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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPG21
Full Name:
Maspardin
Alias:
Maspardin: Spastic paraplegia 21 autosomal recessive Mast syndrome protein: Acid cluster protein 33
Type:
Mass (Da):
34942
Number AA:
308
UniProt ID:
Q9NZD8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005768
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0042609
PhosphoSite+
KinaseNET
Biological Process:
GO:0050851
GO:0008219
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
E
I
K
V
S
P
D
Y
N
W
F
R
G
T
V
Site 2
S33
D
D
D
S
K
I
W
S
L
Y
D
A
G
P
R
Site 3
Y35
D
S
K
I
W
S
L
Y
D
A
G
P
R
S
I
Site 4
Y121
L
A
Q
K
F
A
E
Y
T
H
K
S
P
R
V
Site 5
S125
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Site 6
S130
H
K
S
P
R
V
H
S
L
I
L
C
N
S
F
Site 7
S190
F
M
V
D
R
L
E
S
L
G
Q
S
E
L
A
Site 8
S194
R
L
E
S
L
G
Q
S
E
L
A
S
R
L
T
Site 9
S198
L
G
Q
S
E
L
A
S
R
L
T
L
N
C
Q
Site 10
T201
S
E
L
A
S
R
L
T
L
N
C
Q
N
S
Y
Site 11
Y208
T
L
N
C
Q
N
S
Y
V
E
P
H
K
I
R
Site 12
S228
I
M
D
V
F
D
Q
S
A
L
S
T
E
A
K
Site 13
S231
V
F
D
Q
S
A
L
S
T
E
A
K
E
E
M
Site 14
T232
F
D
Q
S
A
L
S
T
E
A
K
E
E
M
Y
Site 15
Y242
K
E
E
M
Y
K
L
Y
P
N
A
R
R
A
H
Site 16
T252
A
R
R
A
H
L
K
T
G
G
N
F
P
Y
L
Site 17
Y258
K
T
G
G
N
F
P
Y
L
C
R
S
A
E
V
Site 18
Y281
L
Q
F
H
G
T
K
Y
A
A
I
D
P
S
M
Site 19
S287
K
Y
A
A
I
D
P
S
M
V
S
A
E
E
L
Site 20
S300
E
L
E
V
Q
K
G
S
L
G
I
S
Q
E
E
Site 21
S304
Q
K
G
S
L
G
I
S
Q
E
E
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation