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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GRHL1
Full Name:
Grainyhead-like protein 1 homolog
Alias:
Grainyhead-like 1; Grainyhead-like protein 1; LBP 32; LBP32; LBP-32; MGR; NH32; TFCP2L2; Transcription factor CP2-like 2
Type:
Transcription factor
Mass (Da):
70113
Number AA:
618
UniProt ID:
Q9NZI5
International Prot ID:
IPI00181670
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
V
L
Q
N
E
A
L
Y
P
Q
R
R
S
Y
T
Site 2
S25
A
L
Y
P
Q
R
R
S
Y
T
S
E
D
E
A
Site 3
Y26
L
Y
P
Q
R
R
S
Y
T
S
E
D
E
A
W
Site 4
T27
Y
P
Q
R
R
S
Y
T
S
E
D
E
A
W
K
Site 5
S28
P
Q
R
R
S
Y
T
S
E
D
E
A
W
K
S
Site 6
S35
S
E
D
E
A
W
K
S
F
L
E
N
P
L
T
Site 7
Y65
A
A
A
L
G
L
L
Y
D
Y
Y
K
V
P
R
Site 8
Y67
A
L
G
L
L
Y
D
Y
Y
K
V
P
R
E
R
Site 9
Y68
L
G
L
L
Y
D
Y
Y
K
V
P
R
E
R
R
Site 10
S76
K
V
P
R
E
R
R
S
S
T
A
K
P
E
V
Site 11
S77
V
P
R
E
R
R
S
S
T
A
K
P
E
V
E
Site 12
T78
P
R
E
R
R
S
S
T
A
K
P
E
V
E
H
Site 13
S91
E
H
P
E
P
D
H
S
K
R
N
S
I
P
I
Site 14
S95
P
D
H
S
K
R
N
S
I
P
I
V
T
E
Q
Site 15
Y175
V
G
I
P
P
A
V
Y
H
P
E
P
T
E
R
Site 16
T180
A
V
Y
H
P
E
P
T
E
R
V
V
V
F
D
Site 17
T192
V
F
D
R
N
L
N
T
D
Q
F
S
S
G
A
Site 18
T208
A
P
N
A
Q
R
R
T
P
D
S
T
F
S
E
Site 19
S211
A
Q
R
R
T
P
D
S
T
F
S
E
T
F
K
Site 20
T212
Q
R
R
T
P
D
S
T
F
S
E
T
F
K
E
Site 21
S214
R
T
P
D
S
T
F
S
E
T
F
K
E
G
V
Site 22
T216
P
D
S
T
F
S
E
T
F
K
E
G
V
Q
E
Site 23
Y242
P
G
M
N
S
E
D
Y
V
F
D
S
V
S
G
Site 24
S246
S
E
D
Y
V
F
D
S
V
S
G
N
N
F
E
Site 25
T255
S
G
N
N
F
E
Y
T
L
E
A
S
K
S
L
Site 26
S261
Y
T
L
E
A
S
K
S
L
R
Q
K
P
G
D
Site 27
Y273
P
G
D
S
T
M
T
Y
L
N
K
G
Q
F
Y
Site 28
T283
K
G
Q
F
Y
P
I
T
L
K
E
V
S
S
S
Site 29
S288
P
I
T
L
K
E
V
S
S
S
E
G
I
H
H
Site 30
S289
I
T
L
K
E
V
S
S
S
E
G
I
H
H
P
Site 31
S290
T
L
K
E
V
S
S
S
E
G
I
H
H
P
I
Site 32
S298
E
G
I
H
H
P
I
S
K
V
R
S
V
I
M
Site 33
S313
V
V
F
A
E
D
K
S
R
E
D
Q
L
R
H
Site 34
T330
Y
W
H
S
R
Q
H
T
A
K
Q
R
C
I
D
Site 35
Y341
R
C
I
D
I
A
D
Y
K
E
S
F
N
T
I
Site 36
T347
D
Y
K
E
S
F
N
T
I
S
N
I
E
E
I
Site 37
S349
K
E
S
F
N
T
I
S
N
I
E
E
I
A
Y
Site 38
Y356
S
N
I
E
E
I
A
Y
N
A
I
S
F
T
W
Site 39
S379
F
I
S
V
N
C
L
S
T
D
F
S
S
Q
K
Site 40
T380
I
S
V
N
C
L
S
T
D
F
S
S
Q
K
G
Site 41
S383
N
C
L
S
T
D
F
S
S
Q
K
G
V
K
G
Site 42
S384
C
L
S
T
D
F
S
S
Q
K
G
V
K
G
L
Site 43
T399
P
L
N
I
Q
V
D
T
Y
S
Y
N
N
R
S
Site 44
Y400
L
N
I
Q
V
D
T
Y
S
Y
N
N
R
S
N
Site 45
Y402
I
Q
V
D
T
Y
S
Y
N
N
R
S
N
K
P
Site 46
Y414
N
K
P
V
H
R
A
Y
C
Q
I
K
V
F
C
Site 47
S437
R
D
E
E
R
K
Q
S
K
R
K
V
S
D
V
Site 48
S442
K
Q
S
K
R
K
V
S
D
V
K
V
P
L
L
Site 49
S451
V
K
V
P
L
L
P
S
H
K
R
M
D
I
T
Site 50
T458
S
H
K
R
M
D
I
T
V
F
K
P
F
I
D
Site 51
S501
E
E
L
E
G
E
G
S
V
L
K
R
G
P
Y
Site 52
Y508
S
V
L
K
R
G
P
Y
G
T
E
D
D
F
A
Site 53
T510
L
K
R
G
P
Y
G
T
E
D
D
F
A
V
P
Site 54
S519
D
D
F
A
V
P
P
S
T
K
L
A
R
I
E
Site 55
Y534
E
P
K
R
V
L
L
Y
V
R
K
E
S
E
E
Site 56
S539
L
L
Y
V
R
K
E
S
E
E
V
F
D
A
L
Site 57
S561
K
G
L
M
E
A
I
S
D
K
Y
D
V
P
H
Site 58
Y564
M
E
A
I
S
D
K
Y
D
V
P
H
D
K
I
Site 59
Y594
D
D
N
I
V
K
H
Y
S
N
E
D
T
F
Q
Site 60
T599
K
H
Y
S
N
E
D
T
F
Q
L
Q
I
E
E
Site 61
S610
Q
I
E
E
A
G
G
S
Y
K
L
T
L
T
E
Site 62
Y611
I
E
E
A
G
G
S
Y
K
L
T
L
T
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation