PhosphoNET

           
Protein Info 
   
Short Name:  ITSN2
Full Name:  Intersectin-2
Alias:  EH and SH3 domains protein 2; EH domain and SH3 domain regulator of endocytosis 2; ESE2; Intersectin 2; ITN2; KIAA1256; PRO2015; SH3 domain protein 1B; SH3 domain-containing protein 1B; SH3D1B; SH3P18; SH3P18-like WASP associated protein; SH3P18-like WASP-associated protein; SWA; SWAP
Type:  Adapter/scaffold protein
Mass (Da):  193461
Number AA:  1697
UniProt ID:  Q9NZM3
International Prot ID:  IPI00216423
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0005089  GO:0005070  GO:0005509 PhosphoSite+ KinaseNET
Biological Process:  GO:0006897  GO:0035023   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S165VPSVSTSSLPNGTAS
Site 2S183PLPIPYSSSTLPHGS
Site 3S184LPIPYSSSTLPHGSS
Site 4S191STLPHGSSYSLMMGG
Site 5S216SLIDLGSSSSTSSTA
Site 6S217LIDLGSSSSTSSTAS
Site 7S218IDLGSSSSTSSTASL
Site 8S221GSSSSTSSTASLSGN
Site 9S818YVEKMPSSENEKAVS
Site 10S844LSATSTSSEPLSSNQ
Site 11S849TSSEPLSSNQPASVT
Site 12S1118VKLLGPSSERATPAF
Site 13S1376ESHADHSSLKLALER
Site 14S1471VKQFAVSSGSEKLFS
Site 15S1479GSEKLFSSKSNAQFK
Site 16S1507KLPTDPSSDEPVFHI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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