PhosphoNET

           
Protein Info 
   
Short Name:  NUDT4
Full Name:  Diphosphoinositol polyphosphate phosphohydrolase 2
Alias:  DIPP2; KIAA0487
Type:  Enzyme - Hydrolase
Mass (Da):  20306
Number AA:  180
UniProt ID:  Q9NZJ9
International Prot ID:  IPI00607685
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0008486  GO:0000287  GO:0030145 PhosphoSite+ KinaseNET
Biological Process:  GO:0019722  GO:0009187  GO:0019935 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T11FKPNQTRTYDREGFK
Site 2Y12KPNQTRTYDREGFKK
Site 3S38EDEVLLVSSSRYPDQ
Site 4S39DEVLLVSSSRYPDQW
Site 5S40EVLLVSSSRYPDQWI
Site 6Y42LLVSSSRYPDQWIVP
Site 7Y68GAAVREVYEEAGVKG
Site 8Y94QDRKHRTYVYVLTVT
Site 9Y96RKHRTYVYVLTVTEI
Site 10S110ILEDWEDSVNIGRKR
Site 11Y139HKPVHAEYLEKLKLG
Site 12S148EKLKLGCSPANGNST
Site 13S154CSPANGNSTVPSLPD
Site 14T155SPANGNSTVPSLPDN
Site 15S158NGNSTVPSLPDNNAL
Site 16S177AQTSGLPSSVR____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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