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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PKD2L2
Full Name:
Polycystic kidney disease 2-like 2 protein
Alias:
Type:
Mass (Da):
73774
Number AA:
624
UniProt ID:
Q9NZM6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
Y
R
K
E
V
E
I
T
T
T
L
Q
E
L
L
Site 2
Y56
M
V
N
P
H
M
Y
Y
L
N
K
V
M
S
S
Site 3
T68
M
S
S
L
F
L
D
T
S
V
P
G
E
E
R
Site 4
S69
S
S
L
F
L
D
T
S
V
P
G
E
E
R
T
Site 5
S80
E
E
R
T
N
F
K
S
I
R
S
I
T
D
F
Site 6
Y100
G
P
L
L
E
G
L
Y
W
D
S
W
Y
N
N
Site 7
Y111
W
Y
N
N
Q
Q
L
Y
N
L
K
N
S
S
R
Site 8
Y120
L
K
N
S
S
R
I
Y
Y
E
N
I
L
L
G
Site 9
Y121
K
N
S
S
R
I
Y
Y
E
N
I
L
L
G
V
Site 10
T140
Q
L
K
V
R
N
N
T
C
K
V
Y
S
S
F
Site 11
Y144
R
N
N
T
C
K
V
Y
S
S
F
Q
S
L
M
Site 12
S145
N
N
T
C
K
V
Y
S
S
F
Q
S
L
M
S
Site 13
S146
N
T
C
K
V
Y
S
S
F
Q
S
L
M
S
E
Site 14
S149
K
V
Y
S
S
F
Q
S
L
M
S
E
C
Y
G
Site 15
S152
S
S
F
Q
S
L
M
S
E
C
Y
G
K
Y
T
Site 16
S160
E
C
Y
G
K
Y
T
S
A
N
E
D
L
S
N
Site 17
S166
T
S
A
N
E
D
L
S
N
F
G
L
Q
I
N
Site 18
S179
I
N
T
E
W
R
Y
S
T
S
N
T
N
S
P
Site 19
T180
N
T
E
W
R
Y
S
T
S
N
T
N
S
P
W
Site 20
T203
R
N
G
G
Y
I
F
T
L
S
K
S
K
S
E
Site 21
S205
G
G
Y
I
F
T
L
S
K
S
K
S
E
T
K
Site 22
S207
Y
I
F
T
L
S
K
S
K
S
E
T
K
N
K
Site 23
S209
F
T
L
S
K
S
K
S
E
T
K
N
K
F
I
Site 24
T211
L
S
K
S
K
S
E
T
K
N
K
F
I
D
L
Site 25
S222
F
I
D
L
R
L
N
S
W
I
T
R
G
T
R
Site 26
Y274
Y
S
V
K
L
L
R
Y
V
S
Y
Y
D
Y
F
Site 27
Y280
R
Y
V
S
Y
Y
D
Y
F
I
A
S
C
E
I
Site 28
Y311
I
K
E
F
K
S
A
Y
F
K
S
I
W
N
W
Site 29
S351
L
L
G
Q
L
L
K
S
T
E
K
Y
S
D
F
Site 30
T352
L
G
Q
L
L
K
S
T
E
K
Y
S
D
F
Y
Site 31
Y355
L
L
K
S
T
E
K
Y
S
D
F
Y
F
L
A
Site 32
S356
L
K
S
T
E
K
Y
S
D
F
Y
F
L
A
C
Site 33
T392
K
F
I
S
F
N
K
T
M
S
Q
L
S
S
T
Site 34
S394
I
S
F
N
K
T
M
S
Q
L
S
S
T
L
S
Site 35
S397
N
K
T
M
S
Q
L
S
S
T
L
S
R
C
V
Site 36
S398
K
T
M
S
Q
L
S
S
T
L
S
R
C
V
K
Site 37
T399
T
M
S
Q
L
S
S
T
L
S
R
C
V
K
D
Site 38
S401
S
Q
L
S
S
T
L
S
R
C
V
K
D
I
V
Site 39
S437
G
S
Q
V
D
D
F
S
T
F
Q
N
S
I
F
Site 40
T438
S
Q
V
D
D
F
S
T
F
Q
N
S
I
F
A
Site 41
Y494
L
A
I
I
N
D
T
Y
S
E
V
K
A
D
Y
Site 42
S495
A
I
I
N
D
T
Y
S
E
V
K
A
D
Y
S
Site 43
Y501
Y
S
E
V
K
A
D
Y
S
I
G
R
R
P
D
Site 44
S502
S
E
V
K
A
D
Y
S
I
G
R
R
P
D
F
Site 45
S518
L
G
K
M
I
K
Q
S
Y
K
N
V
L
E
K
Site 46
Y519
G
K
M
I
K
Q
S
Y
K
N
V
L
E
K
F
Site 47
T539
Q
K
D
E
D
K
K
T
K
G
S
G
D
L
A
Site 48
Y576
K
E
R
L
E
K
K
Y
Y
S
M
E
I
Q
D
Site 49
Y577
E
R
L
E
K
K
Y
Y
S
M
E
I
Q
D
D
Site 50
S578
R
L
E
K
K
Y
Y
S
M
E
I
Q
D
D
Y
Site 51
Y585
S
M
E
I
Q
D
D
Y
Q
P
V
T
Q
E
E
Site 52
T589
Q
D
D
Y
Q
P
V
T
Q
E
E
F
R
E
L
Site 53
Y599
E
F
R
E
L
F
L
Y
A
V
E
L
E
K
E
Site 54
Y609
E
L
E
K
E
L
H
Y
I
N
L
K
L
N
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation