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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMARCAL1
Full Name:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Alias:
EC 3.6.1.-; HARP; HepA-related protein; HHARP; SMAL1; Sucrose nonfermenting protein 2-like 1
Type:
Helicase
Mass (Da):
105938
Number AA:
954
UniProt ID:
Q9NZC9
International Prot ID:
IPI00386311
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006325
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
S
L
P
L
T
E
E
Q
R
K
K
I
Site 2
S37
A
E
Q
H
Q
R
T
S
S
G
T
S
I
A
G
Site 3
S38
E
Q
H
Q
R
T
S
S
G
T
S
I
A
G
N
Site 4
S41
Q
R
T
S
S
G
T
S
I
A
G
N
P
F
Q
Site 5
S61
S
Q
N
F
P
R
E
S
C
K
P
V
S
H
G
Site 6
S66
R
E
S
C
K
P
V
S
H
G
V
I
F
K
Q
Site 7
S77
I
F
K
Q
Q
N
L
S
S
S
S
N
A
D
Q
Site 8
S91
Q
R
P
H
D
S
H
S
F
Q
A
K
G
I
W
Site 9
T106
K
K
P
E
E
M
P
T
A
C
P
G
H
S
P
Site 10
S112
P
T
A
C
P
G
H
S
P
R
S
Q
M
A
L
Site 11
S115
C
P
G
H
S
P
R
S
Q
M
A
L
T
G
I
Site 12
T120
P
R
S
Q
M
A
L
T
G
I
S
P
P
L
A
Site 13
S129
I
S
P
P
L
A
Q
S
P
P
E
V
P
K
Q
Site 14
S140
V
P
K
Q
Q
L
L
S
Y
E
L
G
Q
G
H
Site 15
Y141
P
K
Q
Q
L
L
S
Y
E
L
G
Q
G
H
A
Site 16
S151
G
Q
G
H
A
Q
A
S
P
E
I
R
F
T
P
Site 17
T157
A
S
P
E
I
R
F
T
P
F
A
N
P
T
H
Site 18
S172
K
P
L
A
K
P
K
S
S
Q
E
T
P
A
H
Site 19
S173
P
L
A
K
P
K
S
S
Q
E
T
P
A
H
S
Site 20
T176
K
P
K
S
S
Q
E
T
P
A
H
S
S
G
Q
Site 21
S181
Q
E
T
P
A
H
S
S
G
Q
P
P
R
D
A
Site 22
T194
D
A
K
L
E
A
K
T
A
K
A
S
P
S
G
Site 23
S198
E
A
K
T
A
K
A
S
P
S
G
Q
N
I
S
Site 24
S205
S
P
S
G
Q
N
I
S
Y
I
H
S
S
S
E
Site 25
Y206
P
S
G
Q
N
I
S
Y
I
H
S
S
S
E
S
Site 26
S209
Q
N
I
S
Y
I
H
S
S
S
E
S
V
T
P
Site 27
S211
I
S
Y
I
H
S
S
S
E
S
V
T
P
R
T
Site 28
S213
Y
I
H
S
S
S
E
S
V
T
P
R
T
E
G
Site 29
T215
H
S
S
S
E
S
V
T
P
R
T
E
G
R
L
Site 30
T218
S
E
S
V
T
P
R
T
E
G
R
L
Q
Q
K
Site 31
S226
E
G
R
L
Q
Q
K
S
G
S
S
V
Q
K
G
Site 32
S228
R
L
Q
Q
K
S
G
S
S
V
Q
K
G
V
N
Site 33
S236
S
V
Q
K
G
V
N
S
Q
K
G
K
C
V
R
Site 34
T264
E
L
I
A
V
F
K
T
L
P
S
K
N
Y
D
Site 35
Y284
W
N
F
S
M
N
D
Y
S
A
L
M
K
A
A
Site 36
T296
K
A
A
Q
S
L
P
T
V
N
L
Q
P
L
E
Site 37
Y306
L
Q
P
L
E
W
A
Y
G
S
S
E
S
P
S
Site 38
S308
P
L
E
W
A
Y
G
S
S
E
S
P
S
T
S
Site 39
S309
L
E
W
A
Y
G
S
S
E
S
P
S
T
S
S
Site 40
S311
W
A
Y
G
S
S
E
S
P
S
T
S
S
E
G
Site 41
S313
Y
G
S
S
E
S
P
S
T
S
S
E
G
Q
A
Site 42
T314
G
S
S
E
S
P
S
T
S
S
E
G
Q
A
G
Site 43
S315
S
S
E
S
P
S
T
S
S
E
G
Q
A
G
L
Site 44
S316
S
E
S
P
S
T
S
S
E
G
Q
A
G
L
P
Site 45
S339
K
G
R
C
M
L
I
S
R
A
Y
F
E
A
D
Site 46
S362
A
L
F
K
Q
M
D
S
R
R
Y
D
V
K
T
Site 47
Y365
K
Q
M
D
S
R
R
Y
D
V
K
T
R
K
W
Site 48
T369
S
R
R
Y
D
V
K
T
R
K
W
S
F
L
L
Site 49
S373
D
V
K
T
R
K
W
S
F
L
L
E
E
H
S
Site 50
S380
S
F
L
L
E
E
H
S
K
L
I
A
K
V
R
Site 51
S413
A
S
Q
L
K
K
T
S
L
S
L
T
P
D
V
Site 52
S415
Q
L
K
K
T
S
L
S
L
T
P
D
V
P
E
Site 53
T417
K
K
T
S
L
S
L
T
P
D
V
P
E
A
D
Site 54
S426
D
V
P
E
A
D
L
S
E
V
D
P
K
L
V
Site 55
T492
V
P
S
S
V
R
F
T
W
E
Q
A
F
L
R
Site 56
S528
A
G
L
I
N
I
V
S
F
D
L
L
S
K
L
Site 57
S533
I
V
S
F
D
L
L
S
K
L
E
K
Q
L
K
Site 58
T541
K
L
E
K
Q
L
K
T
P
F
K
V
V
I
I
Site 59
S551
K
V
V
I
I
D
E
S
H
F
L
K
N
S
R
Site 60
S557
E
S
H
F
L
K
N
S
R
T
A
R
C
R
A
Site 61
T559
H
F
L
K
N
S
R
T
A
R
C
R
A
A
M
Site 62
S585
L
S
G
T
P
A
M
S
R
P
A
E
L
Y
T
Site 63
Y624
R
M
P
W
G
W
D
Y
S
G
S
S
N
L
G
Site 64
S627
W
G
W
D
Y
S
G
S
S
N
L
G
E
L
K
Site 65
S652
R
L
K
S
D
V
L
S
Q
L
P
A
K
Q
R
Site 66
T673
P
G
R
I
N
A
R
T
R
A
A
L
D
A
A
Site 67
T690
E
M
T
T
K
D
K
T
K
Q
Q
Q
K
D
A
Site 68
S758
Q
H
I
R
I
D
G
S
T
S
S
A
E
R
E
Site 69
T759
H
I
R
I
D
G
S
T
S
S
A
E
R
E
D
Site 70
S761
R
I
D
G
S
T
S
S
A
E
R
E
D
L
C
Site 71
S783
R
H
A
V
A
V
L
S
I
T
A
A
N
M
G
Site 72
T824
R
V
H
R
I
G
Q
T
S
S
V
G
I
H
Y
Site 73
Y841
A
K
G
T
A
D
D
Y
L
W
P
L
I
Q
E
Site 74
S864
G
L
S
E
T
N
F
S
E
M
T
E
S
T
D
Site 75
T867
E
T
N
F
S
E
M
T
E
S
T
D
Y
L
Y
Site 76
S869
N
F
S
E
M
T
E
S
T
D
Y
L
Y
K
D
Site 77
Y872
E
M
T
E
S
T
D
Y
L
Y
K
D
P
K
Q
Site 78
Y874
T
E
S
T
D
Y
L
Y
K
D
P
K
Q
Q
K
Site 79
S889
I
Y
D
L
F
Q
K
S
F
E
K
E
G
S
D
Site 80
S895
K
S
F
E
K
E
G
S
D
M
E
L
L
E
A
Site 81
S905
E
L
L
E
A
A
E
S
F
D
P
G
S
A
S
Site 82
S910
A
E
S
F
D
P
G
S
A
S
G
T
S
G
S
Site 83
S912
S
F
D
P
G
S
A
S
G
T
S
G
S
S
S
Site 84
T914
D
P
G
S
A
S
G
T
S
G
S
S
S
Q
N
Site 85
S915
P
G
S
A
S
G
T
S
G
S
S
S
Q
N
M
Site 86
S917
S
A
S
G
T
S
G
S
S
S
Q
N
M
G
D
Site 87
S919
S
G
T
S
G
S
S
S
Q
N
M
G
D
T
L
Site 88
T925
S
S
Q
N
M
G
D
T
L
D
E
S
S
L
T
Site 89
S929
M
G
D
T
L
D
E
S
S
L
T
A
S
P
Q
Site 90
S930
G
D
T
L
D
E
S
S
L
T
A
S
P
Q
K
Site 91
T932
T
L
D
E
S
S
L
T
A
S
P
Q
K
K
R
Site 92
S934
D
E
S
S
L
T
A
S
P
Q
K
K
R
R
F
Site 93
S952
D
N
W
D
S
F
T
S
P
L
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation