
T904
P
Y
G
E
T
V
A
T
G
P
Y
R
A
F
R
Site 94
Y907
E
T
V
A
T
G
P
Y
R
A
F
R
V
A
A
Site 95
S923
S
G
H
C
G
A
F
S
G
S
D
S
S
R
T
Site 96
S925
H
C
G
A
F
S
G
S
D
S
S
R
T
S
K
Site 97
S927
G
A
F
S
G
S
D
S
S
R
T
S
K
S
Q
Site 98
S928
A
F
S
G
S
D
S
S
R
T
S
K
S
Q
G
Site 99
T930
S
G
S
D
S
S
R
T
S
K
S
Q
G
G
V
Site 100
S931
G
S
D
S
S
R
T
S
K
S
Q
G
G
V
Q
Site 101
S933
D
S
S
R
T
S
K
S
Q
G
G
V
Q
P
I
Site 102
S942
G
G
V
Q
P
I
P
S
Q
G
G
K
L
E
I
Site 103
S960
V
V
G
H
W
A
G
S
R
R
G
R
G
G
R
Site 104
T991
R
P
R
G
V
I
S
T
P
V
I
R
T
F
G
Site 105
T996
I
S
T
P
V
I
R
T
F
G
R
G
G
R
Y
Site 106
Y1003
T
F
G
R
G
G
R
Y
Y
G
R
G
Y
K
N
Site 107
Y1004
F
G
R
G
G
R
Y
Y
G
R
G
Y
K
N
Q
Site 108
Y1008
G
R
Y
Y
G
R
G
Y
K
N
Q
A
A
I
Q
Site 109
Y1020
A
I
Q
G
R
P
P
Y
A
A
S
A
E
E
V
Site 110
S1023
G
R
P
P
Y
A
A
S
A
E
E
V
A
K
E
Site 111
S1033
E
V
A
K
E
L
K
S
K
S
G
E
S
K
S
Site 112
S1035
A
K
E
L
K
S
K
S
G
E
S
K
S
S
A
Site 113
S1038
L
K
S
K
S
G
E
S
K
S
S
A
M
S
S
Site 114
S1040
S
K
S
G
E
S
K
S
S
A
M
S
S
D
G
Site 115
S1041
K
S
G
E
S
K
S
S
A
M
S
S
D
G
S
Site 116
S1044
E
S
K
S
S
A
M
S
S
D
G
S
L
A
E
Site 117
S1045
S
K
S
S
A
M
S
S
D
G
S
L
A
E
N
Site 118
S1048
S
A
M
S
S
D
G
S
L
A
E
N
G
V
M
Site 119
S1075
T
G
D
A
R
A
P
S
H
S
E
S
A
L
N
Site 120
S1077
D
A
R
A
P
S
H
S
E
S
A
L
N
N
D
Site 121
S1079
R
A
P
S
H
S
E
S
A
L
N
N
D
S
K
Site 122
S1085
E
S
A
L
N
N
D
S
K
T
C
N
T
N
P
Site 123
T1087
A
L
N
N
D
S
K
T
C
N
T
N
P
H
L
Site 124
S1098
N
P
H
L
N
A
L
S
T
D
S
A
C
R
R
Site 125
T1099
P
H
L
N
A
L
S
T
D
S
A
C
R
R
E
Site 126
S1101
L
N
A
L
S
T
D
S
A
C
R
R
E
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation